Pawel Swietach - Curriculum Vitae#

CURRENT POSITION

• 2020 - present Professor of Physiology, Oxford University
  
• 2016 - present Head of Proton Transport Group, DPAG, Oxford University
  
• 2011 - present Associate Professor in Cardiovascular Physiology, DPAG, Oxford University
  
• 2011 - present Handa Tutorial Fellow and Governing Body member, Corpus Christi College, Oxford

EDUCATION

• 2001 - 2004 Doctorate (DPhil) in Physiology, University of Oxford
  
• 1998 - 2001 Degree (BA) in Physiological Sciences, First Class Honours, Oxford University

POST-DOCTORAL RESEARCH TRAINING

• 2008 - 2016 Royal Society Research Fellow, between DPAG and WIMM; Mentor: Adrian Harris
  
• 2004 - 2008 British Heart Foundation research assistant, DPAG; Director: Richard Vaughan-Jones
  
• 2005, 2007 Visiting scientist, CVRTI, Salt Lake City, USA; Director: Prof Kenneth W Spitzer

SELECTECT RESEARCH GRANTS

• 2022 EVOX therapeutics research grant “Delivering exosomes to the heart” £150,000. 1 year.
  
• 2022 Hemanext Inc research grant “Improving transfusion efficacy with hypoxic storage” £88,000. 2 years
  
• 2022 BLOODMARK ERC Proof-of-Concept grant. EUR150,000. 18 months.
  
• 2021 British Heart Foundation: Project grant: “Curtailing maladaptive cardiac hypertrophy with inhibitors against the surface-expressed NBCn1 (Slc4a7) protein: A novel and accessible anti-hypertrophic target with reduced burden of side-effects”. £274,350. 3 years.
  
• 2020 Propionic Acidemia Foundation: “Epigenetic editing by propionate: Using an inborn error of metabolism to study the cardiac actions of a biologically-active metabolic intermediate”. £50,000
  
• 2018 European Commission: Marie Sklodowska-Curie Initial Training Network: “PHIONIC pH and Ion Transport in Pancreatic Cancer”. £193,964 (PI in Oxford). 4 years
  
• 2017 European Research Council: Consolidator grant: “Surviving metabolism: acid handling and signalling”. ERC-2016-COG-723997. €1,922,575 (as PI). 5 years
  
• 2016 British Heart Foundation: Project grant: “Regulation of nuclear pH in ventricular myocytes and its role in gene expression”. PG/16/66/32288. £226,672 (as PI). 3 years from 2017
  
• 2016 British Heart Foundation:Programme Grant: “H+ ion control and signalling in cardiac hypertrophy and heart failure”. RG07/31534. £1,198,466 (as PI). 5 years
  
• 2015 Children Living with Metabolic Diseases: Project grant: “Mechanisms of aberrant cardiac calcium signalling in response to propionic acidosis”. £16,000 (as PI) 2 years
  
• 2015 EP Abraham Fund: Research grant: “Regulation of cancer cell pH by stromal fibroblasts: studies of novel cancer-stroma interactions”. £30,000 (as PI)
  
• 2013 Qatar National Research Fund: Project grant: “Variation and co-variation in calcium-handling fluxes in the aging cardiac myocyte”. Jointly with Bollensdrorff (Doha) and Niederer (KCL). $897,000 (joint PI)
  
• 2012 British Heart Foundation: Project grant: “Effects of nitric oxide signalling on proton dynamics in the healthy and diseased heart”. PG/12/2/29324. : £188,409 (as PI) 3 years
  
• 2011 Association for International Cancer Research: Project grant: “Regulation of cancer cell pH by stromal fibroblasts: studies of novel cancer-stroma interactions”. #12-0027. £191,403 (as PI) 3 years
  
• 2011 European Commission: Marie Curie Initial Training Network Grant: “IonTrac: Ion transport proteins in control of cancer cell behaviour”. FP7-289648. £193,964 (PI in Oxford) 4 years
  
• 2010 OUP John Fell Fund: Equipment grant: “High resolution, real-time imaging of living cells and tissue: a laboratory start-up”. 092/248. £59,000 (as PI)
  
• 2010 Royal Society Equipment grant: “A high-throughput flow-cytometry system for measuring intracellular pH (pHi) in populations of cells”. £50,000 (as PI)
  
• 2008 Medical Research Council: New Investigator grant: “Mechanisms, consequences and regulation of pH non-uniformity in 3-D tissue structures: implications on cancer therapy”. G0700698. £306,221 (as PI)
  
• 2008 Royal Society: University Research Fellowship “How tissues remove acid: imaging spatial pH regulation in 3-D tumours”. UF120043. £810,998 (as PI) 8 years

RESEARCH FELLOWSHIPS, HONOURS AND AWARDS

• 2018 Inaugural CRUK-U. S. Fulbright Scholar (to Moffitt Cancer Center, USA)
  
• 2018 Elected to Fellowship of the Physiological Society
  
• 2017 - 2022 European Research Council (ERC) Consolidator Grant Awardee
  
• 2008 - 2016 Royal Society University Research Fellow
  
• 2009 - 2012 Medical Research Council New Investigator

SELECTED PUBLICATIONS

ACCEPTED ARTICLES IN PRESS

99 Swietach, Boedtkjer, Pedersen “How protons pave the way to aggressive cancers”, Nature Reviews Cancer

98 Park, Crump, Louwman, Krywawych, Cheong, Vendrell, Gill, Gunadasa-Rohling, Ford, Hauton, Fournier, Pires, Watson, Roseman, Holder, Koschinski, Carnicer, Curtis, Zaccolo, Hulikova, Fischer, Kramer, McCullagh, Trefely, Milne, Swietach “Park, Crump, Louwman, Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation” Nature Cardiovasc Res

PREPRINTS UNDER REVIEW

97 Dumbill, Rabcuka, Knight, Hunter, Fallon, Voyce, Barrett, Ellen, Weissenbacher, Kurniawan, Blonski, Korczyk, Ploeg, Coussios, Friend, Swietach “Diffusion-limited O2 release in human kidneys perfused with stored blood” https://doi.org/10.1101/2023.05.07.23289584

PEER-REVIEWED ARTICLES

96 Michl, Monterisi, White, Blaszczak, Hulikova, Abdullayeva, Bridges, Yin, Bodmer & Swietach. "Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2". Cell Rep (2023)

95 Rabcuka, Blonski, Meli, Sowemimo-Coker, Zaremba, Stephenson, Dzieciatkowska, Nerguizian, Cardigan, Korczyk, Smethurst, D'Alessandro & Swietach. "Metabolic reprogramming under hypoxic storage preserves faster oxygen unloading from stored red blood cells". Blood Adv (2022)

94 Monterisi, Michl, Hulikova, Koth, Bridges, Hill, Abdullayeva, Bodmer, Swietach & Jiang. "Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes". Elife (2022)

93 Riabiz, Chen, Cockayne, Swietach, Niederer, Mackey & Oates. "Optimal thinning of MCMC output". J Roy Stat Soc B (2022)

92 Blaszczak, Williams & Swietach. "Autoregulation of H+/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production". Brit J Cancer (2022)

91 Wilson, Richards, Curtis, Rohling, Monterisi, Loonat, Miller, Ball, Lewis, Tyler, Moshnikova, Andreev, Reshetnyak, Carr & Swietach. "Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH". Cardiovasc Res (2022)

90 Pillai, Mahmud, Mahar, Griffith, Langsen, Nguyen, Wojtkowiak, Swietach, Gatenby, Bui, Merritt, McDonald, Garrett & Gillies. "Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy". Cell Rep (2022)

89 Michl, Wang, Monterisi, Blaszczak, Beveridge, Bridges, Koth, Bodmer & Swietach. "CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH". Cell Rep (2022)

88 Park, Crump, Hulikova, Ford, Louwman, Carnicer, Hauton, Koschinski, Mccullagh, Zaccolo, Krywawych, Milne & Swietach. "Elevated propionate signalling drives Pde9a overexpression and contractile dysfunction through increased histone acetylation and propionylation". Cardiovasc Res (2022)

87 Russell, Xu, Kam, Abrahams, Ordway, Lopez, Bui, Johnson, Epstein, Ruiz, Lloyd, Swietach, Verduzco, Wojtkowiak & Gillies. "Proton export upregulates aerobic glycolysis". Bmc Biol (2022)

86 Donovan, Meli, Cendali, Park, Cardigan, Stanworth, McKechnie, D'Alessandro, Smethurst & Swietach. "Stored blood has compromised oxygen unloading kinetics that can be normalized with rejuvenation and predicted from corpuscular side-scatter". Haematologica (2022)

85 Hulikova, Park, Loonat, Gunadasa-Rohling, Curtis, Chung, Wilson, Carr, Trafford, Fournier, Moshnikova, Andreev, Reshetnyak, Riley, Smart, Milne, Crump & Swietach. "Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart". Basic Res Cardiol (2022)

84 Blaszczak, Tan & Swietach. "Cost-Effective Real-Time Metabolic Profiling of Cancer Cell Lines for Plate-Based Assays". Chemosensors (2021)

83 Kandilci, Richards, Fournier, Simsek, Chung, Lakhal-Littleton & Swietach. "Cardiomyocyte Na+/H+ Exchanger-1 Activity Is Reduced in Hypoxia". Front Cardiovasc Med (2021)

82 Chung, Swietach, Curtis, Ball, Robbins & Lakhal-Littleton. "Iron-Deficiency Anemia Results in Transcriptional and Metabolic Remodeling in the Heart Toward a Glycolytic Phenotype". Front Cardiovasc Med (2021)

81 Ordway, Tomaszewski, Byrne, Abrahams, Swietach, Gillies & Damaghi. "Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities". Cancers (2021)

80 Simon, Vrellaku, Monterisi, Chu, Rawlings, Lomas, Marchal, Waithe, Syeda, Gajendragadkar, Jayaram, Sayeed, Channon, Fabritz, Swietach, Zaccolo, Eaton & Casadei. "Oxidation of Protein Kinase A Regulatory Subunit PKARI alpha Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release". Circulation (2021)

79 Chung, Park, Tokar, Eykyn, Fuller, Pavlovic, Swietach & Shattock. "SGLT2 inhibitors and the cardiac Na+/H+ exchanger-1: the plot thickens". Cardiovasc Res (2021)

78 Chung, Park, Tokar, Eykyn, Fuller, Pavlovic, Swietach & Shattock. "Off-target effects of sodium-glucose co-transporter 2 blockers: empagliflozin does not inhibit Na+/H+ exchanger-1 or lower [Na+]](i) in the heart". Cardiovasc Res (2021)

77 Hulikova, Kramer, Khan & Swietach. "Detection of Intravascular Hemolysis in Newborn Infants Using Urinary Carbonic Anhydrase I Immunoreactivity". J Appl Lab Med (2020)

76 Richards, Simon, Ma, Loonat, Crabtree, Paterson, Fahlman, Casadei, Fliegel & Swietach. "Nitric oxide modulates cardiomyocyte pH control through a biphasic effect on sodium/hydrogen exchanger-1". Cardiovasc Res (2020)

75 Richardson, Hulikova, Proven, Hipkiss, Akanni, Roy & Swietach. "Single-cell O-2 exchange imaging shows that cytoplasmic diffusion is a dominant barrier to efficient gas transport in red blood cells". P Natl Acad Sci USA (2020)

74 Park, Krywawych, Richard, Desviat & Swietach. "Cardiac Complications of Propionic and Other Inherited Organic Acidemias". Front Cardiovasc Med (2020)

73 Wu, Estrella, Beatty, Abrahams, El-Kenawi, Russell, Ibrahim-Hashim, Longo, Reshetnyak, Moshnikova, Andreev, Luddy, Damaghi, Kodumudi, Pillai, Enriquez-Navas, Pilon-Thomas, Swietach & Gillies. "T-cells produce acidic niches in lymph nodes to suppress their own effector functions". Nat Commun (2020)

72 Park, Donovan, McKechnie, Ramamurthy, Klenerman & Swietach. "Single-cell oxygen saturation imaging shows that gas exchange by red blood cells is not impaired in COVID-19 patients". Brit J Haematol (2020)

71 Loonat, Curtis, Richards, Nunez-Alonso, Michl & Swietach. "A high-throughput ratiometric method for imaging hypertrophic growth in cultured primary cardiac myocytes". J Mol Cell Cardiol (2019)

70 Michl, Park & Swietach. "Evidence-based guidelines for controlling pH in mammalian live-cell culture systems". Commun Biol (2019)

69 Chung, Luo, Park, Loonat, Lakhal-Littleton, Robbins & Swietach. "Iron-deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity". Jci Insight (2019)

68 Simsek, Vaughan-Jones, Swietach & Kandilci. "Recovery from hypoxia-induced internalization of cardiac Na+/H (+) exchanger 1 requires an adequate intracellular store of antioxidants". J Cell Physiol (2019)

67 Rorsman, Ta, Garnett, Swietach & Tammaro. "Defining the ionic mechanisms of optogenetic control of vascular tone by channelrhodopsin-2". Brit J Pharmacol (2018)

66 Burdyga, Surdo, Monterisi, Di Benedetto, Grisan, Penna, Pellegrini, Bortolozzi, Swietach, Pozzan & Lefkimmiatis. "Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane". P Natl Acad Sci USA (2018)

65 Dovmark, Hulikova, Niederer, Vaughan-Jones & Swietach. "Normoxic cells remotely regulate the acid-base balance of cells at the hypoxic core of connexin-coupled tumor growths". Faseb J (2018)

64 Lee, Mcintyre, Honess, Hulikova, Pacheco-Torres, Cerdan, Swietach, Harris & Griffiths. "Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo". Brit J Cancer (2018)

63 Garciarena, Malik, Swietach, Moreno & Vaughan-Jones. "Distinct moieties underlie biphasic H+ gating of connexin43 channels, producing a pH optimum for intercellular communication". Faseb J (2018)

62 Ford, Moorhouse, Bortolozzi, Richards, Swietach & Vaughan-Jones. "Regional acidosis locally inhibits but remotely stimulates Ca2+ waves in ventricular myocytes". Cardiovasc Res (2017)

61 Dovmark, Saccomano, Hulikova, Alves & Swietach. "Connexin-43 channels are a pathway for discharging lactate from glycolytic pancreatic ductal adenocarcinoma cells". Oncogene (2017)

60 Hulikova, Black, Hsia, Wilding, Bodmer & Swietach. "Stromal uptake and transmission of acid is a pathway for venting cancer cell-generated acid". P Natl Acad Sci USA (2016)

59 Richardson & Swietach. "Red blood cell thickness is evolutionarily constrained by slow, hemoglobin-restricted diffusion in cytoplasm". Sci Rep (2016)

58 Richards, Lomas, Jalink, Ford, Vaughan-Jones, Lefkimmiatis & Swietach. "Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes". Cardiovasc Res (2016)

57 McIntyre, Hulikova, Ledaki, Snell, Singleton, Steers, Seden, Jones, Bridges, Wigfield, Li, Russell, Swietach & Harris. "Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth". Cancer Res (2016)

56 Hulikova & Swietach. "Nuclear proton dynamics and interactions with calcium signaling". J Mol Cell Cardiol (2016)

55 Swietach, Spitzer & Vaughan-Jones. "Na+ ions as spatial intracellular messengers for co-ordinating Ca2+ signals during pH heterogeneity in cardiomyocytes". Cardiovasc Res (2015)

54 Hulikova, Aveyard, Harris, Vaughan-Jones & Swietach. "Intracellular Carbonic Anhydrase Activity Sensitizes Cancer Cell pH Signaling to Dynamic Changes in CO2 Partial Pressure". J Biol Chem (2014)

53 Villafuerte, Swietach, Youm, Ford, Cardenas, Supuran, Cobden, Rohling & Vaughan-Jones. "Facilitation by intracellular carbonic anhydrase of Na+-HCO3- co-transport but not Na+/H+ exchange activity in the mammalian ventricular myocyte". J Physiol-London (2014)

52 Hulikova & Swietach. "Rapid CO2 permeation across biological membranes: implications for CO2 venting from tissue". Faseb J (2014)

51 Gondi, Mysliwietz, Hulikova, Jen, Swietach, Kremmer & Zeidler. "Antitumor Efficacy of a Monoclonal Antibody That Inhibits the Activity of Cancer-Associated Carbonic Anhydrase XII". Cancer Res (2013)

50 Swietach, Youm, Saegusa, Leem, Spitzer & Vaughan-Jones. "Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling". P Natl Acad Sci USA (2013)

49 Garciarena, Ma, Swietach, Huc & Vaughan-Jones. "Sarcolemmal localisation of Na+/H+ exchange and Na+HCO3- co-transport influences the spatial regulation of intracellular pH in rat ventricular myocytes". J Physiol-London (2013)

48 Schroeder, Ali, Hulikova, Supuran, Clarke, Vaughan-Jones, Tyler & Swietach. "Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics". P Natl Acad Sci USA (2013)

47 McIntyre, Hulikova, Ledaki, Seden, Turley, Jones, Russell, Swietach & Harris. "Hypoxic trans-activation of sodium dependent bicarbonate co-transporters regulates pH in 3D spheroids and promotes growth". Cancer Res (2013)

46 Hulikova, Harris, Vaughan-Jones & Swietach. "Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia". J Cell Physiol (2013)

45 McIntyre, Patiar, Wigfield, Li, Ledaki, Turley, Leek, Snell, Gatter, Sly, Vaughan-Jones, Swietach & Harris. "Carbonic Anhydrase IX Promotes Tumor Growth and Necrosis In Vivo and Inhibition Enhances Anti-VEGF Therapy". Clin Cancer Res (2012)

44 Swietach, Hulikova, Patiar, Vaughan-Jones & Harris. "Importance of Intracellular pH in Determining the Uptake and Efficacy of the Weakly Basic Chemotherapeutic Drug, Doxorubicin". Plos One (2012)

43 Murri-Plesko, Hulikova, Oosterwijk, Scott, Zortea, Harris, Ritter, Old, Bauer, Swietach & Renner. "Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX". Eur J Pharmacol (2011)

42 Hulikova, Vaughan-Jones & Swietach. "Dual Role of CO2/HCO3- Buffer in the Regulation of Intracellular pH of Three-dimensional Tumor Growths". J Biol Chem (2011)

41 Li, Niederer, Idigo, Zhang, Swietach, Casadei & Smith. "A mathematical model of the murine ventricular myocyte: a data-driven biophysically based approach applied to mice overexpressing the canine NCX isoform". Am J Physiol-Heart C (2010)

40 Swietach, Camelliti, Hulikova, Kohl & Vaughan-Jones. "Spatial regulation of intracellular pH in multicellular strands of neonatal rat cardiomyocytes". Cardiovasc Res (2010)

39 Everaert, Willemsen, Hulikova, Brown, Decuypere, Swietach & Bruggeman. "The importance of carbonic anhydrase II in red blood cells during exposure of chicken embryos to CO2". Resp Physiol Neurobi (2010)

38 Swietach, Spitzer & Vaughan-Jones. "Modeling calcium waves in cardiac myocytes: importance of calcium diffusion". Front Biosci-Landmrk (2010)

37 Swietach, Tiffert, Mauritz, Seear, Esposito, Kaminski, Lew & Vaughan-Jones. "Hydrogen ion dynamics in human red blood cells". J Physiol-London (2010)

36 Schroeder, Swietach, Atherton, Gallagher, Lee, Radda, Clarke & Tyler. "Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a C-13 and P-31 magnetic resonance spectroscopy study". Cardiovasc Res (2010)

35 Swietach, Patiar, Supuran, Harris & Vaughan-Jones. "The Role of Carbonic Anhydrase 9 in Regulating Extracellular and Intracellular pH in Three-dimensional Tumor Cell Growths". J Biol Chem (2009)

34 Huang, Swietach, Vaughan-Jones & Glitsch. "Differentiation impairs low pH-induced Ca2+ signaling and ERK phosphorylation in granule precursor tumour cells". Cell Calcium (2009)

33 Huang, Swietach, Vaughan-Jones, Ansorge & Glitsch. "Extracellular acidification elicits spatially and temporally distinct Ca2+ signals". Curr Biol (2008)

32 Ch'en, Villafuerte, Swietach, Cobden & Vaughan-Jones. "S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart". Brit J Pharmacol (2008)

31 Swietach, Wigfield, Supuran, Harris & Vaughan-Jones. "Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion". Bju Int (2008)

30 Swietach, Wigfield, Cobden, Supuran, Harris & Vaughan-Jones. "Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths". J Biol Chem (2008)

29 Swietach, Spitzer & Vaughan-Jones. "Ca2+-Mobility in the sarcoplasmic reticulum of ventricular myocytes is low". Biophys J (2008)

28 Swietach, Spitzer & Vaughan-Jones. "pH-dependence of extrinsic and intrinsic H+-ion mobility in the rat ventricular myocyte, investigated using flash photolysis of a caged-H+ compound". Biophys J (2007)

27 Swietach, Rossini, Spitzer & Vaughan-Jones. "H+ ion activation and inactivation of the ventricular gap junction - A basis for spatial regulation of intracellular pH". Circ Res (2007)

26 Yamamoto, Swietach, Rossini, Loh, Vaughan-Jones & Spitzer. "Functional diversity of electrogenic Na+-HCO3- cotransport in ventricular myocytes from rat, rabbit and guinea pig". J Physiol-London (2005)

25 Swietach & Vaughan-Jones. "Relationship between intracellular pH and proton mobility in rat and guinea-pig ventricular myocytes". J Physiol-London (2005)

24 Swietach, Leem, Spitzer & Vaughan-Jones. "Experimental generation and computational modeling of intracellular pH gradients in cardiac myocytes". Biophys J (2005)

23 Swietach & Vaughan-Jones. "Novel method for measuring junctional proton permeation in isolated ventricular myocyte cell pairs". Am J Physiol-Heart C (2004)

22 Zaniboni, Swietach, Rossini, Yamamoto, Spitzer & Vaughan-Jones. "Intracellular proton mobility and buffering power in cardiac ventricular myocytes from rat, rabbit, and guinea pig". Am J Physiol-Heart C (2003)

21 Zaniboni, Rossini, Swietach, Banger, Spitzer & Vaughan-Jones. "Proton permeation through the myocardial gap junction". Circ Res (2003)

20 Ch'en, Dilworth, Swietach, Goddard & Vaughan-Jones. "Temperature dependence of Na+-H+ exchange, Na+-HCO3- co-transport, intracellular buffering and intracellular pH in guinea-pig ventricular myocytes". J Physiol-London (2003)

19 Swietach, Browning & Wilkins. "Functional and molecular determination of carbonic anhydrase levels in bovine and cultured human chondrocytes". Comp Biochem Phys B (2002)

EDITORIALS AND INVITED REVIEWS

18 Swietach & Despa. "Channelling protons out of the heart". J Physiol-London (2022)

17 Blaszczak & Swietach. "What do cellular responses to acidity tell us about cancer?". Cancer Metast Rev (2021)

16 Ordway, Swietach, Gillies & Damaghi. "Causes and Consequences of Variable Tumor Cell Metabolism on Heritable Modifications and Tumor Evolution". Front Oncol (2020)

15 Swietach. "What is pH regulation, and why do cancer cells need it?". Cancer Metast Rev (2019)

14 Swietach & Monterisi. "A Barter Economy in Tumors: Exchanging Metabolites through Gap Junctions". Cancers (2019)

13 Hulikova, Vaughan-Jones, Niederer & Swietach. "CrossTalk opposing view: Physiological CO2 exchange does not normally depend on membrane channels". J Physiol-London (2015)

12 Swietach, Vaughan-Jones, Harris & Hulikova. "The chemistry, physiology and pathology of pH in cancer". Philos T R Soc B (2014)

11 Swietach, Leem, Spitzer & Vaughan-Jones. "Pumping Ca2+ up H+ gradients: a Ca2+-H+ exchanger without a membrane". J Physiol-London (2014)

10 Garciarena, Youm, Swietach & Vaughan-Jones. "H+-activated Na+ influx in the ventricular myocyte couples Ca2+-signalling to intracellular pH". J Mol Cell Cardiol (2013)

9 Hulikova, Harris, Vaughan-Jones & Swietach. "Acid-extrusion from Tissue: The Interplay Between Membrane Transporters and pH Buffers". Curr Pharm Design (2012)

8 Swietach, Hulikova, Vaughan-Jones & Harris. "New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation". Oncogene (2010)

7 Swietach, Harris & Vaughan-Jones. "The Tumor Microenvironment: New Insights into Regulation of Tumor pH by Carbonic Anhydrases". Cancer Drug Discov D (2010)

6 Vaughan-Jones, Spitzer & Swietach. "Intracellular pH regulation in heart". J Mol Cell Cardiol (2009)

5 Vaughan-Jones & Swietach. "Pushing and pulling the cardiac sodium/hydrogen exchanger". Circ Res (2008)

4 Swietach, Vaughan-Jones & Harris. "Regulation of tumor pH and the role of carbonic anhydrase 9". Cancer Metast Rev (2007)

3 Vaughan-Jones, Spitzer & Swietach. "Spatial aspects of intracellular pH regulation in heart muscle". Prog Biophys Mol Bio (2006)

2 Swietach & Vaughan-Jones. "Spatial regulation of intracellular pH in the ventricular myocyte". Ann Ny Acad Sci (2005)

1 Swietach, Zaniboni, Stewart, Rossini, Spitzer & Vaughan-Jones. "Modelling intracellular H+ ion diffusion". Prog Biophys Mol Bio (2003)