Marc Lecuit - Publications#

H index: 87 ISI Web of science (all databases); 100 Google scholar
333 publications listed in PubMed

Selected list of publications

Charlier C, Barrault Z, Rousseau J, Kermorvant-DucheminE, Meyzer C, Semeraro M, Fall M, Coulpier G, Leclercq A, Charles MA, Ancel PY, Lecuit M
Long-term neurological and neurodevelopmental outcome of neonatal listeriosis in France: a prospective, matched, observational cohort study
Lancet Child Adolesc Health 2023 Oct 20:S2352-4642(23)00195-5

Pommier JD, Gorman C, Crabol Y, Bleakley K, Sothy H, Santy K, Tran HTT, Nguyen LV, Bunnakea E, Hlaing CS, Aye AMM, Cappelle J, Herrant M, Piola P, Rosset B, Chevalier V, Tarantola A, Channa M, Honnorat J, Pinto AL, Rattanavong S, Vongsouvath M, Mayxay M, Phangmanixay S, Phongsavath K, Tin OS, Kyaw LL, Tin HH, Linn K, Tran TMH, Pérot P, Thuy NTT, Hien N, Phan PH, Buchy P, Dussart P, Laurent D, Eloit M, Dubot-Pérès A, Lortholary O, de Lamballerie X, Newton PN, Lecuit M; SEAe Consortium
Childhood encephalitis in the Greater Mekong region (the SouthEast Asia Encephalitis Project): a multicentre prospective study
Lancet Glob Health 2022 Jul;10(7):e989-e1002

Maudet C, Kheloufi M, Levallois S, Gaillard J, Huang L, Gaultier C, Tsai YH, Disson O, Lecuit M
Bacterial inhibition of Fas-mediated killing promotes neuroinvasion and persistence
Nature 2022, 603 (7903), 900-906

Moura A, Lefrancq N, Leclercq A, Wirth T, Borges V, Gilpin B, Dallman TJ, Frey J, Franz E, Nielsen EM, Thomas J, Pightling A, Howden BP, Tarr CL, Gerner-Smidt P, Cauchemez S, Salje H, Brisse S, Lecuit M
Emergence and global spread of Listeria monocytogenes main clinical clonal complex
Sci Adv 2021 Dec 3;7(49):eabj9805

Hafner L, Pichon M, Burucoa C, Moura A, Garcia-Garcera M, Lecuit M
Listeria monocytogenes faecal carriage is common and depends on the gut microbiota
Nat Commun 2021 Nov 24;12(1):6826

Dias De Melo, G, Lazarini F, Levallois S, Hautefort C, Michel V, Larrous F, Verillaud B, Aparicio C, Wagner S, Gheusi G, Kergoat L, Kornobis E, Cokelaer T, Hervochon R, Madec Y, Roze E, Salmon D, Bourhy H, Lecuit M, Lledo PM
COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters
Sci Transl Med 2021 Jun 2;13(596):eabf8396

Kim M, Fevre C, Lavina M, Disson O, Lecuit M.
Live Imaging Reveals Listeria Hijacking of E-Cadherin Recycling as It Crosses the Intestinal Barrier.
Curr Biol 2021 Mar 8;31(5):1037-1047.e4

Travier L, Alonso M, Andronico A, Hafner L, Disson O, Lledo PM, Cauchemez S, Lecuit M.
Neonatal susceptibility to meningitis results from the immaturity of epithelial barriers and gut microbiota.
Cell Rep 2021 Jun 29;35(13):109319

Thomas J, Govender N, McCarthy KM, Erasmus LK, Doyle TJ, Allam M, Ismail A, Ramalwa N, Sekwadi P, Ntshoe G, Shonhiwa A, Essel V, Tau N, Smouse S, Ngomane HM, Disenyeng B, Page NA, Govender NP, Duse AG, Stewart R, Thomas T, Mahoney D, Tourdjman M, Disson O, Thouvenot P, Maury MM, Leclercq A, Lecuit M, Smith AM, Blumberg LH
Outbreak of Listeriosis in South Africa Associated with Processed Meat
N Engl J Med 2020, 382:632–643

Meertens L, Lamine Hafirassou M, Couderc T, Bonnet-Madin L, Kril V, Brugier A, Simon-Loriere E, Burlaud Gaillard J, Doyen C, Pezzi L, Labeau A, Kümmerer B, Vidalain PO, Bertrand Legout A, Gueneau L, Juntas-Morales R, Ben Yao R, Bonne G, de Lamballerie X, Benkirane M, Roingeard P, Delaugerre C, Lecuit M, Amara A
HL1A is a major host factor for chikungunya virus infection
Nature 2019, 574:259–263

Buchrieser J, Degrelle SA, Couderc T, Nevers Q, Disson O, Manet C, Donahue DA, Porrot F, Hillion KH, Perthame E, Arroyo MV, Souquere S, Ruigrok K, Dupressoir A, Heidmann T, Montagutelli X, Fournier T*, Lecuit M*, Schwartz O*
IFITM proteins inhibit placental syncytiotrophoblast formation and promote fetal demise
Science 2019 Jul;365 (6449), 176-180

Maury, MM, Bracq-Dieye H, Huang L, Vales G, Lavina M, Thouvenot P, Disson O, Leclercq A, Brisse S, Lecuit M
Hypervirulent Listeria monocytogenes clones’ adaptation to mammalian gut accounts for their association with dairy products
Nat Commun 2019 Jun 6;10(1):2488

Disson O, Blériot C, Jacob JM, Serafini N, Dulauroy S, Jouvion G, Fèvre C, Gessain G, Thouvenot P, Eberl G, Di Santo J, Lecuit M
Peyer’s patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion
J Exp Med 2018 Nov 5;215(11):2936-2954

Gladwyn-Ng I, Cordon Barris L, Alfano C, Creppe C, Couderc T, Morelli G, Thelen N, America M, Bessières B, Encha-Razavi F, Bonnière M, Suzuki IK, Flamand M, Vanderhaeghen P, Thiry M, Lecuit M*, Nguyen L*
Stress-induced unfolded protein response contributes to Zika virus-associated microcephaly
Nat Neurosci 2018 Jan;21(1):63-71

Charlier C, Perrodeau E, Leclercq A, Cazenave B, Pilmis B, Henry B, Lopes A, Maury M, Moura A, Goffinet F, Bracq Dieye H, Thouvenot P, Ungeheuer MN, Tourdjman M, Goulet V, de Valk H, Lortholary O, Ravaud P, Lecuit M
Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study
Lancet Infect Dis 2017 Jan 28. pii: S1473-3099(16)30521-7

Moura A, Criscuolo A, Pouseele H, Maury MM, Leclercq A, Tarr C, Björkman JT, Dallman T, Reimer A, Enouf V, Larsonneur E, Carleton H, Bracq-Dieye H, Katz LS, Jones L, Touchon M, Tourdjman M, Walker M, Stroika S, Cantinelli T, Chenal-Francisque V, Kucerova Z, Rocha EPC, Nadon C, Grant K, Nielsen EM, Pot B, Gerner-Smidt P, Lecuit M*, Brisse S*
Whole genome-based population biology and epidemiological surveillance of Listeria monocytogenes
Nat Microbiol 2016 Oct 10;2:16185

Maury M, Tsai YH, Charlier C, Touchon M, Chenal-Francisque V, Leclercq A, Criscuolo A, Gaultier C, Roussel S, Brisabois A, Disson O, Rocha E, Brisse S, Lecuit M
Uncovering Listeria monocytogenes hypervirulence by harnessing its biodiversity
Nat Genet 2016 Mar;48(3):308-13

Karlas A, Berre S, Couderc T, Varjak M, Braun P, Meyer M, Gangneux N, Karo-Astover L, Weege F, Raftery M, Schönrich G, Klemm U, Wurzlbauer A, Bracher F, Merits A, Meyer TF, Lecuit M
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs
Nat Commun 2016 May 12;7:11320

Weaver S, Lecuit M
Chikungunya virus and the global spread of a mosquito-borne disease
N Engl J Med 2015 Mar 26;372(13):1231-1239

Gessain G, Tsai YH, Travier L, Bonazzi M, Grayo S, Cossart P, Charlier C, Disson O, Lecuit M
PI3-kinase activation is critical for host barriers permissiveness to Listeria monocytogenes
J Exp Med 2015 Feb 9;212(2):165-83

Blériot C, Dupuis T, Jouvion G, Eberl G. Disson O, Lecuit M
Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection
Immunity 2015 Jan 20;42(1):145-58

Archambaud C, Nahori MA, Soubigou G, Bécavin C, Laval L, Lechat P, Smkvina T, Langella P, Lecuit M*, Cossart P*
Impact of lactobacilli on orally acquired listeriosis
Proc Natl Acad Sci U S A 2012;109(41):16684-9

Nikitas G, Deschamps C, Disson O, Niault T, Cossart P, Lecuit M
Transcytosis of Listeria monocytogenes across the intestinal barrier upon specific targeting of goblet cell accessible E-cadherin
J Exp Med 2011;208(11):2263-77

Tazi A, Disson O, Bellais S, Bouaboud A, Dmytruk N, Dramsi S, Mistou M-Y, Khun H, Mechler C, Tardieux I, Trieu-Cuot P, Lecuit M*, Poyart C*
The surface protein HvgA mediates Group B streptococcus hypervirulence and meningeal tropism in neonates
J Exp Med 2010 Oct 25;207(11):2313-22

Mostowy S, Bonazzi M, Hamon MA, Tham TN, Mallet A, Lelek M, Gouin E, Demangel C, Brosch R, Zimmer C, Sartori A, Kinoshita M, Lecuit M, Cossart P
Entrapment of intracytosolic bacteria by septin cage-like structures
Cell Host Microbe 2010, 010 Nov 18;8(5):433-44

Schilte C, Couderc T, Chrétien F, Sourisseau M, Gangneux N, Guivel-Benhassine F, Gruber A, Tschopp J, Higgs S, Michault A, Arenzana-Seisdedos F, Colonna M, Schwartz O, Lecuit M*, Albert M*
Type I IFN controls chikungunya virus via its action on non-hematopoetic cells
J Exp Med 2010 Feb 15;207(2):429-42

Toledo-Arana A, Dussurget O, Nikitas G, Sesto N, Guet-Revillet H, Balestrino D, Loh E, Gripenland J, Tiensuu T, Vaitkevicius K, Barthelemy M, Vergassola M, Nahori M-A, Soubigou G, Régnault B, Coppée J-Y, Lecuit M, Johansson J, Cossart P
The Listeria transcriptional landscape from saprophytism to virulence
Nature 2009 Jun 18;459(7249):950-6

Disson O, Grayo S, Huillet E, Nikitas G, Langa-Vives F, Dussurget O, Ragon M, Le Monnier A, Babinet C, Cossart P, Lecuit M
Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis
Nature 2008 Oct 23;455(7216):1114-8

Couderc T, Chrétien F, Schilte C, Disson O, Brigitte M, Guivel-Benhassine F, Touret Y, Barau G, Prévost MC, Schuffenecker I, Desprès P, Arenzana-Seisdedos F, Michault A, Albert ML, Lecuit M
A mouse model for Chikungunya infection: young age and inefficient type-I interferon signaling are risk factors for severe disease
PLOS Pathog 2008 4(2): p. e29

Gérardin P, Barau G, Michault A, Bintner M, Randrianaivo H, Choker G, Lenglet Y, Touret Y, Bouveret A, Grivard P, Le Roux K, Blanc S, Schuffenecker I, Couderc T, Arenzana-Seisdedos F, Lecuit M*, Robillard PY*
Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the island of La Réunion
PLOS Medicine 2008. 5(3): p. e60

Lecuit M, Nelson DM, Smith SD, Khun H, Huerre M, Vacher-Lavenu MC, Gordon JI, Cossart P
Targeting and crossing of the human maternofetal barrier by Listeria monocytogenes: role of internalin interaction with trophoblast E-cadherin
Proc Natl Acad Sci U S A 2004 Apr 20;101(16):6152-7

Lecuit M, Abachin E, Martin A, Poyart C, Pochart P, Suarez F, Bengoufa D, Feuillard J, Lavergne A, Gordon JI, Berche P, Guillevin L, Lortholary O
Immunoproliferative small intestinal disease associated with Campylobacter jejuni
N Engl J Med 2004 Jan 15;350(3):239-48

Lecuit M, Vandormael-Pournin S, Lefort J, Huerre M, Gounon P, Dupuy C, Babinet C, Cossart P
A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier
Science 2001 Jun 1;292(5522):1722-5

Lecuit M, Hurme R, Pizarro-Cerda J, Ohayon H, Geiger B, Cossart P
A role for alpha-and beta-catenins in bacterial uptake
Proc Natl Acad Sci U S A 2000 Aug 29;97(18):10008-13

Lecuit M, Dramsi S, Gottardi C, Fedor-Chaiken M, Gumbiner B, Cossart P
A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes
EMBO J 1999 Jul 15;18(14):3956-63