Matthias Barton - Selected Publications#

E.R. Prossnitz, M. Barton. The G protein-coupled estrogen receptor GPER in health and disease - an update
Nat Rev Endocrinol, 19, 407-424, 2023

A. Cignarella, C. Boscaro, M. Albiero, C. Bolego, M. Barton. Post-transcriptional and epigenetic regulation of estrogen signaling
J Pharm Exp Ther 386, 288–297, 2023

G.P. Rossi, M. Barton, N. Dhaun, D. Rizzoni, T.M. Seccia. Consensus Document: Challenges in the evaluation of endothelial cell dysfunction: a statement from the European Society of Hypertension Working Group on Endothelin and Endothelial Factors
J Hypertens, 41, 969-979, 2023

M. Barton. Endothelium and endothelin: regulators of arterial stiffness and fibrinolysis in ANCA-associated vasculitis
Kidney Int 102, 963–966, 2022

A. Cignarella, G.P. Fandini, C. Bolego, L. Trevisi, C. Boscaro, V. Sanga, T. M. Seccia, A. Rosato, G.P. Rossi, M. Barton. Clinical efficacy and safety of angiogenesis inhibitors: sex differences and current challenge
Cardiovasc Res 118, 988-1003, 2022

M. Barton, C. Cardillo. Exercise is medicine - key to cardiovascular disease and diabetes prevention
Cardiovasc Res 117, 360-363, 2021

N. Emoto, M. Yanagisawa, M. Barton. In memoriam: Tomoh Masaki
Hypertension 76, 1664-1666, 2020

G.P. Rossi, V. Sanga, M. Barton. Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients
eLife 9, e57278, 2020

M. Barton, Meyer M.R. Heart failure with preserved ejection fraction in women: new clues to causes and treatment
JACC Basic Transl Sci 5, 296-299, 2020

M. Barton, E.R. Prossnitz. Early life stress impairs insulin signaling in adulthood
J Physiol 598, 427-428, 2020

R.M. Gupta, P. Libby, M. Barton. Linking regulation of nitric oxide to endothelin-1: the Yin and Yang of vascular tone in the atherosclerotic plaque
Atherosclerosis 292, 201-203, 2020

M. Barton, Cardillo C. In memoriam: Paul M. Vanhoutte
J Physiol 597, 5731-5737, 2019

M. Barton, M.R. Meyer, E.R. Prossnitz. Nox1 downregulators: A new class of therapeutics
Steroids 152, 108494, 2019

M. Barton, M.R. Meyer, E.R. Prossnitz. Potential role for Nox1 for endothelin-induced brain capillary vasoconstriction in Alzheimer's disease and dementia
Science 365, eaav9518, 2019

M. Barton, M. Yanagisawa. Endothelin - 30 years from discovery to therapy
Hypertension 74, 1232-1265, 2019

Barton M. Self-experimentation and serendipity: how cardiac catheterization led the way to coronary balloon angioplasty
BMJ 363, k5006, 2018

M. Barton, M.R. Meyer. HuR-ry up: how hydrogen sulfide protects against atherosclerosis
Circulation 139:115–118, 2019

M. Barton, M. R. Meyer. Permissive role for GPER in arterial hypertension.
Hypertension 73, e9–e10, 2019

M. Barton. Primun non nocere: why hormone treatment with calcitriol («Vitamin» D) is not a magic bullet
Arterioscler Thromb Vasc Biol 39, 117–120, 2019

G.P. Rossi, Secchia TM, M. Barton. A.H. Danser, P. de Leeuw, N. Dhaun, D. Rizzoni, P. Rossignol, L.M. Ruilope, A.H. van den Meiracker, D.J. Webb. Endothelial factors in the pathogenesis and treatment of chronic kidney disease Part I: General mechanisms. A joint consensus statement from the ESH Working Group on Endothelin and Endothelial Factors and the Japanese Society of Hypertension
J Hypertens 36, 451–461, 2018

G.P. Rossi, Secchia TM, M. Barton. A.H. Danser, P. de Leeuw, N. Dhaun, D. Rizzoni, P. Rossignol, L.M. Ruilope, A.H. van den Meiracker, S. Ito, N. Hasebe, D.J. Webb. Endothelial factors in the pathogenesis and treatment of chronic kidney disease Part II: Role in Disease Conditions. A joint consensus statement from the ESH Working Group on Endothelin and Endothelial Factors and the Japanese Society of Hypertension
J Hypertens 36, 462–471, 2018

M. Barton, E. Filardo, S. Lolait, P. Thomas, M. Maggiolini, E.R. Prossnitz. Twenty years of G protein-coupled estrogen receptor GPER: historical and personal perspectives
J Steroid Biochem Mol Biol 176, 4–15, 2018

M. Barton, E.R. Prossnitz. Rapid vasodilation to raloxifene: role of estrogen receptors and off-target effects
Br J Pharmacol 174, 4201–4202, 2017

B. Caroccia, T.M. Seccia, M. Barton, G.P. Rossi. Estrogen signaling in the adrenal cortex: implications for blood pressure sex differences.
Hypertension 86, 840–848, 2016

M. Barton, M. Husmann. Obesity causes lymphatic vascular injury: time for clinical translation
J Physiol 594, 6807–6808, 2016

M.R. Meyer, M. Barton. GPER blockers as Nox downregulators: A new drug class to target chronic non-communicable diseases.
Journal of Steroid Biochemistry and Molecular Biology 176, 82–87, 2018

M. Barton, E.J. Filardo, S.J. Lolait, P. Thomas, M. Maggiolini, E.R. Prossnitz. Twenty years of the G protein-coupled estrogen receptor GPER: Historical and personal perspectives.
J Steroid Biochem Mol Biol. 176, 4–15, 2018

M. Barton, M. Husmann, M.R. Meyer.Accelerated vascular aging as a paradigm for hypertensive vascular disease: prevention and therapy.
Canadian Journal of Cardiology 32, 680-686, 2016

M.R. Meyer, N.C. Fredette, C. Daniel, G. Sharma, K. Amann, J.B. Arterburn, M. Barton, E.R. Prossnitz. Obligatory role for GPER in cardiovascular aging and disease.
Science Signaling 9, ra105, 2016

M. Barton, M.R. Meyer. Nicolaus Copernicus and the rapid vascular responses to aldosterone.
Trends in Endocrinology and Metabolism 26, 396-398, 2015

M. Barton, E.R. Prossnitz. Emerging roles of GPER in diabetes and atherosclerosis.
Trends in Endocrinology and Metabolism 26, 185-192, 2015

M.R. Meyer, N.C. Fredette, T.A. Howard, C. Hu, C. Ramesh, C. Daniel, K. Ammann, J.B. Arterburn, M. Barton, E.R. Prossnitz. G protein-coupled estrogen receptor protects from atherosclerosis.
Scientific Reports 4, 7564, 2014

D.E. Kohan, M. Barton. Endothelin and endothelin antagonists in chronic kidney disease.
Kidney International 86, 896-904, 2014

M.R. Meyer, N.C. Fredette, M. Barton, E.R. Prossnitz. Regulation of vascular smooth muscle tone by Adipose-Derived Contracting Factor.
PLoS ONE 8, e79245, 2013

M. Barton. Prevention and endothelial therapy of coronary artery disease.
Current Opinion in Pharmacology 13, 225-241, 2013

M. Barton. Cholesterol and atherosclerosis: Modulation by estrogen.
Current Opinion in Lipidology 24, 214-220, 2013

E.R. Prossnitz, M. Barton. The G protein-coupled estrogen receptor GPER in physiology and disease.
Nature Reviews Endocrinology 7, 715-726, 2011

M. Barton, M.R. Meyer, J.L. Bolton, E.R.Prossnitz. Lung cancer and hormone replacement therapy.
Lancet 375 (9709), 117-118, 2010

E. Haas, I. Bhattacharya, E. Brailoiu, M. Damjanovic, G.C. Brailoiu, X. Gao, L. MuellerGuerre, A. Gut, R. Minotti, M.R. Meyer, K. Amann, E. Ammann, A. PerezDominguez, M. Genoni, D.J. Clegg, N.J. Dun, T.C. Resta, E.R. Prossnitz, M. Barton. Regulatory role of G protein coupled estrogen receptor for vascular function and obesity
Circulation Research 104, 288-291, 2009

M. Barton. Reversal of proteinuric renal disease and the emerging role of endothelin.
Nature Reviews Nephrology 4, 490-501, 2008

M. Barton, R.K. Dubey. Postmenopausal hormone-replacement therapy.
New Engl J Med 346, 63-65, 2002

M. Barton, C.C. Haudenschild, L.V. d'Uscio, S. Shaw, K. Münter, T.F. Luscher. Endothelin ETA receptor blockade restores NO-mediated endothelial dysfunction and inhibits atherosclerosis in apoE-deficient mice.
Proc Natl Acad Sci USA 95, 14367-14372, 1998

M. Barton, T.F. Lüscher, T. J. Rabelink. Salt Wars (On the “political” science of salt). Science 281, 1961-1963, 1998

M.R. Tschudi, M. Barton, N.A. Bersinger, P. Moreau, F. Cosentino, G. Noll, T. Malinski, T.F. Luscher. Effect of age on kinetics of nitric oxide release in rat aorta and pulmonary artery.
J Clin Invest 98, 899-905,1996

A. Mugge, M. Riedel, M. Barton, M. Kuhn M, P.R. Lichtlen. Endothelium independent relaxation of human coronary arteries by 17 beta-oestradiol in vitro.
Cardiovasc Res 27, 1939-1942, 1993