Andreas Radbruch - Selected Publications#

Radbruch A, Chang HD. A long-term perspective on immunity to COVID. Nature. 2021 Jul;595(7867):359-360. doi: 10.1038/d41586-021-01557-z. PMID: 34127832.

Ferreira-Gomes M, Kruglov A, Durek P, Heinrich F, Tizian C, Heinz GA, Pascual-Reguant A, Du W, Mothes R, Fan C, Frischbutter S, Habenicht K, Budzinski L, Ninnemann J, Jani PK, Guerra GM, Lehmann K, Matz M, Ostendorf L, Heiberger L, Chang HD, Bauherr S, Maurer M, Schönrich G, Raftery M, Kallinich T, Mall MA, Angermair S, Treskatsch S, Dörner T, Corman VM, Diefenbach A, Volk HD, Elezkurtaj S, Winkler TH, Dong J, Hauser AE, Radbruch H, Witkowski M, Melchers F, Radbruch A, Mashreghi MF. SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself. Nat Commun. 2021 Mar 30;12(1):1961. doi: 10.1038/s41467-021-22210-3. PMID: 33785765; PMCID:PMC8010106.

Maschmeyer P, Heinz GA, Skopnik CM, Lutter L, Mazzoni A, Heinrich F, von Stuckrad SL, Wirth LE, Tran CL, Riedel R, Lehmann K, Sakwa I, Cimaz R, Giudici F, Mall MA, Enghard P, Vastert B, Chang HD, Durek P, Annunziato F, van Wijk F, Radbruch A, Kallinich T, Mashreghi MF. Antigen-driven PD-1+ TOX+ BHLHE40+ and PD-1+ TOX+EOMES+ T lymphocytes regulate juvenile idiopathic arthritis in situ. Eur J Immunol. 2021 Apr;51(4):915-929. doi: 10.1002/eji.202048797. Epub 2021 Feb 2. PMID: 33296081.

Maschmeyer P, Chang HD, Cheng Q, Mashreghi MF, Hiepe F, Alexander T, Radbruch A. Immunological memory in rheumatic inflammation - a roadblock to tolerance induction. Nat Rev Rheumatol. 2021 May;17(5):291-305. doi: 10.1038/s41584-021-00601-6. Epub 2021 Apr 6. PMID: 33824526.

Cornelis R, Hahne S, Taddeo A, Petkau G, Malko D, Durek P, Thiem M, Heiberger L, Peter L, Mohr E, Klaeden C, Tokoyoda K, Siracusa F, Hoyer BF, Hiepe F, Mashreghi MF, Melchers F, Chang HD, Radbruch A. Stromal Cell-Contact Dependent PI3K and APRIL Induced NF-κB Signaling Prevent Mitochondrial- and ER Stress Induced Death of Memory Plasma Cells. Cell Rep. 2020 Aug 4;32(5):107982. doi: 10.1016/j.celrep.2020.107982. PMID: 32755576; PMCID: PMC7408492.

Riedel R, Addo R, Ferreira-Gomes M, Heinz GA, Heinrich F, Kummer J, Greiff V, D, Klaeden C, Cornelis R, Menzel U, Kröger S, Stervbo U, Köhler R, Haftmann C, Kühnel S, Lehmann K, Maschmeyer P, McGrath M, Naundorf S, Hahne S, Sercan-Alp Ö, Siracusa F, Stefanowski J, Weber M, Westendorf K, Zimmermann J, Hauser AE, Reddy ST, Durek P, Chang HD, Mashreghi MF, Radbruch A. Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow. Nat Commun. 2020 May 22;11(1):2570. doi: 10.1038/s41467-020-16464-6. PMID: 32444631; PMCID: PMC7244721.

Molecular Biology of B cells (Monograph) Elsevier 2nd Edition 2014 ISBN: 9780123979339
Editors: Tasuku Honjo, Michael Reth, Andreas Radbruch, Frederick Alt

Alexander T, Thiel A, Rosen O, Massenkeil G, Sattler A, Kohler S, Mei H, Radtke H, Gromnica-Ihle E, Burmester GR, Arnold R, Radbruch A, Hiepe F. Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system. Blood. 2009 Jan 1;113(1):214-23. doi: 10.1182/blood-2008-07-168286. Epub 2008 Sep 29. PMID: 18824594.

Manz RA, Thiel A, Radbruch A. Lifetime of plasma cells in the bone marrow. Nature. 1997 Jul 10;388(6638):133-4. doi: 10.1038/40540. PMID: 9217150.

Miltenyi S, Müller W, Weichel W, Radbruch A. High gradient magnetic cell separation with MACS. Cytometry. 1990;11(2):231-8. doi: 10.1002/cyto.990110203. PMID: 1690625.