Jean-Louis Mergny#


Jean-Louis Mergny
Email:jean-louis.mergny 'at' inserm.fr
Membership Number:4900
Membership type:ORDINARY
Main Country of Residence:FRANCE
Section:BIOCHEMISTRY & MOLECULAR BIOLOGY
Username:jmergny
Elected:2019
ORCID:0000-0003-3043-8401
Homepage: http://www.iecb.u-bordeaux.fr/index.php/fr/equipes/unusual-nucleic-acid-structures


Present and Previous Positions
  • 2019 Group Leader at Institut Curie
  • 2015 - 2018 Director of IECB www.iecb.u-bordeaux.fr and its service unit / tech. platforms
  • 2011 - 2018 Director of ARNA laboratory (INSERM – CNRS – U. Bordeaux)
  • 2016 - 2017 Deputy Director of SIRIC BRIO (Bordeaux Cancer initiative).
  • 2006 - 2009 Deputy Director, Museum Nat. Hist. Naturelle, Paris (Dir. C. Giovannangeli)
  • 1993 - 2006 INSERM Researcher (CR2 – CR1 – DR2) INSERM U565, Paris (Dir. C. Hélène)
  • 1992 - 1993 Post-doctoral fellow, Basel, CH (Pr. Walter Gehring) Antisense oligos in Drosophila
  • 1989 - 1991 PhD in Pharmacology, Paris (Pr. C. Hélène) Triple-helices: spectroscopic studies

Fields of Scholarship
  • Nucleic acids structure
  • Drug-DNA interactions
  • G-quadruplexes
  • Applications of unusual DNA/RNA structures for nano- and bio-technologies
  • Biophysical / Physico-chemical studies (Absorbance, Circular dichroism, Fluorescence / FRET)
  • Genome analysis: development of predictive tools
  • Antiviral / Antitumoral effects of nucleic acid ligands

Honours and Awards
  • 2019+ Senior Chair from Institut Curie, France
  • 2018+ Foreign Expert. State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, P.R. China
  • 2016 - 2021 Key foreign scientist, Symbit project. Institute of Biophysics, Czech Academy of Sciences, Brno, Czech Republic
  • 2017 Mitacs Award for Outstanding Innovation awarded for a student working with us
  • 2012 Best thesis (SVS doctoral school): P.L.T. Tran
  • 2010 Guest Professor, Chinese Academy of Sciences, (Changchun, China)
  • 2009 "Chaire d'Accueil" in Bordeaux. Aquitaine Regional Council
  • 2002 "Therapeutical research" INSERM Award, 2002
  • 2001 "Maurice Nicloux" SFBBM (2001)
  • 2000 "Labbey" Award from the French Academy of Sciences
  • 1992 "Nine Choucroun" price for thesis

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