Michel Goedert - Selected Publications#
My H-index (Web of Science) = 113 (April 23, 2018).
Goedert M, Wischik CM, Crowther RA, Walker JE and Klug A (1988) Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau. Proceedings of the National Academy of Sciences USA 85, 4051-4055.
Goedert M, Spillantini MG, Jakes R, Rutherford D and Crowther RA (1989) Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3, 519-526.
Goedert M, Jakes R, Spillantini MG, Hasegawa M, Smith MJ and Crowther RA (1996) Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature 383, 550-553.
Spillantini MG, Schmidt ML, Lee VMY, Trojanowski JQ, Jakes R and Goedert M (1997) Alpha--Synuclein in Lewy bodies. Nature 388, 839-840.
Spillantini MG, Crowther RA, Jakes R, Hasegawa M and Goedert M (1998) Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proceedings of the National Academy of Sciences USA 95, 6469-6473.
Spillantini MG, Murrell JR, Goedert M, Farlow MR, Klug A and Ghetti B (1998) Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proceedings of the National Academy of Sciences USA 95, 7737-7741.
Goedert M and Spillantini MG (2006) A century of Alzheimer's disease. Science 314, 777-781.
Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M* and Tolnay M (2009) Transmission and spreading of tauopathy in transgenic mouse brain. Nature Cell Biology 11, 909-913. *Equal contributions.
Goedert M (2015) Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled Abeta, tau, and alpha-synuclein. Science 349, 1255555.
Fitzpatrick AWP, Falcon B, He S, Murzin AG, Murshudov G, Garringer HJ, Crowther RA, Ghetti B, Goedert M* and Scheres SHW* (2017) Cryo-EM structures of tau filaments from Alzheimer's disease. Nature 547, 185-190. *Joint supervision of the work.
