Roman Jerala - Curriculum Vitae#

EDUCATION

• 1986 BSc in chemistry, University of Ljubljana, Slovenia
  
• 1993 PhD in chemistry, University of Ljubljana, Slovenia

CURRENT AND PREVIOUS RESEARCH POSITIONS HELD

• 1994 - 1995 postdoc, University of Virginia, Charlottesville, USA
  
• 1996 – 2001 Laboratory of NMR and molecular modeling at the National Institute of Chemistry (NIC), Ljubljana, Slovenia
  
• Since 2002 head of Department of biotechnology at the National Institute of Chemistry, Ljubljana, Slovenia; full professor at the Faculty of Chemistry and Chemical technology, University of Ljubljana
  
• Since 2009 synthetic biology area director at the Centre of Excellence EN-FIST

SUMMARY OF PUBLICATIONS, PATENTS & INVITATIONS TO INTERNATIONAL MEETINGS

https://scholar.google.si/citations?user=iJXP55QAAAAJ&hl=sl
>150 peer reviewed papers, cited >5500 times, H = 40 Google Scholar; h=32 (WoS));
11 patents, 5 patent applications;
> 70 speaker invitations: GRC (3x), SB6.0 London 2013; International congress on immunology Milan 2013, FEBS3+ Opatija 2013, FNANO Snowbird, 2014, EMBO course SynBio Buenos Aires 2013, Coiled-coils Alpbach 2013, Appl.SynBio Malaga 2013, Bionanotechnology III Cambridge 2012…
Universities: Cambridge, Harvard, Yale, U.Tokyo, U.Osaka, UCSD, U.Mass., U. Heidelberg, U.Vienna, FU.Freiburg, UCLA, U.Trieste, U.Bristol, NTNU Trondheim, MPI Martinsried…

TOPICS OF RESEARCH INTEREST

• Chemical biology - designed bionanostructures based on polypeptides
  
• Synthetic biology: information processing circuits in mammalian cells, medical applications of synthetic biology, DNA-based scaffold for biosynthesis
  
• Molecular mechanism of prion protein conversion
  
• Antimicrobial and endotoxin neutralizing peptides
  
• Proteases and their inhibitors
  
• High resolution NMR spectroscopy of proteins
  

Notable research achievements: invention of new type of protein folds not found in nature (coiled-coil based protein origami), elucidation of the molecular mechanism of activation of TLR4 (by LPS and oxidized phospholipids as endogenous agonists) and TLR3 by dsRNA, the mechanisms on the use of antimalarials for the therapy of autoimmune diseases and designed DNA scaffold based biosynthetic pathway using enzyme-DNA binding domain fusions

Leaver of several national research programs and rpojects
Coordinator of the ERANET project Bioorigami (2014-2017) and partner in ERANET project MediSurf (2016-2019)
Partner in Horizon 2020 MSCA project Tollerant (2015-2018)
Member of COST actions CM1304, CM1306, CA16122.