Botond Roska - Selected Publications#
Cameron S. Cowan, Magdalena Renner, Martina De Gennaro, Brigitte Gross-Scherf, David Goldblum, Yanyan Hou, Martin Munz, Tiago M. Rodrigues, Jacek Krol, Tamas Szikra, Rachel Cuttat, Annick Waldt, Panagiotis Papasaikas, Roland Diggelmann, Claudia P. Patino-Alvarez, Patricia Galliker, Stefan E. Spirig, Dinko Pavlinic, Nadine Gerber-Hollbach, Sven Schuierer, Aldin Srdanovic, Marton Balogh, Riccardo Panero, Akos Kusnyerik, Arnold Szabo, Michael B. Stadler, Selim Orgül, Simone Picelli, Pascal W. Hasler, Andreas Hierlemann, Hendrik P. N. Scholl, Guglielmo Roma*, Florian Nigsch*, Botond Roska* Cell types of the human retina and its organoids at single-cell resolution(*shared corresponding authors). Cell. 2020. In Press
Nelidova D, Morikawa RK, Cowan CS, Raics Z, Goldblum D, Scholl H, Szikra T, Szabo A, Hillier D*, Roska B* Restoring light sensitivity using tunable near-infrared sensors (*shared corresponding authors) Science. 2020 Jun 5;368(6495):1108-1113
Jüttner J, Szabo A, Gross-Scherf B, Morikawa R, Rompani S, Hantz P, Szikra T, Esposti E, Cowan C, Bharioke A, Patino-Alvarez C, Keles Ö, Kusnyerik A, Azoulay T, Hartl D, Krebs A, Schübeler D, Hajdu R, Lukats A, Nemeth J, Nagy Z, Wu KC, Wu RH, Xiang L, Fang XL, Jin ZB, Goldblum D, Hasler P, Scholl H, Krol J*, Roska B* Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates, and humans (*shared corresponding authors) Nature Neuroscience 2019. Aug;22(8):1345-1356
Macé E, Montaldo G, Trenholm S, Cowan C, Brignall A, Urban, Roska B Whole-brain functional ultrasound imaging reveals brain modules for visuomotor integration. Neuron. 2018 100(5):1241-1251
Drinnenberg A, Franke F, Morikawa RK, Jüttner J, Hillier D, Hantz P, Hierlemann A, da Silveira RA*, Roska B* How diverse retinal functions arise from feedback at the first visual synapse. (*shared corresponding authors) Neuron. 2018. Jul 11;99(1):117-134
Schubert R, Trenholm S, Balint K, Kosche G, Cowan CS, Mohr MA, Munz M, Martinez-Martin D, Fläschner G, Newton R, Krol J, Scherf BG, Yonehara K, Wertz A, Ponti A, Ghanem A, Hillier D, Conzelmann KK, Müller DJ*, Roska B*. Virus stamping for targeted single-cell infection in vitro and in vivo. (*shared corresponding authors) Nature Biotechnology 2018 Jan;36(1):81-88
Hillier D, Fiscella M, Drinnenberg A, Trenholm S, Rompani SB, Raics Z, Katona G, Juettner J, Hierlemann A, Rozsa B, Roska B. Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex. Nature Neuroscience 2017 Jul;20(7):960-968
Rompani SB, Müllner FE, Wanner A, Zhang C, Roth CN, Yonehara K, Roska B. (2017). Different Modes of Visual Integration in the Lateral Geniculate Nucleus Revealed by Single-Cell-Initiated Transsynaptic Tracing. Neuron. 2017 Feb 22;93(4):767-776
Yonehara K, Fiscella M, Drinnenberg A, Esposti F, Trenholm S, Krol J, Franke F, Scherf BG, Kusnyerik A, Müller J, Szabo A, Jüttner J, Cordoba F, Reddy AP, Németh J, Nagy ZZ, Munier F, Hierlemann A, Roska B. Congenital Nystagmus Gene FRMD7 Is Necessary for Establishing a Neuronal Circuit Asymmetry for Direction Selectivity. Neuron. 2016 Jan 6;89(1):177-93.
Wertz A, Trenholm S, Yonehara K, Hillier D, Raics D, Leinweber M, Szalay G, Ghanem A, Keller G, Rózsa B, Conzelmann KK, Roska B. Single-cell-initiated Monosynaptic Tracing Reveals Layer-specific Cortical Network Modules. Science. 2015, 349 (6243):70-4
Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B* and Filipowicz W*. A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. (*shared corresponding authors) Nature Communications 2015 Jun 4;6:7305.
Szikra T, Trenholm S, Drinnenberg A, Juettner J, Raics Z, Farrow K, Biel M, Awatramani G, Clark D, Sahel JA, da Silveira RA, Roska B Rods in daylight act as relay cells for cone-driven horizontal cell-mediated surround inhibition to downstream visual circuits. Nature Neuroscience. 2014, 17(12):1728-35
Busskamp V, Krol J, Nelidova D, Daum J, Szikra T, Tsuda B, Juettner J, Farrow K, Gross Scherf B, Patino Alvarez CP, Genoud C, Sothilingam V, Tanimoto N, Stadler M, Seeliger M, Stoffel M, Filipowicz W*, Roska B* MiRNAs 182 and 183 are necessary to maintain adult cone photoreceptor outer segments and visual function (*shared corresponding authors) Neuron. 2014, 83(3):586-600
Yonehara K, Farrow K, Ghanem A, Hillier D, Balint K, Teixeira M, Jüttner J, Noda M, Neve R, Conzelmann KK, Roska B. The first stage of cardinal direction selectivity is localized to the dendrites of retinal ganglion cells. Neuron. 2013, 79(6):1078-85
Farrow K, Teixeira M, Szikra T, Juettner J, Viney JT, Balint K, Yonehara K, Roska B. Ambient illumination toggles a neuronal circuit switch in the retina and visual perception at cone threshold Neuron. 2013, 78, 1–14
Siegert S, Cabuy E, Gross Scherf B, Kohler H, Panda A, Le YZ, Fehling HJ, Gaidatzis DG, Stadler MB, Roska B. Transcriptional code and disease map for adult retinal cell types. Nature Neuroscience. 2012 Jan 22;15(3):487-95
Yonehara K, Balint K, Noda M, Nagel G, Bamberg E, Roska B. Spatially asymmetric reorganization of inhibition establishes a motion-sensitive circuit. Nature. 2011, 469(7330):407-10
Busskamp V, Duebel J, Balya D, Fradot M, Viney TJ, Siegert S, Groner AC, Cabuy E, Forster V, Seeliger M, Biel M, Humphries P, Paques M, Mohand-Said S, Trono D, Deisseroth K, Sahel JA, Picaud S, Roska B. Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa. Science. 2010, 329(5990):413-7.
Krol J, Busskamp V, Markiewicz I, Stadler MB, Ribi S, Duebel J, Oertner TO, Schübeler D, Schratt G, Fehling HJ, Richter J, Bibel M, Roska B* and Filipowicz W*. Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs. (*shared corresponding authors) Cell. 2010,141(4):618-31.
Münch TA, da Silveira RA, Siegert S, Viney TJ, Awatramani GB, Roska B. Approach sensitivity in the retina processed by a multifunctional neural circuit. Nature Neuroscience. 2009 Oct; 12(10):1308-16.
Siegert S, Scherf BG, Del Punta K, Didkovsky N, Heintz N, Roska B. Genetic address book for retinal cell types. Nature Neuroscience. 2009 Sep; 12(9):1197-204.
Boldogkoi Z, Balint K, Awatramani GB, Balya D, Busskamp V, Viney TJ, Lagali PS, Duebel J, Pásti E, Tombácz D, Tóth JS, Takács IF, Scherf BG, Roska B. Genetically timed, activity-sensor and rainbow transsynaptic viral tools. Nature Methods. 2009 Feb; 6(2):127-30.
Lagali PS, Balya D, Awatramani GB, Münch TA, Kim DS, Busskamp V, Cepko CL, Roska B. Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration. Nature Neuroscience. 2008 Jun; 11(6):667-75.
Viney TJ, Balint K, Hillier D, Siegert S, Boldogkoi Z, Enquist LW, Meister M, Cepko CL, Roska B. Local retinal circuits of melanopsin-containing ganglion cells identified by transsynaptic viral tracing. Curr Biol. 2007 Jun 5;17(11):981-8.
Roska B, Werblin F. Rapid global shifts in natural scenes block spiking in specific ganglion cell types. Nature Neuroscience. 2003 Jun; 6(6):600-8.
Roska B, Werblin F. Vertical interactions across ten parallel, stacked representations in the mammalian retina. Nature. 2001 Mar 29; 410(6828):583-7.
