Eduard Hurt - List of Publications#


1. A. Futami, E. C. Hurt and G. Hauska: Vectorial redox reactions of physiological chinones: requirement of a minimum length of the isoprenoid side chain. Biochim. Biophys. Acta 547, 583-596 (1979).


2. A. Baccarini-Melandri, N. Gabellini, B.A. Melandri, E. C. Hurt and G. Hauska: Structural requirements of quinone co-enzymes for endogenous and dye-mediated coupled electron transport in photosynthesis. J. Bioenerg. Biomembr. 12, 95-110 (1980).


3. E. C. Hurt and G. Hauska: A cytochrome f/b6 complex of five polypeptides with plastoquinol/plastocyanin oxidoreductase activity from spinach chloroplasts. Eur. J. Biochem. 117, 591-599 (1981).

4. E. C. Hurt, G. Hauska and R. Malkin: Isolation of the Rieske FeS protein from the isolated cytochrome b6f complex from spinach chloroplasts. FEBS Lett. 134, 1-5 (1981).


5. E. C. Hurt, and G. Hauska: Oxidant-induced reduction of cytochrome b6 in the isolated cytochrome b6f complex from chloroplasts. Photobiochem. Photobiophys. 4, 9-15 (1982).

6. W. Oettmeier, K. Masson, H. Soll, E. C. Hurt and G. Hauska: Photoaffinity labelling of plastoquinone binding sites in the chloroplast cytochrome b6f complex. FEBS Lett. 144, 313-317 (1982).

7. R. Prince, K. Matsuura, E. C. Hurt, G. Hauska and L. Dutton: Reduction of cytochrome b6 and cytochrome f in isolated plastoquinol/plastocyanin oxidoreductase driven by photochemical reaction centers from Rhodopseudomonas sphaeroides. J. Biol. Chem. 257, 3379-3381 (1982).

8. N. Gabellini, J. Bowyer, E. C. Hurt, B. Melandri and G. Hauska: A cytochrome bc1 complex with ubiquinol/cytochrome c2 oxidoreductase activity from Rhodopseudomonas sphaeroides. Eur. J. Biochem. 126, 105-111 (1982).

9. M. Krinner, G. Hauska, E. C. Hurt and W. Lockau: A cytochrome b6f complex with plastoquinol/plastocyanin reductase activity from Anabaena variabilis. Biochim. Biophys. Acta 681, 110-117 (1982).

10. A. Baccarini-Melandri, N. Gabellini, B. Melandri, K. Jones, A. Rutherford, A. Crofts and E. C. Hurt: Differential extraction and structural specificity of specialized ubiquinone molecules in secondary electron transfer in chromatophors from R. sphaeroides. Arch. Biochem. Biophys. 216, 566-580 (1982).

11. G. Hauska, N. Gabellini, E. C. Hurt, M. Krinner and W. Lockau: Cytochrome b/c complexes with polyprenyl quinol:cytochrome c oxidoreductase activity from A. variabilis and R. sphaeroides: comparison of preparations from chloroplasts and mitochondria. Biochem. Soc. Trans. 10, 340-341 (1982).

12. E. C. Hurt, G. Hauska and Y. Shahak: Electrogenic proton translocation by the chloroplast cytochrome b6complex reconstituted into phospholipid vesicles. FEBS Lett. 149, 211-216 (1982).

13. G. Hauska and E. C. Hurt: Pool function behavior and mobility of isoprenoid quinones. Quinones in Energy Conserving Membranes (ed. B.L. Trumpower), 87-110 (1982).

14. E. C. Hurt and G. Hauska: Identification of the polypeptides in the cytochrome b6f complex from spinach chloroplasts with redox-center carrying subunits. J. Bioenerg. Biomembr. 14, 405-424 (1982).

15. E. C. Hurt and G. Hauska: Involvement of a plastoquinone bound within the isolated cytochrome b6f complex from chloroplasts in the oxidant-induced reduction of cytochrome b6. Biochim. Biophys. Acta 682, 466-473 (1982).


16. E. C. Hurt, N. Gabellini, Y. Shahak, W. Lockau and G. Hauska: Extra proton translocation and membrane potential generation - Universal properties of cytochrome bc1/b6f complexes. Arch. Biochem. Biophys. 225, 879-885 (1983).

17. E. C. Hurt and G. Hauska: Cytochrome b6 from isolated cytochrome b6f complexes - Evidence for two spectral forms with different midpoint potentials. FEBS Lett. 153, 413-419 (1983).

18. G. Hauska, E. C. Hurt, N. Gabellini and W. Lockau: Comparitive aspects of quinol/cytochrome c/plastocyanin oxidoreductases. Biochim. Biophys. Acta 726, 97-133 (1983).

19. R.G. Herrmann, P. Westhoff, J. Alt, P. Winter, J. Tittgen, C. Bisanz, B.B. Sears, N. Nelson, E. C. Hurt, G. Hauska, A. Viebrock and W. Sebald: Identification and characterization of genes for polypeptides of the thylakoid membrane. Structure and Function of Plant Genomes (eds. O. Cifferri and L. Dure), 143-153, Plenum Publishing Corporation (1983).

20. J. Alt, P. Westhoff, B. Sears, N. Nelson, E. C. Hurt, G. Hauska and R. Herrmann: Genes and transcripts for the polypeptides of the cytochrome b6f complex from spinach thylakoid membranes. EMBO J. 2, 979-986 (1983).


21. E. C. Hurt and G. Hauska: Purification of membrane-bound cytochromes and a photoreactive P840 protein complex of the green sulfur bacterium Chlorobium limicola f. thiosulfatophilum. FEBS Lett. 168, 149-154 (1984).

22. E. C. Hurt, B. Pesold-Hurt and G. Schatz: The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix. EMBO J. 3, 3149-3156 (1984).

23. E. C. Hurt, B. Pesold-Hurt and G. Schatz: The cleavable prepiece of an imported mitochondrial protein is sufficient to direct cytosolic dihydrofolate reductase into the mitochondrial matrix. FEBS Lett. 178, 306-310 (1984).


24. E. C. Hurt, B. Pesold-Hurt, K. Suda, W. Oppliger and G. Schatz: The first twelve amino acids (less than half of the presequence) of an imported mitochondrial protein can direct mouse cytosolic dihydrofolate reductase into yeast mitochondrial matrix. EMBO J. 4, 2061-2068 (1985).

25. E. C. Hurt and B. Pesold-Hurt: The cleavable prepiece of cytochrome c oxidase subunit IV carries all the information for importing an attached cytosolic protein into the yeast mitochondrial matrix. Current Communications in Molecular Biology: Protein transport and secretion (ed. M.-J. Gething), 200-205, Cold Spring Harbor Laboratory (1985).

26. E. C. Hurt, U. Müller and G. Schatz: The first twelve amino acids of a yeast outer membrane protein can direct a nuclear-encoded cytochrome oxidase subunit to the mitochondrial inner membrane. EMBO J. 4, 3509-3518 (1985).


27. A. van Loon and E. C. Hurt: Intracellular targeting and intra-mitochondrial sorting of imported mitochondrial proteins. in Biological Research on Industrial Yeasts (eds. T.G. Stewart, Russell, R.D. Klein, and R.R. Hiebsch, eds.) Uniscience Series, Volume 2 (Fundamental aspects), CRC Press (1986).

28. E. C. Hurt and A. van Loon: How proteins find mitochondria and intra-mitochondrial compartments. Trends Biol. Sci. 11, 204-207 (1986).

29. E. C. Hurt, N. Soltanifar, M. Goldschmidt-Clermont, J.-D. Rochaix and G. Schatz: The cleavable presquence of an imported chloroplast protein directs attached polypeptides into yeast mitochondria. EMBO J. 5, 1343-1350 (1986).

30. E. C. Hurt, M. Golschmidt-Clermont, B. Pesold-Hurt, J.-D. Rochaix and G. Schatz: A mitochondrial presequence can transport a chloroplast encoded protein into yeast mitochondria. J. Biol. Chem. 261, 11440-11443 (1986).


31. E. C. Hurt, D. Allison, U. Müller and G. Schatz: Amino-terminal deletions in the presequence of an imported mitochondrial protein block the targeting function and proteolytic cleavage of the presequence at the carboxy-terminus. J. Biol. Chem. 262, 1420-1424 (1987).

32. E. C. Hurt and G. Schatz: A cytosolic protein contains a cryptic mitochondrial targeting sequence. Nature 325, 499-503 (1987).

33. E. C. Hurt: Unravelling the role of ATP in post-translational protein translocation. Trends Biol. Sci. 12, 369-370 (1987).


34. E. C. Hurt, A. McDowall and T. Schimmang: Nucleolar and nuclear envelope proteins of the yeast Saccharomyces cerevisiae. Eur. J. Cell Biol. 46, 554-563 (1988).

35. E. C. Hurt: A novel nucleoskeletal-like protein located at the nuclear periphery is absolutely required for the life cycle of Saccharomyces cerevisiae. EMBO J. 7, 4323-4333 (1988).


36. T. Schimmang and E. C. Hurt: A 40 kDa nuclear membrane protein changes its concentration and localization within the nuclear envelope of the yeast Saccharomyces cerevisiae in a cell cycle dependent manner. Eur. J. Cell Biol. 49, 33-41(1989).

37. E. C. Hurt: NSP1, a yeast protein located at the nuclear periphery is required for the cell-cycle of Saccharomyces cerevisiae. J. Cell Sci. Suppl. 12, 243-252 (1989).

38. T. Schimmang, D. Tollervey, H. Kern, R. Frank and E. C. Hurt: A yeast nucleolar protein related to human fibrillarin is associated with small nucleolar RNA and essential for viability. EMBO J. 8, 4015-4025 (1989).


39. U. Nehrbass, H. Kern, A. Mutvei, H. Horstmann, B. Marshallsay and E. C. Hurt: NSP1: a yeast nuclear envelope protein localized at the nuclear pores exerts its essential function by its carboxy-terminal domain. Cell 61, 979-989 (1990).

40. D. Tollervey and E. C. Hurt: The role of small nucleolar ribonucleoproteins in ribosome biogenesis. Mol. Biol. Report 14, 103-206 (1990).

41. E. C. Hurt: Targeting of a cytosolic protein to the nuclear periphery. J. Cell Biol. 111, 2829-2837 (1990).


42. R. P. Jansen, E. C. Hurt, H. Kern, H. Lehtonen, M. Carmo-Fonseca, B. Lapeyere and D. Tollervey: Evolutionary conservation of the human protein fibrillarin and its functional expression in yeast. J. Cell Biol. 113, 715-727 (1991).

43. D. Tollervey, H. Lehtonen, M.Carmo-Fonseca and E. C. Hurt: The small nucleolar RNP protein NOP1 (fibrillarin) is required for pre-rRNA processing in yeast. EMBO J. 10, 573-583 (1991).

44. M. Carmo-Fonseca, D. Tollervey, R. Pepperkok, S.M.L. Barabino, A. Merdes, C. Brunner, P.D. Zamore, M.R. Green, E.C. Hurt and A.I. Lamond: Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery. EMBO J. 10, 195-206 (1991).

45. M. Carmo-Fonseca, H. Kern and E.C. Hurt: Human nucleoporin p62 and the essential yeast nuclear pore protein NSP1 show sequence homology and a similar domain organization. Eur. J. Cell Biol. 55, 17-30 (1991).

46. E.C. Hurt und M. Carmo-Fonseca: Across the nuclear pores with the help of nucleoporins. Cromosoma 101, 199-205 (1991).


47. E.C. Hurt, A. Mutvei und M. Carmo-Fonseca: The nuclear envelope of the yeast Saccharomyces cerevisiae. Int. Rev. Cytol. 136, 145-184 (1992).

48. U. Nehrbass and E. C. Hurt: Nuclear transport and nuclear pores in yeast. Int. J. Gen. Mol. Microbiol. 62, 3-14 (1992). 49. A. Mutvei, S. Dihlmann, W. Herth and E.C. Hurt: Depletion of the nucleoporin NSP1 in yeast inhibits nuclear pore formation and nuclear transport of a nuclear reporter protein. Eur. J. Biol. 59, 280-295 (1992).

50. Christian Wimmer, Valérie Doye, Paola Grandi, Ulf Nehrbass and Eduard C. Hurt: A New Subclass of Nucleoporins that Functionally Interacts with Nuclear Pore Protein NSP1 EMBO J. 11, 5051-5061 (1992).


51. C. Wimmer, V. Doye, U. Nehrbass, N. Schlaich and E.C. Hurt: Approaches towards a genetic analysis of the nuclear pore complex in yeast. In 'Protein Synthesis and Targeting' (eds. A.J.P. Brown, M.F. Tuite and J.E.G. McCarthy) NATO ASI Series, Vol. H 71, pp. 269-281, Springer-Verlag, Berlin-Heidelberg (1993).

52. D. Tollervey, H. Lehtonen, R. Jansen, H. Kern and E. C. Hurt: Temperature-sensitive mutations demonstrate roles for yeast fibrillarin in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. Cell 72, 443-457 (1993).

53. Ralf Jansen, David Tollervey and Eduard C. Hurt: A U3 snoRNP Protein with Homology to Splicing Factor PRP4 and GβDomains is Required for Ribosomal RNA Processing. EMBO J. 12, 2549-2558 (1993).

54. P. Grandi, V. Doye and E. C. Hurt: Purification of NSP1 reveals complex formation with 'GLFG' nucleoporins and a novel nuclear pore protein NIC96. EMBO J. 12 3061-3071 (1993).

55. Eduard C. Hurt: The nuclear pore complex. FEBS Lett. 325, 76-80 (1993).

56. U. Nehrbass, E. Fabre, S. Dihlmann, W. Herth and E.C. Hurt: Analysis of nucleo-cytoplasmic transport in a thermo-sensitive mutant of nuclear pore protein NSP1. Eur. J. Cell Biol. 62, 1-12 (1993).

57. G. Schlenstedt, E. C. Hurt, V. Doye and P. A. Silver: Reconstitution of nuclear protein transport with semi-intact yeast cells. J. Cell Biol. 123, 785-798 (1993).


58. E. Fabre and E. C. Hurt: Nuclear transport. Curr. Opin. Cell Biol. 6, 335-342 (1994).

59. T. Berges, E. Petfalski, D. Tollervey and E. C. Hurt: Synthetic lethality with fibrillarin idenitifies NOP77p, a nucleolar protein required for pre-rRNA pprocessing and modification. EMBO J. 13, 3136-3148 (1994).

60. E. Fabre, W. C. Boelens, C. Wimmer, I. Mattaj and E. C. Hurt: Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motif. Cell 78, 275 - 289 (1994).

61. V. Doye, R. Wepf and E. C. Hurt: A novel nuclear pore protein Nup133p with Distinct Roles in poly(A)+ RNA Transport and Nuclear Pore Distribution EMBO J. 13, 6062 - 6075 (1994).


62. P. Grandi, N. Schlaich, H. Tekotte and E. C. Hurt: Functional interaction of Nic96p with a core nucleoporin complex consisting of Nsp1p, Nup49p and a novel protein Nup57p. EMBO J. 14, 76 - 87 (1995).

63. N. L. Schlaich and E. C. Hurt: Disruption of the gene coding for the nuclear pore protein Nup1p leads to nuclear accumulation of poly(A)+ RNA. Eur. J. Cell Biol. 67, 8 -14 (1995).

64. V. Doye and E. C. Hurt: Genetic approaches to nuclear pore structure and function Trends Genet. 11, 193-199 (1995).

65. P. Grandi, S. Emig, C. Weise, F. Hucho, T. Pohl and E. C. Hurt: A novel nuclear pore protein Nup82p which specifically binds to a fraction of Nsp1p J. Cell Biol.130, 1263-1273 (1995).

66. P. Grandi and E. C. Hurt: The nuclear pore complex in yeast. In Membrane Protein Transport. Editor S. S. Rothman, Jai Press Ltd., Vol. 2, 29-56 (1995).

67. G. Simos and E. C. Hurt: Nucleocytoplasmic transport - factors and mechanisms FEBS Lett. 369, 107-112 (1995).


68. K. Sharma, E. Fabre, H. Tekotte, E. C. Hurt and D. Tollervey: Yeast nucleoporin mutants are defective in pre-tRNA splicing. Mol. Cell. Biol. 16, 294-301 (1996).

69. G. Simos, H. Tekotte, H. Grosjean, A. Segref, K. Sharma, D. Tollervey and E. C. Hurt: Nuclear Pore Proteins are Required for the Biogenesis of Functional tRNA EMBO J. 15, 2285-2290 (1996).

70. U. Zabel, V. Doye, H. Tekotte, R. Wepf and E. C. Hurt: Nic96p is Required for Nuclear Pore Formation and Functionally Interacts with a Novel Nucleoporin, Nup188p. J. Cell Biol. 133, 1141- 1152 (1996).

71. S. Siniossoglou, C. Wimmer, M. Rieger, V. Doye, H. Tekotte, C. Weise, S. Emig, A. Segref and E. C. Hurt: A Novel Complex of Nucleoporins which Includes Sec13p and a Sec13p Homologue is Essential for Normal Nuclear Pores. Cell 84, 265-275 (1996).

72. E. C. Hurt: Importins/karyopherins meet nucleoporins. Cell 84, 509-515 (1996).

73. E. Fabre, N. Schlaich and E. C. Hurt: Nucleocytoplasmic Trafficking: what role for repeated motifs in Nucleoporins? Cold Spring Harbor Symposia on Quantitative Biology, Volume LX, 677-685 (1995).

74. G. Simos, A. Segref, F. Fasiolo, K. Hellmuth, A. Shevshenko, M. Mann and E. C. Hurt: The Yeast Protein Arc1p Binds to tRNA and Functions as a Cofactor for the Methionyl- and Glutamyl-tRNA Synthetases EMBO J. 15, 5437 - 5448 (1996).

75. G. Vitale, E. Fabre and E. C. Hurt: NBP35 Encodes an Essential and Evolutionary Conserved Protein in Saccharomyces cerevisiae with Homology to a Superfamily of Bacterial ATPases Gene 178, 97 - 106 (1996).

76. I. Irminger-Finger, E. C. Hurt, A. Roebuck, M. A. Collart, and S. J. Edelstein: MHP1, an essential gene in Saccharomyces cervisiae required for microtubule function J. Cell Biology 135, 1323 - 1340 (1996).


77. N. L. Schlaich, M. Häner, U. Aebi, and E. C. Hurt: In Vitro Reconstitution of a Heterotrimeric Nucleoporin Complex Consisting of Recombinant Nsp1p, Nup49p and Nup57p Mol. Biol. Cell 8, 33 - 46 (1997).

78. A. Segref, K. Sharma, V. Doye, A. Hellwig, J. Huber, R. Lührmann and E. C. Hurt: Mex67p, A Novel Factor for Nuclear mRNA Export, Binds to Both Poly(A)+ RNA and Nuclear Pores EMBO J. 11, 3256 - 3271 (1997).

79. P. Grandi, T. Dang, N. Panté, A. Shevchenko, M. Mann, D. Forbes and E. C. Hurt: Nup93, a Vertebrate Homolog of Yeast Nic96p, forms a Complex with a Novel 205 kDa Protein and is Required for Correct Nuclear Pore Assembly Mol. Biol. Cell., 8, 2017 - 2038 (1997).

80. M. T. Teixeira, S. Siniossoglou, S. Podtelejnikov, J.-C. Bénichou, M. Mann, E. Hurt and E. Fabre: Two Functionaly Distincts Domains Generated by in vivo Cleavage of Nup145p: a Novel Biogenesis Pathway for Nucleoporins EMBO J. 16, 5086 - 5097 (1997).

81. V. Doye and E. C. Hurt: From Nucleoporins to Nuclear Pore Complexes Curr. Opin. Cell Biol. 9, 401 - 411 (1997).

82. T. Gautier, T. Bergès, D. Tollervey and E. C. Hurt: Nucleolar KKE/D Repeat Proteins Nop56p and Nop58p Interact with Nop1p and Are Required for Ribosome Biogenesis Mol. Cell. Biol. 17, 7088-7098 (1997).

83. E. Fabre and E. C. Hurt: Yeast genetics to dissect the nuclear pore complex and nucleocytoplasmic trafficking Ann. Rev. Genet. 31, 277-313 (1997).


84. François Lecointe, George Simos, Anke Sauer, Eduard C. Hurt, Yuri Motorin and Henri Grosjean: Characterization of yeast protein Deg1 as Pseudouridine synthase (Pus3) catalyzing the formation of 38 and  39 in tRNA anticodon loop J. Biol. Chem. 273, 1316-1323 (1998)

85. S. Siniossoglou, P. Grandi, E. C. Hurt: Affinity Purification of Protein A-Tagged Nuclear Pore Proteins from Yeast Cell Biology: A Laboratory Hand Book. Academic Press. Second Edition. Vol. 2, 159 - 164 (1998).

86. George Simos, Anke Sauer, Franco Fasiolo and Eduard C. Hurt: A tRNA-binding domain within Arc1p delivers tRNA to two aminoacyl-tRNA synthetases Molecular Cell 1, 235 - 242 (1998).

87. Susanne Bailer, Symeon Siniossoglou, Sasha Podtelejnikov, Andrea Hellwig, Matthias Mann and Ed Hurt: Nup116p and Nup100p are Interchangeable through a Conserved Motif which Constitutes a Docking Site for the mRNA Transport Factor Gle2p/Nup40p EMBO J. 17, 1107-1119 (1998).

88. Bruno Senger, George Simos, F. Ralf Bischoff, Alexandre Podtelejnikov, Matthias Mann and Ed Hurt: Mtr10p Functions as a Nuclear Import Receptor for the mRNA Binding Protein Npl3p EMBO J. 17, 2196 - 2207 (1998).

89. Helena Santos-Rosa, Horacio Moreno, George Simos, Alexandra Segref, Birthe Fahrenkrog, Nelly Panté, and Ed Hurt: Nuclear mRNA Export Requires Complex Formation between Mex67p and Mtr2p at the Nuclear Pores Mol. Cell. Biol. 18, 6826-6838 (1998).

90. Klaus Hellmuth, Denise Lau, Ralf Bischoff, Markus Künzler, Ed Hurt and George Simos: Yeast Los1p Has Properties of an Exportin-Like Nucleocytoplasmic Transport Factor for tRNA Mol. Cell. Biol. 18, 6374-6386 (1998).

91. Ed Hurt: 'Rush Hour' an den Ein- und Ausfallstraßen des Zellkerns Kernporen kontrollieren den gesamten Verkehr durch die Kernhülle Ruperto Carola 1, 12 -17 (1998).

92. Y. Motorin, G. Keith, C. Simon, D. Foiret, G. Simos, E. Hurt, and H. Grosjean: Yeast tRNA: pseudouridine synthase (Pus1p) displays a multisite substrate specificity RNA 4, 856 - 869 (1998)

93. Birthe Fahrenkrog, Eduard C. Hurt, Ueli Aebi, and Nelly Panté: Molecular Architecture of the Yeast Nuclear Pore Complex: Localization of Nsp1p Subcomplexes J. Cell Biol. 143, 577 – 588 (1998).

94. Markus Künzler and Ed Hurt: Functional conservation between Saccharomyces cerevisiae Cse1p and CAS, the human nuclear export receptor for α-importin FEBS Lett. 433, 185-190 (1998).

95. Ed Hurt and Günther Schütz: Nuclear compartments and nuclear machines Curr. Opin. Cell Biol. 10, 301 - 303 (1998).

96. Symeon Siniossoglou, Helena Santos-Rosa, Juri Rappsilber, Mathias Mann and Ed Hurt: A Novel Complex of Membrane Proteins Required for Formation of a Spherical Nucleus EMBO J. 17, 6449-6464 (1998).


97. S. Massenet, Y. Motorin, E. Hurt, H. Grosjean and C. Branlant: Pseudouridine Mapping in the Yeast spliceosomal UsnRNAs Reveals that Pseudouridine Synthase Pus1p Exhibits a Dual Substrate Specificity for U2 snRNA and tRNA Mol. Cell. Biol. 19, 2142-2154 (1999).

98. Ed Hurt, Stefan Hannus, Birgit Schmelzl, Denise Lau, David Tollervey and George Simos: A Novel In Vivo Assay Reveals Inhibition of Ribosomal Nuclear Export in Ran-Cycle and Nucleoporin Mutants J. Cell Biol. 144, 389-401 (1999).

99. J. Katahira, Katja Sträßer, A. Podtelejnikov, M. Mann, J. U. Jung and E. C. Hurt: The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human EMBO J. 18, 2593-2609 (1999).

100. Kaja Sträßer and Ed Hurt: Nuclear export of mRNA in yeast FEBS Lett. 452, 77-81 (1999).

101. George Simos and Ed Hurt: tRNA aminoacylation - a visa to leave the nucleus Curr. Biol. 9, R238-R241 (1999).

102. Buket Kosova, Nelly Panté, Christiane Rollenhagen and Ed Hurt: Nup192p is a Conserved Nucleoporin with a Preferential Location at the Inner Site of the Nuclear Membrane J. Biol. Chem. 274, 22646-22651 (1999).


103. Helge Großhans, Ed Hurt and George Simos: An aminoacylation-dependent nuclear tRNA export pathway in yeast involves protein translation factor EF-1a Genes &. Develop. 14, 830-840 (2000).

104. Ed Hurt, Katja Sträßer, Alexandra Segref, Nick Schlaich, Carlo Presutti, David Tollervey and Ralf Jansen: Mex67p Mediates the Nuclear Export of a Variety of Pol II Transcripts J. Biol. Chem. 275, 8361-8368 (2000).

105. Buket Kosova, Nelly Panté, Christiane Rollenhagen, Helena Santos-Rosa, Alexandre Podtelejnikov, Matthias Mann, Ueli Aebi and Ed Hurt: Mlp2p, a Component of Nuclear Pore Attached Intranuclear Filaments, Associates with Nic96p J. Biol. Chem. 275, 343-350 (2000).

106. Denise Lau, Markus Künzler, Klaus Hellmuth, Alexandre Podtelejnikov, Matthias Mann and Ed Hurt: Purification of ProteinA-Tagged Yeast Ran Reveals Association with a Novel Karyopherin β Family Member Pdr6p J. Biol. Chem. 275, 467-471(2000).

107. Katja Sträßer and Ed Hurt: A Non-Shuttling Nuclear RNA Annealing Protein, which Directly Interacts with Mex67p, is Essential for mRNA Export EMBO J. 19, 420-428 (2000).

108. Juri Rappsilber, Symeon Siniossoglou, Eduard C. Hurt and Matthias Mann: A Generic Strategy to Analyze the Spatial Organization of Multi-Protein Complexes by Cross-Linking and Mass Spectrometry Anal. Chem.72, 267-75 (2000).

109. Susanne Bailer, Carolin Balduf, Jun Katahira, Alexandre Podtelejnikov, Christiane Rollenhagen, Matthias Mann, Nelly Panté and Ed Hurt: Nup116p associates with the Nup82p-Nsp1p-Nup159p nucleoporin complex J. Biol. Chem. 275, 23540-23548 (2000).

110. Helge Grosshans, George Simos, and Ed Hurt: Transport of tRNA Out of the Nucleus - Direct Channeling to the Ribosome? J. Struct. Biol.129, 288-294 (2000). 111. Markus Künzler, Thomas Gerstberger, Francoise Stutz, and Ed Hurt: Yeast Ran-binding protein 1 (Yrb1) shuttles between nucleus and cytoplasm and is exported from the nucleus via a CRM1 (XPO1)-dependent pathway Mol. Cell Biol. 20, 4295-4308 (2000).

112. Symeon Siniossoglou, Malik Lutzmann, Helena Santos-Rosa, Kevin Leonard, Shirley Mueller, Ueli Aebi and Ed Hurt Structure and Assembly of the Nup84p Complex J. Cell. Biol. 149, 41-53 (2000).

113. Katja Sträßer, Jochen Bassler and Ed Hurt: Binding of the Mex67p/Mtr2p Heterodimer to FXFG-, GLFG-, and FG-Repeat Nucleoporins is Essential for Nuclear mRNA Export J. Cell Biol., 150, 695-706 (2000). 133. Birthe Fahrenkrog, John Aris, Ed Hurt, Nelly Panté and Ueli Aebi: Comparative spatial localization of Protein-A-tagged and authentic yeast nuclear pore complex proteins by immunogold electron microscopy J. Struct. Biol.129, 295-305 (2000).

115. Symeon Siniossoglou, Ed Hurt and Hugh R. B. Pelham: Psr1p/Psr2p, two plasma membrane phosphatases with an essential DXDX(T/V) motif required for sodium stress response in yeast J. Biol. Chem. 275, 19352-19360 (2000).

116. Klaus Hellmuth, Yuri Motorin, Henri Grosjean and Ed Hurt: The Schizosaccharomyces pombe Protein Lps1p, a Homologue of Saccharomyces cerevisiae Pus1p, Functions as a Pseudouridine Synthase for tRNA Nuc. Acid Res. 28, 4604-4610 (2000).

117. Zhaolan Zhou, Ming-juan Luo, Katja Sträßer, Jun Katahira, Ed Hurt and Robin Reed: The protein ALY links pre-messenger-RNA splicing to nuclear export in metazoans Nature, 407, 401-405 (2000).

118. Natalia Gomez-Ospina, Garry Morgan, Thomas H. Giddings Jr., Buket Kosova, Ed Hurt and Mark Winey: Yeast Nuclear Pore Complex Assembly Defects Determined by Nuclear Envelope Reconstruction J. Struct. Biol. 132, 1-5 (2000).


119. Karina Deinert, Franco Fasiolo, Eduard C. Hurt, and Geoorge Simos: Arc1p organizes the yeast aminoacyl-tRNA synthetase complex and stabilizes its interaction with cognate tRNAs J. Biol. Chem., 276, 6000-6008 (2001).

120. Olivier Gadal, Daniela Strauss, Jacques Kessl, Bernard Trumpower, David Tollervey and Ed Hurt: Nmd3p functions as a nuclear adaptor for Xpo1p-dependent export of 60S ribosomal subunits Mol. Cell. Biol. 21, 3405-3415 (2001).

121. Helge Großhans, Karina Deinert, Ed Hurt and George Simos: Biogenesis of the Signal Recognition Particle Requires Nuclear Import of SRP proteins, Assembly with the SRP-RNA in the Nucleolus, and Xpo1p-mediated Nuclear Export J. Cell Biol., 153, 745-751 (2001).

122. Susanne M. Bailer, Carolin Balduf, and Ed Hurt: The Nsp1p carboxy-terminal domain is organized into functionally distinct coiled-coil regions required for assembly of nucleoporin subcomplexes and nucleocytoplasmic transport Mol. Cell. Biol., 21, 7944-7955 (2001).

123. Philipp Milkereit, Olivier Gadal, Alexander Podtelejniko V., Stephanie Trumtel, Nicole Gas, Elisabeth Petfalski, David Tollervey, Mathias Mann, Ed Hurt and Herbert Tschochner: Maturation of Pre-Ribosomes Requires Noc-Proteins and is Coupled to Transport from the Nucleolus to the Nucleoplasm Cell 105, 499-509 (2001).

124. Markus Künzler and Ed Hurt: Targeting of Ran: variation on a common theme? J. Cell Sci. 114, 3233-3241 (2001). 125. Olivier Gadal, Joris Braspenning, Daniela Strauß, Dominic Hoepfner, Elisabeth Petfalski, Peter Philippsen, David Tollervey and Ed Hurt: A nuclear AAA-type ATPase (Rix7p) is required for large ribosomal subunit biogenesis and subsequent export to the cytoplasm EMBO J. 20, 3695-3704 (2001).

126. Katja Sträßer and Ed Hurt: The splicing factor Sub2p interacts directly with the mRNA transport factor Yra1p and is required for nuclear mRNA export Nature 413, 648-652 (2001).

127. Künzler M., Trueheart J., Sette C., Hurt E., Thorner J.: Mutations in the YRB1 Gene Encoding Yeast Ran-Binding-Protein-1 That Impair Nucleocytoplasmic Transport and Suppress Yeast Mating Defects Genetics 157, 1089-1105 (2001).

128. B. Senger, D. Lafontaine, O. Gadal, J. Graindorge, A. Camasses, A.Sanni, J. Garnier, M. Breitenbach , E. Hurt, and F. Fasiolo: Elongation factor like-1, a cytoplasmic GTPase homologous to the ribosomal translocases EF-G/EF-2 is required for ribosome export and a late cytoplasmic step of ribosomal assembly Molecular Cell, 8, 1363–1373 (2001).

129. Jochen Baßler, Paola Grandi, Olivier Gadal, Torben Leßmann, David Tollervey, Johannes Lechner, and Ed Hurt: Identification of a 60S pre-ribosomal particle that is closely linked to nuclear export Molecular Cell 8, 517-529 (2001).

130. K. Galani, H. Großhans, Deinert, K., E. C. Hurt,and G. Simos: Regulation of intracellular location of aminoacyl-tRNA-synthetases by complex formation with Arc1p EMBO J. 20, 6889-6898 (2001).

131. Helge Großhans, Helge Großhans, Francois Lecointe, Henri Grosjean Ed Hurt, and George Simos: Pus1p-dependent tRNA pseudouridinylation becomes essential when tRNA biogenesis is compromised in yeast J. Biol. Chem. 276, 46333-46339 (2001).


132. Jun Katahira, Katja Straesser, Takuya Saiwaki, Yoshihiro Yoneda, and Ed Hurt: Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling J. Biol. Chem., 277, 9242-9246 (2002).

133. Malik Lutzmann, Ruth Kunze, Andrea Buerer, Ueli Aebi and Ed Hurt: Modular Self-Assembly of a Y-Shaped Multiprotein Complex from Seven Nucleoporins EMBO J. 21, 387-397 (2002).

134. Richard Grant , Ed Hurt, David Neuhaus and Murray Stewart: Structure of the C-terminal FG-Nucleoporin binding domain of Tap/NXF1 Nat. Struct. Biol. 9, 247-251 (2002).

135. Susana Rodríguez-Navarro, Katja Sträßer and Ed Hurt: An intron in the YRA1 gene is required to control Yra1p protein expression and mRNA export EMBO Rep. 3, 438-442(2002).

136. Robin Reed and Ed Hurt: A conserved mRNA export machinery coupled to pre-mRNA splicing Cell 108, 523-531 (2002).

137. Katja Sträßer, Seiji Masuda, Paul Mason, Jens Pfannstiel, Marisa Oppizzi, Susana Rodriguez-Navarro, Ana G. Rondón, Andres Aguilera, Kevin Struhl, Robin Reed, and Ed Hurt: TREX is a conserved complex coupling transcription with mRNA export Nature 417, 304-308 (2002).

138. Olivier Gadal, Daniela Strauß, Elisabeth Petfalski, Pierre-Emmanuel Gleizes, Nicole Gas, David Tollervey, and Ed Hurt: Rlp7p is associated with 60S pre-ribosomes, restricted to the granular component of the nucleolus and required for pre-rRNA processing J. Cell Biol. 157, 941-951 (2002).

139. Paola Paola Grandi, Vladimir Rybin, Jochen Baßler, Elisabeth Petfalski, Daniela Strauß, Martina Marzioch, Thorsten Schäfer, Bernhard Kuster, Herbert Tschochner, David Tollervey, Anne-Claude Gavin and Ed Hurt: 90S Pre-Ribosomes Include the 35S Pre-rRNA, the U3 snoRNP and 40S Subunit Processing Factors but Predominately lack 60S Synthesis Factors Mol. Cell 10, 105-115 (2002).

140. Simos G, Grosshans H, Hurt E.: Nuclear export of tRNA Results Probl. Cell Differ. 35, 115-31 (2002).

141. Tamás Fischer, Katja Sträßer, Attila Rácz, Susana Rodriguez-Navarro, Marisa Oppizzi, Petra Ihrig and Ed Hurt: The conserved mRNA export machinery requires the Sac3-Thp1 complex to dock to nucleoporins at nucleoplasmic entrance of the nuclear pores EMBO J., 21, 5843-5852 (2002).

142. Tracy A. Nissan, Jochen Baßler, Elisabeth Petfalski, Paola Grandi, David Tollervey, and Ed Hurt: The biochemistry of 60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm EMBO J. 21, 5539-5547(2002).

143. Nadia Allen, Samir Patel, Lan Huang, Robert Chalkley, Al Burlingame, Malik Lutzmann, Eduard C. Hurt and Michael Rexach: Deciphering Networks of Protein Interactions at the Nuclear Pore Complex Mol. Cell Proteomics 1, 930-496 (2002)


144. Vikram Panse and Ed Hurt: Unconventional tethering of the SUMO-1 deconjugating enzyme Ulp1 to nuclear pore transport channel via karyopherins Nat. Cell. Biol. 5, 21-27 (2003).

145. Herbert Tschochner and Ed Hurt: Pre-Ribosomes on the Road from the Nucleolus to the Cytoplasm Trends Cell Biol. 13, 255-263 (2003).

146. Philipp Milkereit, Daniela Strauß, Jochen Baßler, Olivier Gadal, Holger Kühn, Sylvia Schütz, Johannes Lechner, Ed Hurt and Herbert Tschochner: A Noc-complex specifically involved in maturation and nuclear export of ribosomal 40S subunits J. Biol. Chem. 278, 4072-4081 (2003).

147. Andreas Braunwarth, Michel Fromont-Racine, Pierre Legrain , Ral f Bischoff, Thomas Gerstberger, Ed Hurt and Markus Künzler:Identification and characterization of a novel RanGTP binding protein Yrb30 J. Biol. Chem. 278, 15397-15405 (2003).

148. Thorsten Schäfer, Daniela Strauß, Elisabeth Petfalski, David Tollervey and Ed Hurt: The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes EMBO J. 22, 1370-1380 (2003).

149. Silvia Neumann, Elisabeth Petfalski, Britta Brügger, Helge Großhans, Felix Wieland, David Tollervey and Ed Hurt: Formation and nuclear export of tRNA, rRNA and mRNA is regulated by the ubiquitin ligase Rsp5p. EMBO Rep. 4, 1156-1162 (2003).


150. Susana Rodriguez-Navarro, Tamás Fischer, Ming-Juan Luo, Oreto Antunez, Susanne Brettschneider, Jose E. Perez-Ortin, Robin Reed, and Ed Hurt: Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery Cell 116, 75-86 (2004).

151. Tracy A. Nissan, Kyriaki Galani, Bohumil Maco, David Tollervey, Ueli Aebi and Ed Hurt: A nascent pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits Mol. Cell 15, 295-301 (2004)

152. Ed Hurt, Ming-juan Luo, Susanne Röther, Robin Reed and Katja Sträßer: Co-transcriptional recruitment of the SR-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex Proc. Natl. Aca. Sci. USA, 101, 1858-1862 (2004).

153. Francesca Saracino, Jochen Baßler, Diego Muzzini, Ed Hurt and Maria Luisa Agostoni Carbone: The Yeast Kinase Swe1 is Required for proper Entry into a new Cell Cycle after Arrest due to Ribosome Biogenesis Defects Cell Cycle 3, 648-54 (2004).

154. Vikram Govind Panse, Ulrike Hardeland, Thilo Werner, Bernhard Küster and Ed Hurt:A proteome-wide approach identifies sumolyated substrate proteins in yeast J. Biol. Chem. 279, 41346-41351 (2004).

155. Kyriaki Galani, Tracy A. Nissan, Elisabeth Petfalski, David Tollervey and Ed Hurt: Rea1, a dynein-related nuclear AAA-type ATPase, is involved in late 25S rRNA processing and nuclear export of 60S subunits J. Biol. Chem. 279, 55411-55418 (2004).

156. Tamas Fischer, Susana Rodriguez-Navarro, Elmar Schiebel and Ed Hurt: Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery Nat. Cell Biol. 6, 840—848 (2004).


157. Kyriaki Galani, Eduard C. Hurt and George Simos: The tRNA aminoacylation co-factor Arc1p is excluded from the nucleus by an Xpo1p-dependent mechanism FEBS Lett. 579, 969-975 (2005).

158. Alexander Yarunin, Vikram Panse, Elisabeth Petfalski, Christophe Dez, David Tollervey and Ed Hurt: Functional link between ribosome formation and biogenesis of iron-sulfur proteins EMBO J. 24, 580-588 (2005).

159. Malik Lutzmann, Ruth Kunze, Karin Stangl, Philipp Stelter, Katalin Fejes Tóth, Bettina Boettcher and Ed Hurt: Reconstitution of Nup157 and Nup145N into the Nup84 complex J. Biol. Chem. 280, 18442-18451 (2005).

160. Seiji Masuda, Rita Das, Ed Hurt, Nijsje Dorman and Robin Reed: Recruitment of the human TREX complex to mRNA during splicing Genes and Develop.19, 1512-1517 (2005).


161. Thorsten Schäfer, Bohumil Maco, Elisabeth Petfalski, David Tollervey, Bettina Boettcher, Ueli Aebi and Ed Hurt: A round of phosphorylation/de-phosphorylation triggers maturation of the pre-ribosomal 40S subunit Nature 441, 651-655 (2006).

162. Ghislain Cabal, Susana Rodrigez-Navarro, August Genevesio, Jean-Christophe Olivo-Marin, Christophe Zimmer, Olivier Gadal, Frank Feuerbach-Fournier, Annick Lesne, Henri Buc, Ed Hurt* and Ulf Nehrbass* (*corresponding authors): Molecular Analysis of SAGA Mediated Gene Gating In Yeast Nature 441, 770-773 (2006).

163. Alwin Köhler, Pau Pascual-García, Ana Llopis, Meritxell Zapater, Francesc Posas, Ed Hurt and Susana Rodríguez-Navarro: The mRNA Export Factor Sus1 Is Involved in SAGA-mediated H2B Deubiquitinylation through Its Interaction with Ubp8 and Sgf11 Mol. Biol. Cell. 17, 4228-4236 (2006).

164. Vikram Govind Panse, Dieter Kressler, Andrea Pauli, Elisabeth Petfalski, Marén Gnädig, David Tollervey and Ed Hurt: Formation and nuclear export of pre-ribosomes are functionally linked to the small-ubiquitin-related (SUMO) modifier pathway Traffic 7, 1311-1321 (2006).

165. Jochen Baßler, Martina Kallas and Ed Hurt: The Nug1 GTPase reveals an N-terminal RNA binding domain that is essential for association with pre-60S subunits. J. Biol. Chem. 281, 24737-24744 (2006).

166. Yoshimi Honma, Aiko Kitamura, Ryo Shioda, Hironori Maruyama, Kanako Ozaki, Yoko Oda, Thierry Mini, Paul Jen, Yasushi Maki, Kazuhito Yonezawa, Ed Hurt, Masaru Ueno, Masahiro Uritani, Michael N. Hall, and Takashi Ushimaru: TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients EMBO J. 25, 3832-3842 (2006).

167. Ulrike Hardeland and Ed Hurt: Coordinated nuclear import of RNA polymerase III subunits Traffic 7, 465-473 (2006).


168. Bettina Bradatsch, Jun Katahira, Eva Kowalinski, Gert Bange, Wei Yao, Toshihiro Sekimoto, Viola Baumgärtel, Guido Boese, Jochen Bassler, Klemens Wild, Reiner Peters, Yoshihiro Yoneda, Irmi Sinning and Ed Hurt: Arx1 functions as alternative nuclear export receptor for the 60S pre-ribosomal subunit Mol. Cell 27, 767-779 (2007).

169. Philipp Stelter, Ruth Kunze, Dirk Flemming, Dominic Höpfner, Meikel Diepholz, Peter Philipsen, Bettina Böttcher and Ed Hurt: Molecular basis for the functional interaction of dynein light chain with the nuclear pore complex Nature Cell Biology 9, 788-769 (2007).

170. Wei Yao, Daniela Roser, Alwin Köhler, Bettina Bradatsch, Jochen Baßler and Ed Hurt: Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2 Mol. Cell 26, 51-62 (2007).

171. Eva Kowalinski, Gert Bange, Bettina Bradatsch, Ed Hurt, Klemens Wild and Irmi Sinning. The crystal structure of Ebp1 reveals how the methionine aminopeptidase fold serves as a binding platform for multiple interactions FEBS Lett. 581, 4450-4454 (2007).

172. Alwin Köhler and Ed Hurt: Exporting RNA from the nucleus to the cytoplasm Nature Rev. Mol. Cell Biol. 8, 761-773 (2007).

173. Vikram Govind Panse and Ed Hurt: Adjunct duties for karyopherins: Regulating septin sumoylation Dev. Cell 12, 669-670 (2007).


174. Wei Yao, Malik Lutzmann and Ed Hurt: A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export EMBO J. 27, 6–16 (2008).

175. Nils Schrader, Philipp Stelter, Dirk Flemming, Ruth Kunze, Ed Hurt* and Ingrid Vetter* (*corresponding authors): Structural basis of the Nic96 subcomplex organization in the nuclear pore channel Mol. Cell 29, 46-55 (2008).

176. Alwin Köhler, Maren Schneider, Ghislain Cabal, Ulf Nehrbass and Ed Hurt: An integrative role of Sgf73 in multiple steps of SAGA-dependent gene gating Nat. Cell Biol. 10, 707-15 (2008).

177. Dieter Kressler, Daniela Roser, Brigitte Pertschy and Ed Hurt: The AAA-ATPase Rix7 powers progression of ribosome biogenesis by stripping Nsa1 from pre-60S particles J. Cell Biol. 181, 835-844 (2008).

178. Stefanie Grund, Tamas Fischer, Ghislain G. Cabal, Oreto Antúnez, José E. Pérez-Ortín and Ed Hurt: The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression J. Cell Biol. 182, 897-910 (2008).

179. Rainer Beck, Zhe Sun, Frank Adolf, Chistoph Rutz, Jochen Baßler, Klemens Wild, Irmgard Sinning, Ed Hurt, Britta Brügger, Julien Béthune and Felix Wieland: Membrane curvature induced by GTP-dependent dimerization of Arf1 is essential for vesicle formation Proc. Natl. Aca. Sci. USA 105, 11731-11736 (2008).

180. Ed Hurt: “Der Kernporenkomplex oder das Tor zur Welt des Zytoplasmas” im Jahrbuch 2007 der Deutschen Akademie der Naturforscher Leopoldina Leopoldina 53, 457-460 (2008).


181. Dirk Flemming, Philipp Sarges, Philipp Stelter, Andrea Hellwig, Bettina Boettcher and Ed Hurt: Two structurally distinct domains of the nucleoporin Nup170 cooperate to tether a subset of nucleoporins to nuclear pores J. Cell Biol. 185, 387-395 (2009).

182. Thierry Lacombe, Juan J. García-Gómez, Jesús de la Cruz, Daniela Roser, Ed Hurt, Patrick Linder and Dieter Kressler: Linear ubiquitin fusion to Rps31 and its subsequent cleavage 1 are required for the efficient production and functional integrity of 40S ribosomal subunits Mol. Microbiol. 72, 69-84 (2009).

183. Lindsay S. Garrenton, Andreas Braunwarth, Stefan Irniger, Ed Hurt, Markus Künzler and Jeremy Thorner: Nucleus-Specific and Cell Cycle-Regulated Degradation of MAPK Scaffold Protein Ste5 Contributes to the Control of Signaling Competence Mol. Cell Biol. 29, 582-601 (2009).

184. Michal Skruzny, Claudia Schneider, Attila Rácz, Julan Weng, David Tollervey and Ed Hurt: An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes PLoS Biology 7, e8 (2009).

185. Jun Katahira, Hitomi Inoue, Ed Hurt, Yoshihiro Yoneda: The adaptor Aly and co-adaptor Thoc5 function in Tap-p15 mediated nuclear export of HSP70 mRNA EMBO J. 28, 556-567 (2009).

186. Divyang Jani, Sheila Lutz, Neil J. Marshall, Tamas Fischer, Alwin Köhler, Andrew M. Ellisdon, Ed Hurt and Murray Stewart: Sus1, Cdc31 and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export Mol. Cell 33, 727-737 (2009).

187. Marius Boulos Faza, Stefan Kemmler, Sonia Jimeno, Christina González-Aguilera, Andres Aguilera, Ed Hurt and Vikram Govind Panse: Sem1 is a functional component of the nuclear pore complex associated mRNA export machinery J. Cell Biol. 184, 833-846 (2009).

188. Christoph Klöckner, Maren Schneider, Sheila Lutz, Dieter Kressler, Divyang Jani, Murray Stewart, Ed Hurt and Alwin Köhler: Mutational Uncoupling of Sus1’s role in NPC-targeting of an mRNA Export Complex and Histone H2B deubiquitination J. Biol. Chem. 284, 12049-12056 (2009).

189. Sébastien Ferreira-Cerca and Ed Hurt: Arrest by Ribosome Nature 459, 46-47 (2009).

190. Cornelia Ulbrich, Meikel Diepholz, Jochen Baßler, Dieter Kressler, Brigitte Pertschy, Kiki Galani, Bettina Böttcher and Ed Hurt: Mechanochemical Removal of Ribosome Biogenesis Factors from Nascent 60S Ribosomal Subunits Cell 138, 911-922 (2009).

191. Brigitte Pertschy, Claudia Schneider, Maren Gnädig, Thorsten Schäfer, David Tollervey and Ed Hurt: RNA helicase Prp43 and its co-factor Pfa1 promote 20S to 18S rRNA processing catalyzed by the endonuclease Nob1 J. Biol. Chem. 284, 35079-35091 (2009).

192. Julien Batisse, Claire Batisse, Aidan Budd, Bettina Böttcher and Ed Hurt: Purification of poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein (mRNP) core structure J. Biol. Chem. 284, 34911-34917 (2009).

193. Gunes Bozkurt, Goran Stjepanovic, Fabio Vilardi, Stefan Amlacher, Klemens Wild, Gert Bange, Vincenzo Favaloro, Karsten Rippe, Ed Hurt, Bernhard Dobberstein and Irmgard Sinning: Structural insights into tail-anchored protein binding and membrane insertion by Get3 Proc. Natl. Acad. Sci. USA 106, 21131-21136 (2009).

194. Dieter Kressler, Ed Hurt and Jochen Bassler: Driving Ribosome Assembly Biochim. Biophys. Acta, in press (2009).

195. Andrew M. Ellisdon, Divyang Jani, Alwin Köhler, Ed Hurt and Murray Stewart: Structural basis for the Sus1:Sgf11 interaction in the yeast SAGA transcription activation complex J. Biol. Chem., in press (2009).


196. Alwin Köhler and Ed Hurt: Gene regulation by nucleoporins and links to cancer Mol. Cell, in press (2010).

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