Martin Eilers - Selected publications#

• Cannell, I. G., Kong, Y. W., Johnston, S. J., Chen, M. L., Collins, H. M., Dobbyn, H. C., Elia, A., Kress, T. R., Dickens, M., Clemens, M. J., Heery, D. M., Gaestel, M., Eilers, M., Willis, A. E., and Bushell, M. (2010). p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication. PNAS, 107, 5375-80.

• Iraci, N. Diolaiti, D., Papa, A., Porro, A., Valli, E., Gherardi, S., Herold, S., Eilers, M., Haber, M., Norris, M., Bernardoni, R., Della Valle, G., and Perini, G. (2010). A Sp1/Miz1/MycN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF. Cancer Res, Dec 1.

• Herkert, B., Dwertmann, A., Herold, S., Naud, J. F.,Finkernagel, F., Harms, G. S., Wanzel, M., and Eilers, M. (2010). The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis. J Cell Biol, 188 (6), 905-18.

• Herkert, B.,and Eilers, M. (2010). Trans-criptional Repression: the dark side of Myc. Genes and Cancer, 1, 580-86.

• Kosan, C., Saba, I., Godmann, M., Herold, S., Herkert, B., Eilers, M., and Möröy, T. (2010). Transcription factor miz-1 is required to regulate interleukin-7 receptor signaling at early commitment stages of B cell differentiation. Immunity, 33, 917-28.

• Müller, J., Samans, B., van Riggelen, J., Fagà, G., Peh, R., Wei, C. L., Müller, H., Amati, B., Felsher, D., and Eilers, M. (2010). TGF beta-dependent gene expression shows that senescence correlates with abortive differentiation along several lineages in Myc-induced lymphomas. Cell Cycle, 9, 4622-26.

• Popov, N., Schülein, C., Jaenicke, L. and Eilers, M. (2010). Ubiquitylation of the amino-terminus of Myc by SCF (beta-TrCP) antagonizes SCF (Fbw7)-mediated degradation. Nat Cell Biol, 12, 973-81.

• Schlereth, K., Beinoraviciute-Kellner, R., Zeitlinger, M. K., Bretz, A.C., Sauer, M., Charles, J. P., Vogiatzi, F., Leich, E., Samans, B., Eilers, M., Kisker, C., Rosenwald, A., and Stiewe, T. (2010). DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell, 14, 356-68.

• Singh, G., Singh, S. K., König, A., Reutlinger, K., Nye, M. D., Adhikary, T., Eilers, M., Gress, T. M., Fernandez-Zapico, M. E., and Ellenrieder, V. (2010). Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation. J Biol Chemistry, 285, 27241-50.

• Teutschbein, J., Haydn, J. M., Samans, B., Krause, M., Eilers, M., Schartl, M., and Meierjohann S. (2010). Gene expression analysis after receptor tyrosine kinase activation reveals new potential melanoma proteins. BMC Cancer, 10, 386.

• van Riggelen, J., Müller, J., Otto, T., Beuger, V., Samans, B., Yetil, A., Tao, J., Choi, P., Kosan, C., Möröy, T., Felsher, D., and Eilers, M. (2010). The interaction between Myc and Miz1 is required to antagonize TGF beta- dependent atutocrine signaling during lymphoma formation and maintenance. Gene Dev, 24, 1281-94.