Terho Lehtimäki - Selected Publications#


Over 1200 peer reviewed publications as well as invited reviews, chapters in books. Over 120.000 citations Google Scholar H-index 147 (2022); Google Scholar i10-index is 891 (=number of publications with at least 10 citations). Ten (10) most citated articles have all over 2000 citations. Name mentioned in two worldwide lists (http://www.webometrics.info/en/hlargerthan100) among the most highly citated investigators with Hirch Index (HI) over 100 and Clarivate Analytics: Highly Cited Researchers 2018 list.

Author in over 330 articles published in world top ranked and most influential journals (IF≈ 79 to ≈8) for example (number of articles/IF), i.e., New England Journal of Medicine (2/IF 91.245) Lancet (7/IF 79.321), JAMA (2/ IF 47.661), Nature (20/IF 42.778), Nature Genetics (57/IF 38.330), Cell (3/38.637), Nature Medicine (1/53.440), Science (3/IF 34.661), Lancet Diabetes Endocrinol. (2/IF 32.069), BMJ (4/IF 30.223), Lancet Respir Med. (1/IF 30.7), Eur Heart J (10/ 22.673), J Am Coll Cardiol. (12/IF 20.589), Circulation (15/ IF 23.603), Nature Neurosci (1/IF 20.071), Selected publications:

Salonen JT, Malin R, Tuomainen T-P, Nyyssönen K, Lakka TA, Lehtimäki T. Polymorphism in high density lipoprotein paraoxonase gene and the risk of acute myocardial infarction in men: prospective nested case-control study. BMJ 1999;319:487–489. IF 30.223. Citations > 90

Valkonen V-P, Päivä H, Salonen JT, Lakka TA, Lehtimäki T, Laakso J, Laaksonen R. Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine. Lancet 2001;358:2127–2128. IF 79.321. Citations > 766.

Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, Yamrom B, Yoon S, Krasnitz A, Kendall J, Leotta A, Pai D, Zhang R, Lee YH, Hicks J, Spence SJ, Lee AT, Puura K, Lehtimäki T, Ledbetter D, Gregersen PK, Bregman J, Sut-Cliffe JS, Jobanputra V, Chung W, Warburton D, King MC, Skuse D, Geschwind DH, Gilliam TC, Ye K, Wigler M. Strong as-association of de novo copy number mutations with autism. Science 2007;316:445-449. IF 34.661. Citations > 3184.

Hernesniemi JA, Karhunen PJ, Oksala N, Kähönen M, Levula M, Rontu R, Ilveskoski E, Kajander O, Goebeler S, Viiri LE, Hurme M, Lehtimäki T. Interleukin 18 gene promoter polymorphism: a link between hypertension and pre-hospital sudden cardiac death: the Helsinki Sudden Death Study. Eur Heart J. 2009;30:2939-46. IF 22.673. Citations > 48

Jacobs D, Woo JG, Sinaiko AR, Daniels SR, Ikonen J, Juonala M, Kartiosuo N, Lehtimäki T, Magnussen CG, Viikari JSA, Zhang N, Bazzanno LA, Burns TL, Prineas RJ, Steinberger J, Urbina EM, Venn AJ, Raitakari OT, Dwyer T. Engl Med 2022; 386:1877-1888. IF 91.245

Seppälä I, Kleber ME, Lyytikäinen LP, Hernesniemi JA, Mäkelä KM, Oksala N, Laaksonen R, Pilz S, Tomaschitz A, Silbernagel G, Boehm BO, Grammer TB, Koskinen T, Juonala M, Hutri-Kähönen N, Alfthan G, Viikari JS, Kähonen M, Raitakari OT, März W, Meinitzer A, Lehtimäki T. Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality. Eur Heart J. 2013;35:524-31. IF 22.673. Citations > 42

Laaksonen J, Seppälä I, Raitoharju E, Mononen N, Lyytikäinen LP, Waldenberger M, Illig T, Lepistö M, Almusa H, Ellonen P, Hutri-Kähönen N, Juonala M, Kähönen M, Raitakari O, Salonen JT, Lehtimäki T. Discovery of mitochondrial DNA variants associated with genome-wide blood cell gene expression: a population-based mtDNA sequencing study. Hum Mol Genet. 2019 Apr 15;28(8):1381-1391. IF 6.150

Hernesniemi JA, Lyytikäinen LP, Oksala N, Seppälä I, Kleber ME, Mononen N, März W, Mikkelsson J, Pessi T, Louhelainen AM, Martiskainen M, Nikus K, Klopp N, Waldenberger M, Illig T, Kähönen M, Laaksonen R, Karhunen PJ, Lehtimäki T. Predicting sudden cardiac death using common genetic risk variants for coronary artery disease. Eur Heart J. 2015;36:1669-75. IF 22.673. Citations > 38

Raitoharju E, Oksala N, Lehtimäki T. MicroRNAs in the atheroclerotic plaque (Review). Clin Chem. 2013;59:1708-21. IF 8.0. Citations > 92

Gusev A, Ko A, Shi H, Bhatia G, Chung W, Penninx BW, Jansen R, DE Geus EJ, Boomsma DI, Wright FA, Sullivan PF, Nikkola E, Alvarez M, Civelek M, Lusis AJ, Lehtimäki T, Raitoharju E, Kähönen M, Seppälä I, Raitakari OT, Kuusisto J, Laakso M, Price Al, Pajukanta P, Pasaniuc B. Integrative approaches for large-scale transcriptome-wide association studies. Nat Genet. 2016;48(3):245-52. IF 36.377. Citations > 1179.

Park I, Goddard ME, Cole JE, Zanin N, Lyytikäinen LP, Lehtimäki T, Andreakos E, Feldmann M, Udalova I, Drozdov I, Monaco C. C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis. Nat Commun. 2022 Jan 11;13(1):215. doi: 10.1038/s41467-021-27862-9. IF 14.919

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