Archana Singh-Manoux#

Laudatio by Johannes Siegrist#

Archana Singh-Manoux is a social psychologist and epidemiologist trained in India and in France. In 2000 she was offered a prominent position as Senior Research Fellow at the Department of Epidemiology and Public Health, University College of London and, in 2005, she received a ‘Chaire d’Excellence’ in combination with a tenured position at INSERM in Paris. In 2006, Dr. Singh-Manoux was awarded a 'European Young Investigator Award' (EURYI) by the European Science Foundation, complemented more recently by two substantial research grants from the National Institute of Ageing, USA. She is currently a principal investigator a co-investigator in internationally leading epidemiological cohort studies, in particular the British Whitehall II-Study and the French GAZEL Study. In addition to her extensive research activity she is involved in a European Master of Gerontology programme, in a French Doctoral School in Public Health, and in a number of professional organizations including the MacArthur Research Network on Socioeconomic Status and Health, USA.

Dr. Singh-Manoux's research on cognitive ageing has received international recognition in recent years. She was among the first to demonstrate social and behavioural determinants of cognitive ageing in a life course perspective, applying innovative measures to large cohort studies, specifically the Whitehall II and the GAZEL study. More specifically, she studied the association of behavioural cardiovascular risk factors, biomedical factors (inflammation, heart rate variability, HDL-cholesterol) and sub—clinical coronary heart disease with impaired cognitive functioning in midlife, thus opening a new perspective on early invention of risks of cognitive decline in old age.

A second major research contribution of Dr. Singh-Manoux concerns the study of socioeconomic determinants of health in midlife where she applied the concept of ‘subjective social status‘ in addition to established sociological indicators to improve the power of predicting morbidity und mortality risks. She also demonstrated evidence on the limited statistical contribution of intelligence towards explaining the social gradient of mortality. In a related third area of research, Dr, Singh-Manoux elucidated the role of adverse psychosocial factors at work and at home in explaining cardiovascular morbidity, for instance in her most frequently cited paper with Hannah Kuper and co-authors on failed reciprocity at work or in a paper on limited control at home.

Dr. Singh-Manoux is a very promising, highly motivated young researcher with a truly European commitment, working simultaneously in France and in the United Kingdom and guiding collaborative research with international impact. In the last ten years she has been impressively productive in contributing to more than 80 papers whose majority was published in leading international journals. And even so, her publication and citation impact has witnessed a steep increase in 2008 and 2009.

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