Christine Stabell Benn - Publications#


A total of 288 peer-reviewed articles. H-index 41.

The 10 most important articles:

Benn CS, Netea MG, Selin LK, Aaby P. A small jab – a big effect: nonspecific immunomodulation by vaccines. Trends Immunol 2013. (A major review, linking the epidemiological and immunological evidence for non-specific effects of vaccines).

Sørup S, Benn CS, Poulsen A, Krause TG, Aaby P, Ravn H. Live vaccine against measles, mumps, and rubella and the risk of hospital admissions for nontargeted infections. JAMA 2014. (Taking the findings of non-specific effects of vaccine from Africa back to testing in Denmark).

Benn CS, Aaby P, Arts RJ, Jensen KJ, Netea MG, Fisker AB. An enigma: why vitamin A supplementation does not always reduce mortality even though vitamin A deficiency is associated with increased mortality. Int J Epidemiol 2015. (A major review, challenging the current assumption that vitamin A works by preventing vitamin A deficiency).

Biering-Sørensen S, Aaby P, Lund N, Monteiro I, Jensen K, Eriksen HB, Schaltz-Buchholzer F, Jørgensen ASP, Rodrigues A, Fisker AB, Benn CS. Early BCG and neonatal mortality among low-birth-weight infants: A randomised controlled trial. Clin Inf Dis 2017. (An example of how we have conducted large-scale randomised trials of vaccines in Africa).

Arts RJW, Moorlag SJCFM, Novakovic B, Li Y, Wang SY, Oosting M, Kumar V, Xavier RJ, Wijmenga C, Joosten LAB, Reusken CBEM, Benn CS, Aaby P, Koopmans MP, Stunnenberg HG, van Crevel R, Netea MG. BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity. Cell Host Microbe 2018. (An example of how we have bridged to immunology, exploring the mechanisms underlying non-specific effects of vaccines).

Stensballe LG, Ravn H, Birk NM, Kjærgaard J, Nissen TN, Pihl GT, Thøstesen LM, Greisen G, Jeppesen DL, Kofoed PE, Pryds O, Sørup S, Aaby P, Benn CS. BCG Vaccination at Birth and Rate of Hospitalization for Infection Until 15 Months of Age in Danish Children: A Randomized Clinical Multicenter Trial. J Pediatric Infect Dis Soc. 2018. (Testing non-specific effects of vaccines in a large-scale randomised controlled trial in Denmark).

Benn CS, Fisker AB, Rieckmann A, Jensen AKG, Aaby P. How to evaluate potential non-specific effects of vaccines: the quest for randomized trials or time for triangulation? Expert Rev Vaccines. 2018. (An example of how we developed new analytical tools for the assessment of non-specific effects of vaccines in epidemiological studies).

Benn CS. Early neonatal vitamin A supplementation and infant mortality: two alternative hypotheses. Arch Dis Child. 2020 (An example of how we, based on data and triangulation, challenged the idea that a global policy of providing neonatal vitamin A supplementation, would improve infant survival).

Aaby P, Fisker AB, Björkman A, Benn CS. WHO's rollout of malaria vaccine in Africa: can safety questions be answered after only 24 months? BMJ. 2020 (Asking critical data-driven questions regarding WHO's vaccine roll-out in Africa).

Benn CS, Fisker AB, Sørup S, Rieckmann A, Aaby P. Vaccinology: Time to change paradigm? Lancet Infect Dis, 2020 (a major review, covering decades of vaccine research and proposing a new paradigm for vaccines).

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