Michael Wakelam - Selected Publications#

March 2019 H-factor = 62, Google Scholar total citations = >13,900

Nguyen, A., Guedan, A., Mousnier, A., Swieboda, D, Zhang, Q., Horkai, D., Le Novere, N., Solari, R. & Wakelam, M.J.O. (2018) Host lipidome analysis during rhinovirus replication in human bronchial epithelial cells identifies potential therapeutic targets. J Lipid Res 59, 1671-1684

Farquhar MJ, Humphreys IS, Rudge SA, Wilson GK, Bhattacharya B, Ciaccia M, Hu K, Zhang Q, Mailly L, Reynolds GM, Aschcroft M, Balfe P, Baumert TF, Roessler S, Wakelam MJ*, & McKeating JA*. (2017) “Autotaxin-lysophosphatidic acid receptor signaling regulates hepatitis C virus regulation” J. Hepatol. 66, 919-929 (12 citations March 2019)

Hahn O, Grönke S, Stubbs TM, Ficz G, Hendrich O, Krueger F, Andrews S, Zhang Q, Wakelam MJ, Beyer A, Reik W & Partridge L. (2017) Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism. Genome Biology 18, 56 (38 citations, March 2019)

Jethwa SA, Leah EJ, Zhang Q, Bright NA, Oxley D, Bootman MD, Rudge SA, Wakelam MJ. (2016) “Exosomes bind autotaxin and act as a physiological delivery mechanism to stimulate LPA receptor signalling in cells.” J Cell Sci. 129, 3948-3957 (11 citations, March 2019)

Peck, B., Schug, Z.T., Zhang, Q., Dankworth, B., Jones, D.T., Smethurst, E., Patel, R., Mason, S., Jiang, M., Saunders, R., Howell, M., Mitter, R., Spencer-Dene, B., Stamp, G., McGarry, L., James, D., Shanks, E., Aboagye, E.O., Critchlow, S.E., Leung, H.Y., Harris, A.L., Wakelam, M.J.O., Gottlieb, E. & Schulze, A. (2016) “Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments” Cancer Metab. 4:6 (48 citations, March 2019)

Cader MZ, Boroviak K, Zhang Q, Assadi G, Kempster SL, Sewell GW, Saveljeva S, Ashcroft JW, Clare S, Mukhopadhyay S, Brown KP, Tschurtschenthaler M, Raine T, Doe B, Chilvers ER, Griffin JL, Kaneider NC, Floto RA, D'Amato M, Bradley A, Wakelam M.J.O, Dougan G, Kaser A. (2016) “C13orf31 (FAMIN) is a central regulator of immunometabolic function.” Nature Immunol. 17:1046-56. (47 citations, March 2019)

Schug, Z.T., Peck, B., Zhang, Q., Jones, D.T., Grosskurth, S., Alam, I.S., Smethurst, E., Mason, S., Blyth, K., McGarry, L., James, D., Shanks, E., Kalna, G., Saunders, B., Jiang, M., Howell, M., Lassailly, F., Thin, M. Z., Spencer-Dene, B., Stamp, G., Tardito, S., Harris, A.L., Aboagye, E.O., Critchlow, S.E., Wakelam, M.J.O.*, Schulze, A*. & Gottlieb, E*. (2015) “Acetyl-coA synthetase 2 promotes acetate utilization and maintains cancer cell growth under nutrient stress.” Cancer Cell 27, 57-71 (254 citations, March 2019)

Bensaad, K., Favaro, E., Lewis, C.A., Peck, B., Lord, S., Collins, J.M., Pinnick, K.E., Wigfield, S., Buffa, F.M., Li, J.-L., Zhang, Q., Wakelam, M.J.O., Karpe, F., Schulze, A. & Harris, A.L. (2014) “Fatty acid uptake and lipid storage induced by HIF-1a contribute to cell growth and survival after hypoxia-regeneration.” Cell Reports 9, 349-365 (131 citations, March 2019)

Liebisch,G., Vizcaíno, J.A., Köfeler, H., Trötzmüller, M., Griffiths, W.J., Schmitz, G., Spener, F., & Wakelam, M.J.O. (2013) „Shorthand notation for lipid structures derived from mass spectrometry.“ J Lipid Res 54, 1523-1530 (282 citations, March 2019)

Lindhurst, M.J., Parker, V.E., Payne, F., Sapp, J.C., Rudge, S.A., Harris, J., Witkowski, A.M., Zhang, Q., Groeneveld, M.P., Scott, C.E., Daly, A., Huson, S.M., Tosi, L.L., Cunningham, M.L., Darling, T.N., Geer, J., Gucev, Z., Sutton, V.R., Tziotzios, C., Dixon, A.K., Helliwell, T., O’Rahilly, S., Savage, D.B., Wakelam, M.J.O., Barroso, I., Biesecker, L.G. & Semple, R.K. (2012) “Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA” Nature Genetics 44, 928-933 (185 citations, March 2019)

(* co-corresponding authors)