Franz Oesch - Curriculum Vitae#


Institute of Toxicology, University of Mainz, Obere Zahlbacher Str. 67, D-55131 Mainz, Germany
Born November 14, 1938 in Zurich, Switzerland


Education and Qualifications:
  • 1961-1969 University of Fribourg, Switzerland: Study of Chemistry and Biology
  • 1965 Lizentiat in Chemistry and Biology, University of Fribourg, Switzerland
  • 1969 Ph.D. (Dr. rer. nat.), University of Fribourg, Switzerland
  • 1973 Privatdozent for Pharmacology and Toxicology, University of Basel, Switzerland

Postgraduate Training and Post Held:
  • 1965-1969 Junior (65-66), then Senior (66*69) Assistant at the University of Fribourg, Switzerland
  • 1969-1971 Fellow of the Visiting Program of the US Health Service, NIAMD, National Institutes of Health, Bethesda, MD, USA
  • 1972-1974 Wissenschaftlicher Adjunkt (Senior Research Associate), Department of Pharmacology, Biozentrum of the University of Basel, Switzerland
  • 1974-1981 Professor (C3) of Pharmacology and Toxicology; Head, Section on Molecular Pharmacology, University of Mainz, Germany
  • 1981-1983 Professor (C4) of Pharmacology and Toxicology; Chairman, Department of Molecular Pharmacology, University of Mainz
  • 1983 on Professor (C4) of Pharmacology and Toxicology
  • 1983-2004 Director, Institute of Toxicology, University of Mainz
April 2004 on In “active” retirement (still project leader of some grant projects)
Main Professional and Research Interests:

Genotoxicity; Chemical carcinogenesis; Metabolism of drugs and other foreign compounds; Enzymatic control of reactive metabolites; Proliferation control

Membership of the Editorial Advisory Boards of Scientific Journals:
(Present and past)

  • Archives Internationales de Pharmacodynamie et de Thérapie
  • Archives of Toxicology
  • Biochemical Pharmacology
  • Carcinogenesis
  • Chemico-Biological Interactions
  • Comprehensive Toxicology
  • Drug Metabolism and Disposition
  • Drug Metabolism Reviews
  • European Journal of Cancer
  • Experientia
  • Journal of Biochemical Toxicology
  • Mutation Research
  • Naunyn-Schmiedeberg´s Archives of Pharmacology (Editor)
  • Pharmacology and Toxicology
  • Xenobiotica

Membership in Executive Committees of Scientific Societies:
(Present and Past)

  • German Society of Pharmacology, Section on Toxicology (Chairman)
  • German Cancer Society, Section of Experimental Cancer Research (Chairman)
  • International Society for the Study of Xenobiotics (ISSX) (President)
  • International Union of Pharmacology (IUPHAR), Section on Toxicology (Chairman)
  • International Union of Pharmacology (IUPHAR), Section on Drug Metabolism (Councillor)
  • International Union of Toxicology (IUTOX) (Councillor)

Honorary Memberships in Scientific Societies:
  • International Society for the Study of Xenobiotics (ISSX)
  • German Society of Toxicology

Membership of Permanent Advisory commissions:
(Present and Past)

  • Committee of the German Society of Pharmacology for conferring the title "Toxicologist DGPT"
  • Advisory board of the priority research program of the German Research Council "Mechanisms of the Toxic Effects of Drugs and Exogenous Substances"
  • Advisory committee of the special research area "Experimental and Clinical Tumor Research", Essen, Germany
  • Advisory committee of the special research area "Cancer Research", Heidelberg, Germany
  • Advisory committee of the special research area "Toxic materials from incomplete combustion", Darmstadt, Germany
  • Advisory committee of the special research area "Molecular mechanisms of carcinogenic primary events", Würzburg
  • Advisory committee of the special research area "Molecular and cellular mediators of the toxicity of exogenous chemical compounds", Düsseldorf, Germany
  • Scientific Advisory Board of the Swiss Institute for Experimental Cancer Research, Epalinges s./Lausanne
  • Expert committee on toxic substances, Swiss Health Ministry, Bern
  • Expert of the European Commission Science, Research, Development
  • Senate Commission for Cancer Research of the German Research Council
  • Steering Committee for the German*American Cooperation in Cancer Research
  • Steering Committee for the German*Japan Cooperation in Cancer Research
  • Scientific Advisory Board of the CEIMED (Centre d´Études des Interférences des Médicaments et autres Xénobiotiques sur les Membranes et les Systèmes Biologiques), Nancy, France
  • Toxicology Steering Committee of the European Science Foundation
  • Expert committee "Alternatives to experimentations with animals" of the Swiss National Science Foundation, Bern
  • "Expert Pharmacologue Toxicologue Specialisé en Cancérogénèse et Mutagénèse" of the Ministère de la Santé of France
  • Scientific Advisory Board of the Central Institute of Occupational Medicine, Hamburg, Germany
  • Environmental Toxicology Board of the State Rheinland*Pfalz, Germany
  • Executive body of the Humboldt Foundation for conferring Humboldt Fellowships and Humboldt Prizes
  • Expert for toxicology of the "Wissenschaftsrat" (Advisory body of the German Federal Government for research and development)
  • AEGL committee of the National Academy of Sciences USA
  • Expert committee to develop IARC Monograph on ‘Cadmium, Nickel, Some Epoxides, Miscellaneous Industrial Chemicals and General Considerations on Volatile Anaesthetics
  • Expert committee to develop IARC Monograph on ‘1,3*Butadiene, Ethylene Oxide and Vinyl Halides (Vinyl Fluoride, Vinyl Chloride and Vinyl Bromide)’
  • Expert committee to develop IARC Monograph on ‘Some Industrial and Cosmetic Dyes, and Related Exposures’
  • EU ECVAM Expert Committee on the development of a quality assessment tool for toxicological data

Prizes
  • Professor Max Cloetta Prize 1977
  • Robert Koch Prize 1982
  • GUM Prize 1985
  • Prize of the Rheinisch*Westfälische Academy of Sciences 1989
  • German Cancer Prize 1990
  • Prize for Scientific Innovation of the State Rheinland*Pfalz 1999

Other Honours:
  • Most Quoted Scientists: belonging to the top 0.1 % (Current Contents No. 41, October 12, 1981)
  • Walter Straub Memorial Lecture, Munich 1983
  • The Biochemical Society 75th Anniversary Symposium Honoured Lecture, London, 1986
  • Keynote Lecture, International ISSX Meeting, Amsterdam, 1991
  • Otto Warburg Memorial Lecture, Berlin, 1992
  • Election to the Academia Europea, 1992
  • International Society for the Study of Xenobiotics Award, 1993
  • Novum Lecture, Karolinska Institute, Novum*Stockholm, 1994
  • MDC-Lecture, Max Delbrück Centrum für Molekulare Medizin, Berlin, 1995
  • International Union Against Cancer Roll of Honour, 1996
  • IEM Lecture, Karolinska Institute, Stockholm, 1997
  • Keynote Review, International EAPCCT Congress, Zürich, 1998
  • Keynote Lecture, European Workshop on Drug Metabolism, Kopenhagen, 1998
  • Election to the National Academy of Sciences of Germany 1999
  • Gerhard Zbinden Memorial Lecture Award, 2000
  • Werner Heisenberg*Medaille, 2000
  • Salk Lecture, Salk Institute, La Jolla, 2002
  • Election to the National Academy of Medicine of France, 2008
  • More than 700 publications, many in top journals (Science, Nature, PNAS, J Cell Biol,EMBO J, FASEB J, Cancer Res, Oncogene, …)
  • More than 500 invited lectures
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