Hugh R.B. Pelham - List of Publications#

1. Pelham, H.R.B. and Jackson, R.J. (1976) An efficient mRNA-dependent translation system from reticulocyte lysates. Eur. J. Biochem. 67, 247-256.

2. Pelham, H.R.B. and Stuik, E.J. (1977) Translation of Cowpea Mosaic virus RNA in a messenger dependent cell free system from rabbit reticulocytes. Colloques Internationaux C.N.R.S. 261, 691-695.

3. Pelham, H.R.B. (1977) Use of coupled transcription and translation to study mRNA production by vaccinia cores. Nature 269, 532-534.

4. Pelham, H.R.B., Sykes, J.M.M. and Hunt, T. (1978) Characteristics of a coupled cell-free transcription and translation system directed by vaccinia cores. Eur. J. Biochem. 82, 199-209.

5. Harper, J.M.M., Parsonage, M.T., Pelham, H.R.B. and Darby, G. (1978) Heat inactivation of vaccinia virus particle-associated functions: properties of heated particles in vivo and in vitro. J. Virol. 26, 646-659.

6. Pelham, H.R.B. (1978) Leaky UAG termination codon in Tobacco Mosaic virus RNA. Nature 272, 469-471.

7. Pelham, H.R.B. (1978) Translation of encephalomyocarditis virus RNA in vitro yields an active proteolytic processing enzyme. Eur. J. Biochem 85, 457-462.

8. Pelham, H.R.B. (1979) Translation of fragmented viral RNA in vitro: initiation at multiple sites. FEBS Lett. 100, 195-199.

9. Pelham, H.R.B. (1979) Synthesis and proteolytic processing of Cowpea Mosaic virus proteins in reticulocyte lysates. Virology 96, 463-477.

10. Pelham, H.R.B. (1979) Translation of Tobacco Rattle virus RNAs in vitro: four proteins from three RNAs. Virology 97, 256-265.

11. Braude, P.R. and Pelham, H.R.B. (1979) A microsystem for the extraction and in-vitro translation of mouse embryo mRNA. J. Reprod. Fert. 56, 153-158.

12. Braude, P., Pelham, H., Flach, G. and Lobatto, R. (1979) Post-transcriptional control in the early mouse embryo. Nature 282, 102-105.

13. Pelham, H.R.B. and Brown, D.D. (1980) A specific transcription factor that can bind either the 5S RNA gene or 5S RNA. Proc. Natl. Acad. Sci. U.S.A. 77, 4170-4174.

14. Schultz, G.A., Clough, J.R., Braude, P.R., Pelham, H.R.B. and Johnson, M.H. (1981) A re-examination of messenger RNA populations in the pre-implantation mouse embryo. In "Cellular and Molecular Aspects of Implantation" (S. Glesser and D. Bullock, eds) Plenum Press, pp 137-154.

15. Pelham, H.R.B., Wormington, W.M. and Brown, D.D. (1981) Related 5S RNA transcription factors in Xenopus oocytes and somatic cells. Proc. Natl. Acad. Sci. U.S.A. 78, 1760-1764.

16. Pelham, H.R.B., Bogenhagen, D.F., Sakonju, S., Wormington, W.M. and Brown, D.D. (1981) Studies on the developmental control of 5S RNA gene expression. In "Developmental Biology Using Purified Genes" (D. Brown, ed) ICN-UCLA Symposia on Molecular and Cellular Biology, vol 23, Academic Press, New York, pp 447-461.

17. Pelham, H.R.B. (1982) Techniques for eucaryotic protein synthesis in vitro. Techniques in the Life Sciences, part B418, Elsevier/North-Holland, 18 pp.

18. Pelham, H.R.B. and Bienz, M. (1982) DNA sequences required for transcriptional regulation of the Drosophila hsp70 heat-shock gene in monkey cells and Xenopus oocytes. In "Heat Shock from Bacteria to Man" (M. Schlesinger, M. Ashburner and A. Tissieres, eds) Cold Spring Harbor Press, New York, pp 43-48.

19. Pelham, H.R.B. (1982) A regulatory upstream promoter element in the Drosophila hsp70 heat shock gene. Cell 30, 517-528.

20. Pelham, H.R.B. and Bienz, M. (1982) A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase gene. EMBO J. 1, 1473-1477.

21. Bienz, M. and Pelham, H.R.B. (1982) Expression of a Drosophila heat-shock protein in Xenopus oocytes: conserved and divergent regulatory signals. EMBO J. 1, 1583-1588.

22. Mace, H.A.F., Pelham, H.R.B. and Travers, A.A. (1983) Association of an S1 nuclease-sensitive structure with short direct repeats 5' of Drosophila heat shock genes. Nature 304, 555-557.

23. Pelham, H.R.B. and Lewis, M.J. (1983) Assay of natural and synthetic heat-shock promoters in monkey COS cells: requirements for regulation. In "Gene Expression" (D. Hamer and M. Rosenberg, eds) UCLA Symposia on Molecular and Cellular Biology, New series, vol 8, Alan R. Liss, New York, pp 75-85.

24. Pelham, H.R.B. (1983) A regulatory heat-shock promoter element. In "Enhancers and Eucaryotic Gene Expression" (Y. Gluzman and T. Shenk, eds) Cold Spring Harbor Laboratory, New York, pp 175-179.

25. Bonner, J.J., Parks, C., Parker-Thornberg, J., Mortin, M.A. and Pelham, H.R.B. (1984) The use of promoter fusions in Drosophila genetics: isolation of mutations affecting the heat shock response. Cell 37, 979-991.

26. Pelham, H., Lewis M. and Lindquist, S. (1984) Expression of a Drosophila heat shock protein in mammalian cells: transient association with nucleoli after heat shock. Phil. Trans. R. Soc. Lond. B 307, 301-307.

27. Munro, S. and Pelham, H.R.B. (1984) Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp70. EMBO J. 3, 3087-3093.

28. Pelham, H.R.B. (1984) Hsp70 accelerates the recovery of nucleolar morphology after heat shock. EMBO J. 3, 3095-3100.

29. Pelham, H.R.B. (1984) The control of gene expression in response to cellular stress. In the proceedings of the Japan Medical Research Foundation's 3rd seminar on recombinant DNA, pp155-176 (translated into Japanese).

30. Pelham, H. (1985) Activation of heat-shock genes in eucaryotes. Trends Genet. 1, 31-35.

31. Pelham, H., Lewis, M. and Munro, S. (1985) A nucleolar function for mammalian and Drosophila 70kD heat shock proteins. In "Sequence Specificity in Transcription and Translation" (eds. R. Calendar and L. Gold), pp 681-688, Alan R. Liss, Inc, New York.

32. Morganelli, C.M., Berger, E.M. and Pelham, H.R.B. (1985) Transcription of Drosophila small hsp-tk hybrid genes is induced by heat shock and by ecdysterone in transfected Drosophila cells. Proc. Natl. Acad. Sci. U.S.A. 82, 5865-5869.

33. Munro, S. and Pelham, H.R.B. (1985) What turns on heat shock genes? Nature 317, 477-478.

34. Chia, W., Savakis, C., Karp, R., Pelham, H. and Ashburner, M. (1985) Mutation of the Adh gene of Drosophila melanogaster containing an internal tandem duplication. J. Mol. Biol. 186, 679-688.

35. Lewis, M.J. and Pelham, H.R.B. (1985) Involvement of ATP in the nuclear and nucleolar functions of the 70 kd heat shock protein. EMBO J. 4, 3137-3143.

36. Bienz, M. and Pelham, H.R.B. (1986) Heat shock regulatory elements function as an inducible enhancer in the Xenopus hsp70 gene and when linked to a heterologous promoter. Cell 45, 753-760.

37. Riddihough, G. and Pelham, H.R.B. (1986) Activation of the Drosophila hsp27 promoter by heat and by ecdysone involves independent and remote regulatory elements. EMBO J. 5, 1653-1658.

38. Munro, S. and Pelham, H.R.B. (1986) An hsp70-like protein in the ER: identity with the 78kD glucose regulated protein and immunoglobulin heavy chain binding protein. Cell 46, 291-300.

39. Pelham, H.R.B. (1986) Speculations on the functions of the major heat shock and glucose-regulated proteins. Cell 46, 959-961.

40. Sorger, P.K. and Pelham. H.R.B. (1987) The glucose-regulated protein grp94 is related to heat shock protein hsp90. J. Mol. Biol. 194, 341-344.

41. Bienz, M. and Pelham, H.R.B. (1987) Mechanisms of heat shock gene activation in higher eucaryotes. Advances in Genetics 24, 31-72.

42. Pelham, H.R.B. (1987) Properties and uses of heat shock promoters. In "Genetic Engineering: Principles and Methods" (J.K. Setlow, ed), vol. 9, pp. 27-44. Plenum Press, New York.

43. Munro, S. and Pelham, H.R.B. (1987) A C-terminal signal prevents secretion of luminal ER proteins. Cell 48, 899-907.

44. Sorger, P.K. and Pelham, H.R.B. (1987) Cloning and expression of a gene encoding hsc73, the major hsp70-like protein in unstressed rat cells. EMBO J. 6, 993-998.

45. Sorger, P.K., Lewis, M.J. and Pelham, H.R.B. (1987) Heat shock factor is regulated differently in yeast and HeLa cells. Nature 329, 81-84.

46. Sorger, P.K. and Pelham, H.R.B. (1987) Purification and characterization of a heat shock element binding protein from yeast. EMBO J. 6, 3035-3041.

47. Riddihough, G. and Pelham, H.R.B. (1987) An ecdysone response element in the Drosophila hsp27 promoter. EMBO J. 6, 3729-3734.

48. Pelham, H.R.B. (1988) Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment. EMBO J. 7, 913-918.

49. Pelham, H.R.B. (1988) Heat shock proteins: coming in from the cold. Nature 332, 776-777.

50. Pelham, H.R.B., Hardwick, K.G. and Lewis, M.J. (1988) Sorting of soluble ER proteins in yeast. EMBO J. 7, 1757-1762.

51. Zimmermann, R., Sagstetter, M., Lewis, M.J. and Pelham, H.R.B. (1988) 70kd heat shock proteins and an additional component from reticulocyte lysate stimulate import of M13 procoat protein into microsomes. EMBO J. 7, 2875-2880.

52. Sorger, P.K. and Pelham, H.R.B. (1988) Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation. Cell 54, 855-864.

53. Jakobsen, B.K. and Pelham, H.R.B. (1988) Constitutive binding of yeast heat shock factor to DNA in vivo. Mol. Cell. Biol. 8, 5040-5042.

54. Pelham, H.R.B. (1989) The selectivity of secretion: protein sorting in the endoplasmic reticulum. Biochem. Soc. Trans. 17, 795-802.

55. Pelham, H.R.B. (1989) Heat shock and the sorting of luminal ER proteins. EMBO J. 8, 3171-3176.

56. Pelham, H.R.B. (1989) Control of protein exit from the endoplasmic reticulum. Ann. Rev. Cell Biol. 5, 1-23.

57. Pelham, H.R.B. (1989) The sorting of resident ER proteins from secreted proteins. Proceedings of The Robert A. Welch Foundation Conference on Chemical Research XXXIII Membrane Proteins: Targeting and Transduction, pp. 35-50.

58. Hardwick, K.G., Lewis, M.J., Semenza, J., Dean, N. and Pelham, H.R.B. (1990) ERD1, a yeast gene required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus. EMBO J. 9, 623-630.

59. Pelham, H.R.B. (1990) Functions of the hsp70 protein family: an overview. In "Stress proteins in biology and medicine" (R. Morimoto, A. Tissières, C. Georgopoulos, eds), Cold Spring Harbor Press, pp. 287-299.

60. Hardwick, K.G. and Pelham, H.R.B. (1990) ERS1, a seven transmembrane domain protein from yeast. Nucl. Acids Res. 18, 2177.

61. Semenza, J.C., Hardwick, K.G., Dean, N. and Pelham, H.R.B. (1990) ERD2, a gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway. Cell 61, 1349-1357.

62. Lewis, M.J., Sweet, D.J. and Pelham, H.R.B. (1990) The ERD2 gene determines the specificity of the luminal ER protein retention system. Cell 61, 1359-1363.

63. Dean, N. and Pelham, H.R.B. (1990) Recycling of proteins from the Golgi compartment to the ER in yeast. J. Cell Biol. 111, 369-377.

64. Lewis, M.J. and Pelham, H.R.B. (1990) A human homologue of the yeast HDEL receptor. Nature 348, 162-163.

65. Lewis, M.J. and Pelham, H.R.B. (1990) Sequence of the BiP gene from Kluyveromyces lactis. Nucl. Acids Res. 18, 6438.

66. Pelham, H.R.B. (1990) The retention signal for luminal ER proteins. Trends Biochem. Sci. 15, 483-486.

67. Jakobsen, B.K. and Pelham, H.R.B. (1991) A conserved heptapeptide restrains the activity of the yeast heat shock transcription factor. EMBO J., 10, 369-375.

68. Semenza, J.C. and Pelham, H.R.B. (1991) A yeast homologue of a proteasome subunit. DNA Seq. 1, 219.

69. Pelham, H.R.B. (1991) Recycling of proteins between the endoplasmic reticulum and Golgi complex. Curr. Opin. Cell Biol. 3, 585-591.

70. Pelham, H.R.B. (1991) Multiple targets for Brefeldin A. Cell 67, 449-451.

71. Pelham, H.R.B. (1991) The secretion of proteins from cells. Les Cahiers de la Fondation Louis Jeantet 6, 47-56.

72. Lewis, M.J. and Pelham, H.R.B. (1992) Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the ER. Cell 68, 353-364.

73. Sweet, D.J. and Pelham, H.R.B. (1992) The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system. EMBO J. 11, 423-432.

74. Semenza, J. and Pelham, H.R.B. (1992) Changing the specificity of the sorting receptor for luminal endoplasmic reticulum proteins. J. Mol. Biol. 224, 1-5.

75. Napier, R.M., Fowke, L.C., Hawes, C., Lewis, M. and Pelham, H.R.B. (1992) Immunological evidence that plants use both HDEL and KDEL for targeting proteins to the endoplasmic reticulum. J. Cell Sci.102, 261-271.

76. Lewis, M.J. and Pelham, H.R.B. (1992) Sequence of a second human KDEL receptor. J. Mol. Biol. 226, 913-916.

77. Pelham, H.R.B., Roberts, L.M. and Lord, J.M. (1992) Toxin entry: how reversible is the secretory pathway? Trends. Cell Biol. 2, 183-185.

78. Pelham, H.R.B. (1992) The 1992 Florey lecture: The secretion of proteins from cells. Proc. Roy. Soc. B. 250, 1-10.

79. Hardwick, K.G., Boothroyd, J.C., Rudner, A.D. and Pelham, H.R.B. (1992) Genes that allow yeast cells to grow in the absence of the HDEL receptor. EMBO J. 11, 4187-4195.

80. Hardwick, K.G. and Pelham, H.R.B. (1992) SED5 encodes a 39kD integral membrane protein required for vesicular transport between the ER and the Golgi complex. J. Cell Biol. 119, 513-521.

81. Wilson, D.W., Lewis, M.J. and Pelham, H.R.B. (1993) pH-dependent binding of KDEL to its receptor in vitro. J. Biol. Chem. 268, 7465-7468.

82. Sweet, D.J. and Pelham, H.R.B. (1993) The TIP1 gene of Saccharomyces cerevisiae encodes an 80kDa cytoplasmic protein that interacts with the cytoplasmic domain of Sec20p. EMBO J. 12, 2831-2840.

83. Townsley, F.M., Wilson, D.W. and Pelham, H.R.B. (1993) Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport. EMBO J. 12, 2821-2829.

84. Pelham, H.R.B. (1993) Is epimorphin involved in vesicular transport? Cell 73, 425-426.

85. Frigerio, G. and Pelham, H.R.B. (1993) A Saccharomyces cerevisiae cyclophilin resident in the endoplasmic reticulum. J. Mol. Biol. 233, 183-188.

86. Pelham, H.R.B. (1993) Neurotransmission and secretion. Nature 364, 582.

87. Pelham, H.R.B. and Munro, S. (1993) Sorting of membrane proteins in the secretory pathway. Cell 75, 603-605.

88. Hardwick, K.G. and Pelham, H.R.B. (1994) SED6 is identical to ERG6 and encodes a putative methyltransferase required for ergosterol synthesis. Yeast 10, 265-269.

89. Townsley, F.M. and Pelham, H.R.B. (1994) The KKXX signal mediates retrieval of membrane proteins from the Golgi to the ER in yeast. Eur. J. Cell Biol. 64, 211-216.

90. Banfield, D.K., Lewis, M.J., Rabouille, C., Warren, G. and Pelham, H.R.B. (1994) Localization of Sed5, a putative vesicle targeting molecule, to the cis-Golgi network involves both its transmembrane and cytoplasmic domains. J. Cell Biol. 127, 357-371.

91. Townsley, F.M., Frigerio, G. and Pelham, H.R.B. (1994) Retrieval of HDEL proteins is required for growth of yeast cells. J. Cell Biol. 127, 21-28.

92. Pelham, H.R.B. (1994) About turn for the COPs? Cell 79, 1125-1127.

93. Pelham, H.R.B. (1994) ERD2, SED4, SED5, SEC20. In "Guidebook to the secretory pathway", J. Rothblatt, P. Novick, T. Stevens (eds), Oxford University Press, 135-138.

94. Banfield, D.K., Lewis, M.J. and Pelham, H.R.B. (1995) A SNARE-like protein required for traffic through the Golgi complex. Nature 375, 806-809.

95. Pelham, H.R.B. (1995) Sorting and retrieval between the endoplasmic reticulum and Golgi apparatus. Curr. Op. Cell Biol. 7, 530-535.

96. Pelham, H.R.B., Banfield, D.K. and Lewis, M.J. (1995) SNAREs involved in traffic through the Golgi complex. Cold Spring Harbor Symp. Quant. Biol. LX, 105-111.

97. Pelham, H.R.B. (1996) The dynamic organisation of the secretory pathway. Cell Struct. Funct. 21, 413-419.

98. Lewis, M.J. and Pelham, H.R.B. (1996) SNARE-mediated retrograde transport from the Golgi complex to the ER. Cell 85, 205-215.

99. Scheel, A.A. and Pelham, H.R.B. (1996) Purification and characterisation of the human KDEL receptor. Biochemistry 35, 10203-10209.

100. Rayner, J. and Pelham, H.R.B. (1997) Transmembrane domain dependent sorting of proteins to the ER and plasma membrane in yeast. EMBO J. 16, 1832-1841.

101. Nichols, B.J., Ungermann, C., Pelham, H.R.B., Wickner, W.T. and Haas, A. (1997) Homotypic vacuolar fusion mediated by t- and v-SNAREs. Nature 387, 199-202.

102. Lewis, M.J., Rayner, J. and Pelham, H.R.B. (1997) A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum. EMBO J. 16, 3017-3024.

103. Pelham, H.R.B. (1997) Green light for Golgi traffic. Nature 389, 17-19.

104. Pelham, H.R.B. (1997) SNAREs and the organisation of the secretory pathway. Eur. J. Cell Biol. 74, 311-314.

105. Holthuis, J.C.M., Nichols, B.J., Dhruvakumar, S. and Pelham, H.R.B. (1998) Two syntaxin homologues in the TGN/endosomal system of yeast. EMBO J. 17, 113-126.

106. Pelham, H.R.B. (1998) Getting through the Golgi complex. Trends Cell Biol. 8, 45-49.

107. Scheel, A.A. and Pelham, H.R.B. (1998) Identification of amino acids in the binding pocket of the human KDEL receptor. J. Biol. Chem. 273, 2467-2472.

108. Ungermann, C., Nichols, B.J., Pelham, H.R.B. and Wickner, W. (1998) A vacuolar v-t-SNARE complex, the predominant form in vivo and on isolated vacuoles, is disassembled and activated for docking and fusion. J. Cell Biol. 140, 61-69.

109. Nichols, B.J. and Pelham, H.R.B. (1998) SNAREs and membrane fusion in the Golgi Apparatus. Biochim. Biophys. Acta, 1404, 9-31.

110. Wooding, S. and Pelham, H.R.B. (1998) The dynamics of Golgi protein traffic visualised in living yeast cells. Mol. Biol. Cell 9, 2667-2680.

111. Nichols, B.J., Holthuis, J.C.M. and Pelham, H.R.B. (1998) The Sec1p homologue Vps45p binds to the syntaxin Tlg2p. Eur. J. Cell Biol. 77, 263-268.

112. Holthuis, J.C.M., Nichols, B.J. and Pelham, H.R.B. (1998) The syntaxin Tlg1p mediates trafficking of chitin synthase 3 to polarized growth sites in yeast. Mol. Biol. Cell 9, 3383-3397.

113. Pelham, H.R.B. (1999) SNAREs and the secretory pathway - lessons from yeast. Exp. Cell Res. 247, 1-8.

114. Pelham, H.R.B. (1999) Croonian lecture - Intracellular membrane traffic: getting proteins sorted. Phil. Trans. Roy. Soc. B. 354, 1-9.

115. Conchon, S., Cao, X., Barlowe, C. and Pelham, H.R.B. (1999) Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex. EMBO J. 18, 3934-3946.

116. Pelham, H.R.B. (2000) Using sorting signals to retain proteins in the Endoplasmic Reticulum. Meth. Enzymol. 327, 279-283.

117. Lewis, M.J., Nichols, B.J., Prescianotto-Baschong, C., Riezman, H. and Pelham, H.R.B. (2000) Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes. Mol. Biol. Cell 11, 23-38.

118. Pelham, H.R.B. (2000) Getting stuck in the Golgi. Traffic 1, 191-192.

119. Siniossoglou, S., Hurt E.C. and Pelham, H.R.B. (2000) Psr1p/Psr2p, two plasma membrane phosphatases with an essential DXDX(T/V) motif required for sodium stress response in yeast. J. Biol. Chem. 275, 19352-19360.

120. Reggiori, F., Black, M.W. and Pelham, H.R.B. (2000) Polar transmembrane domains target proteins to the interior of the yeast vacuole. Mol. Biol. Cell 11, 3737-3749.

121. Siniossoglou, S., Peak-Chew, S.Y. and Pelham, H.R.B. (2000) Ric1p and Rgp1p form a Complex that Catalyses Nucleotide Exchange on Ypt6p. EMBO J. 19, 4885-4894.

122. Black, M.W. and Pelham, H.R.B. (2000) A selective transport route from Golgi to late endosomes that requires the GGA proteins. J. Cell Biol. 151, 587-600.

123. Pelham, H.R.B. and Rothman, J.E. (2000) The debate about transport in the Golgi - two sides of the same coin? Cell 102, 713-719.

124. Pelham, H.R.B. (2001) The discovery of the KDEL signal. In "100 great experiments" at

125. Pelham, H.R.B. (2001) SNAREs and the specificity of membrane fusion. Trends Cell Biol. 11, 99-101.

126. Black, M.W. and Pelham, H.R.B. (2001) Membrane traffic: how do GGAs fit in with the adaptors? Curr. Biol. R460-R462.

127. Reggiori, F. and Pelham, H.R.B. (2001) Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting. EMBO J. 20, 5176-5186.

128. Siniossoglou, S. and Pelham, H.R.B. (2001) An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes. EMBO J. 20,5991-5998.

129. Pelham, H.R.B. (2001) A trendsetting decade for cell biology. Trends Cell Biol. 11, 459.

130. Pelham, H.R.B. (2001) Traffic through the Golgi apparatus. J. Cell Biol. 155, 1099-1101.

131. Reggiori, F. and Pelham, H.R.B. (2002) A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies. Nat. Cell Biol. 4, 117-123.

132. Pelham, H.R.B. (2002) Insights from yeast endosomes. Curr. Op. Cell Biol. 14. 454–462.

133. Siniossoglou, S. and Pelham, H.R.B. (2002) Vps51p links the VFT complex to the SNARE Tlg1p. J. Biol Chem. 277, 48318-48324.

134. Lewis, M.J. and Pelham, H.R.B. (2002) A new yeast endosomal SNARE related to mammalian syntaxin 8. Traffic 3, 922-929.

135. Hettema, E.H., Lewis, M.J., Black, M.W. and Pelham, H.R.B. (2003) Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes. EMBO J. 22, 548-557.

136. Valdez-Taubas, J. and Pelham, H.R.B. (2003) Slow diffusion of proteins in the yeast plasma membrane allows polarity to be maintained by endocytic cycling. Curr. Biol. 13, 1636–1640.

137. Hettema, E.H, Valdez-Taubas, J. and Pelham, H.R.B. (2004) Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins. EMBO J. 23, 1279-1288.

138. Fridmann-Sirkis, Y., Siniossoglou, S. and Pelham, H.R.B. (2004) TMF is a Golgin that binds Rab6 and influences Golgi morphology. BMC Cell Biol. 5, 18.

139. Pelham, H.R.B. (2004) Membrane traffic: GGAs sort ubiquitin. Curr. Biol. 14, R357-R359.

140. Valdez-Taubas, J. and Pelham, H.R.B. (2005) Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation. EMBO J. 24, 2524-2532.

141. Fridmann-Sirkis, Y., Kent, H.M., Lewis, M.J., Evans, P.R. and Pelham, H.R.B. (2006) Structural analysis of the interaction between the SNARE Tlg1 and Vps51. Traffic 7, 182-190.

142. Stimpson, H.E.M., Lewis, M.J. and Pelham, H.R.B. (2006) Transferrin receptor-like proteins control the degradation of a yeast metal transporter. EMBO J. 25, 662-672.

143. Pelham, H.R.B. (2006) Maturation of Golgi cisternae directly observed. Trends Biochem. Sci. 31, 601-604.

144. Sullivan, J.A., Lewis, M.J., Nikko, E. and Pelham, H.R.B. (2007) Multiple interactions drive adaptor-mediated recruitment of the ubiquitin ligase Rsp5 to membrane proteins in vivo and in vitro. Mol. Biol. Cell 18, 2429-2440.

145. Nikko, E., Sullivan, J.A. and Pelham, H.R.B (2008) Arrestin-like proteins mediate ubiquitination and endocytosis of the yeast metal transporter Smf1. EMBO Rep. 9, 1216-1221.

146. Mund, T. and Pelham, H.R.B. (2009) Control of the activity of WW-HECT domain E3 ubiquitin ligases by Ndfip proteins. EMBO Rep. 10, 501-507.

147. Lewis, M.J. and Pelham, H.R.B. (2009) Inefficient quality control of thermosensitive proteins on the plasma membrane. PLoS ONE 4: e5038. doi:10.1371/journal.pone.0005038.

148. Nikko, E. and Pelham, H.R.B. (2009) Arrestin-mediated endocytosis of yeast plasma membrane transporters. Traffic 10, 1856-1867.

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