Seamus Martin - Selected Publications#

H-index: 90 (ISI/Clarivate)
Citations (ISI/Clarivate): 40,500
Citations (Google Scholar): 66,116
H-index: 99

Sullivan GP, Davidovich P, Muñoz-Wolf N, Ward RW, Hernandez Santana YE, Clancy DM, Gorman A, Najda Z, Turk B, Walsh PT, Lavelle EC, and Martin SJ. (2022) Myeloid cell-derived proteases produce a pro-inflammatory form of IL-37 that signals via IL-36 receptor engagement. Science Immunology 7, eade5728 1-15.

Sullivan GP, O'Connor H, Henry CM, Davidovich P, Clancy DM, Albert ML, Cullen SP, Martin SJ. (2020) TRAIL Receptors Serve as Stress-Associated Molecular Patterns to Promote ER-Stress-Induced Inflammation. Developmental Cell 52, 714-730.

Clancy DM, Sullivan GP, Moran HBT, Henry CM, Reeves EP, McElvaney NG, Lavelle EC, Martin SJ. (2018). Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing. Cell Reports 22, 2937-2950.

Henry CM and Martin SJ. (2017). Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory "FADDosome" Complex upon TRAIL Stimulation. Molecular Cell 65, 715-729.

Henry CM, Sullivan GP, Clancy DM, Afonina IS, Kulms D, & SJ Martin (2016) Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines. Cell Reports 14: 708-22.

Afonina IS, Müller C, Martin SJ, Beyaert R. (2015) Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme. Immunity 42:991-1004.

Hollville, E., Carroll, R. and S.J. Martin (2014) Bcl-2 Family Proteins Participate in Mitochondrial Quality Control by Regulating Parkin/PINK1-Dependent Mitophagy. Molecular Cell 55, 451-466

Cullen, S.P., Henry, C.M., Kearney, C.J., Logue, S.E., Feoktistova, M., Tynan, G.A., Lavelle, E.C., Leverkus, M. and S. J. Martin (2013) Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells. Molecular Cell 49, 1034-48.

Martin, S.J., Henry, C.M., and Cullen, S.P. (2012) A Perspective on Mammalian Caspases as Positive and Negative Regulators of Inflammation. Molecular Cell 46, 387-397.

Afonina, I.A., Tynan, G.A., Logue, S.E., Cullen, S.P., Bots, M., Lüthi, A.U., Reeves, E.P., McElvaney, N.G., Medema, J.P., Lavelle, E.C. & S.J. Martin (2011) Granzyme B-dependent proteolysis acts as a switch to enhance the pro-inflammatory activity of IL-1alpha. Molecular Cell 44, 265-278.

Elgendy, M., Sheridan, C., Brumatti, G. & S.J. Martin (2011) Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival. Molecular Cell 42:23-35.

Martin, S.J. (2010) Opening the cellular poison cabinet. Science 330, 1330-1331.

Lüthi, A.U., Cullen, S.P., McNeela, E.A., Duriez, P.J., Afonina, I.S., Sheridan, C., Brumatti, G., Taylor, R.C., Kersse, K., Vandenabeele, P., Lavelle, E.C. & S.J. Martin (2009) Suppression of IL-33 Bioactivity through Proteolysis by Apoptotic Caspases. Immunity 31, 84-98.

Autret, A. and S. J. Martin. (2009) Emerging role for members of the Bcl-2 family in mitochondrial morphogenesis. Molecular Cell, 36, 355-363