Paul Matthews - Selected Publications#

Over 330 peer reviewed publications, as well as many invited reviews, chapters and co-authored books (including The Bard on the Brain, 2004 IPPY Award Winner for Best Books of the Year (Psychology Category)). Over 44200 citations (4 Jan 2015) with over 24800 since 2010; Google Scholar h-index 107. Selected publications from the last 5 years include:

1. Douaud G, Groves AR, Tamnes CK, Westlye LT, Duff EP, Engvig A, Walhovd KB, James A, Gass A, Monsch AU, Matthews PM, Fjell AM, Smith SM, Johansen-Berg H. A common brain network links development, aging, and vulnerability to disease. Proc Natl Acad Sci U S A. 111(49): 17648-53. (Too recent for citations, but received extensive press coverage by international news media on publication and continues to attract strong interest).

2. Owen DR, Gunn RN, Rabiner EA, Bennacef I, Fujita M, Kreisl WC, Innis RB, Pike VW, Reynolds R, Matthews PM, Parker CA. 2011. Mixed-affinity binding in humans with 18-kDa translocator protein ligands. J Nucl Med. 52(1):24-32 (95 citations; discovery of major functional differences in the target protein in human population)

3. Owen DR, Yeo AJ, Gunn RN, Song K, Wadsworth G, Lewis A, Rhodes C, Pulford DJ, Bennacef I, Parker CA, Stjean PL, Cardon LR, Mooser VE, Matthews PM, Rabiner EA, Rubio JP. 2012. An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28. J Cereb Blood Flow Metab. 32(1):1-5 (84 citations and now used as standard genetic screening test)

4. De Silva A, Salem V, Long CJ, Makwana A, Newbould RD, Rabiner EA, Ghatei MA, Bloom SR, Matthews PM, Beaver JD, Dhillo WS. 2011. The gut hormones PYY3-36 and GLP-17-36 amide reduce food intake and modulate brain activity in appetite centres in humans. Cell Metab. 14(5):700-6 (68 citations and results used by major pharma company to design development strategy)

5. Baranzini SE, Srinivasan R, Khankhanian P, Okuda DT, Nelson SJ, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D. 2010. Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. Brain. 133(9):2603-11 (47 citations and still one of the few examples of using imaging genetics for mechanistic validation)

6. Filippini N, Macintosh BJ, Hough MG, Goodwin GM, Frisoni GB, Smith SM, Matthews PM, Beckmann CF, Mackay CE. 2009. Distinct patterns of brain activity in young carriers of the APOE 4 allele. Proc Natl Acad Sci U S A. 106(17):7209-14 (541 citations and provides some of the first evidence for abnormalities of small vessel regulation in Alzheimer’s)

7. Johansen-Berg H, Gutman DA, Behrens TE, Matthews PM, Rushworth MF, Katz E, Lozano AM, Mayberg HS. 2008. Anatomical Connectivity of the Subgenual Cingulate Region Targeted with Deep Brain Stimulation for Treatment-Resistant Depression. Cereb Cortex. 18(6):1374-83 (270 citations and remains a unique contribution to the rationale for deep brain stimulation targeting in depression)

8. Douaud G, Menke RA, Gass A, Monsch AU, Rao A, Whitcher B, Zamboni G, Matthews PM, Sollberger M, Smith S. 2013. Brain microstructure reveals early abnormalities more than two years prior to clinical progression from mild cognitive impairment to Alzheimer’s disease. J Neurosci. 33(5):2147-55 (151 citations and provides novel improvement in sensitivity of MRI to early changes with dementia)

9. Stagg CJ, Wylezinska M, Matthews PM, Johansen-Berg H, Jezzard P, Rothwell JC, Bestmann S. 2009. The Neurochemical Effects of Theta burst Stimulation as assessed by Magnetic Resonance Spectroscopy. Neurophysiol. 101(6):2872-7 (112 citations for important study elucidating mechanism of powerful neurophysiological effects)

10. Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, Pelletier D, Wu W, Uitdehaag BM; GeneMSA Consortium, Kappos L, Polman CH, Matthews PM, Hauser SL, Gibson RA, Oksenberg JR, Barnes MR. 2009. Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet. 1(11):2078-90 (241 citations for one of the first larger, well curated genome wide association studies in multiple sclerosis, highlighting extensions to pathway analysis)
Imprint Privacy policy « This page (revision-2) was last changed on Tuesday, 24. November 2015, 12:25 by Kaiser Dana
  • operated by