Ülo Langel - Selected publications#


1: Lehto T, Kurrikoff K, Langel Ü. Cell-penetrating peptides for the delivery of nucleic acids. Expert Opin Drug Deliv. 2012 Jul;9(7):823-36. doi:10.1517/17425247.2012.689285. Epub 2012 May 17. Review. PubMed PMID: 22594635.

2: Ezzat K, Helmfors H, Tudoran O, Juks C, Lindberg S, Padari K, El-Andaloussi S, Pooga M, Langel U. Scavenger receptor-mediated uptake of cell-penetrating peptide nanocomplexes with oligonucleotides. FASEB J. 2012 Mar;26(3):1172-80. doi:10.1096/fj.11-191536. Epub 2011 Dec 1. PubMed PMID: 22138034.

3: Lehto T, Ezzat K, Langel U. Peptide nanoparticles for oligonucleotide delivery. Prog Mol Biol Transl Sci. 2011;104:397-426. doi:10.1016/B978-0-12-416020-0.00010-3. Review. PubMed PMID: 22093225.

4: Florén A, Mäger I, Langel U. Uptake kinetics of cell-penetrating peptides. Methods Mol Biol. 2011;683:117-28. doi: 10.1007/978-1-60761-919-2_9. PubMed PMID:2105312.

5: El-Andaloussi S, Järver P, Johansson HJ, Langel U. Cargo-dependent cytotoxicity and delivery efficacy of cell-penetrating peptides: a comparative study. Biochem J. 2007 Oct 15;407(2):285-92. PubMed PMID: 17627607; PubMed Central PMCID: PMC2049024.

6: Lundberg P, El-Andaloussi S, Sütlü T, Johansson H, Langel U. Delivery of short interfering RNA using endosomolytic cell-penetrating peptides. FASEB J. 2007 Sep;21(11):2664-71. Epub 2007 Apr 26. PubMed PMID: 17463227.

7: Lindgren M, Rosenthal-Aizman K, Saar K, Eiríksdóttir E, Jiang Y, Sassian M, Ostlund P, Hällbrink M, Langel U. Overcoming methotrexate resistance in breast cancer tumour cells by the use of a new cell-penetrating peptide. Biochem Pharmacol. 2006 Feb 14;71(4):416-25. Epub 2006 Jan 10. PubMed PMID: 16376307.

8: Saar K, Mazarati AM, Mahlapuu R, Hallnemo G, Soomets U, Kilk K, Hellberg S, Pooga M, Tolf BR, Shi TS, Hökfelt T, Wasterlain C, Bartfai T, Langel U. Anticonvulsant activity of a nonpeptide galanin receptor agonist. Proc Natl Acad Sci U S A. 2002 May 14;99(10):7136-41. PubMed PMID: 12011470; PubMed Central PMCID: PMC124541.

9: Pooga M, Langel U. Targeting of cancer-related proteins with PNA oligomers. Curr Cancer Drug Targets. 2001 Nov;1(3):231-9. Review. PubMed PMID: 12188881.

10: Pooga M, Soomets U, Hällbrink M, Valkna A, Saar K, Rezaei K, Kahl U, Hao JX, Xu XJ, Wiesenfeld-Hallin Z, Hökfelt T, Bartfai T, Langel U. Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nat Biotechnol. 1998 Sep;16(9):857-61. PubMed PMID: 9743120.
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