Ulrich Dirnagl - Publications#


(Selected from last 4 year)

1. Neumann K, Grittner U, Piper SK, Rex A, Florez-Vargas O, Karystianis G, Schneider A, Wellwood I, Siegerink B, Ioannidis JP, Kimmelman J, Dirnagl U. (2017) Increasing efficiency of preclinical research by group sequential designs. PLoS Biol.15(3):e2001307

2. Holman C, Piper SK, Grittner U, Diamantaras AA, Kmmelman J, Siegerink B, Dirnagl U (2015) Where Have All the Rodents Gone? The Effects of Attrition in Experimental Research on Cancer and Stroke. Plos Biol 4(1):e1002331

3. Kopp MA, Watzlawick R, Martus P, Failli V, Finkenstaedt FW, Chen Y, DeVivo MJ, Dirnagl U, Schwab JM (2017) Long-term functional outcome in patients with acquired infections after acute spinal cord injury. Neurology. 88(9):892-900

4. Dirnagl U, Przesdzing I, Kurreck C, Major S. (2016) A laboratory critical incident and error reporting system for experimental biomedicine. Plos Biol 14: e2000705

5. Brommer B, Engel O, Kopp MA, Watzlawick R, Müller S, Prüss H, Chen Y, DeVivo MJ, Finkenstaedt FW, Dirnagl U, Liebscher T, Meisel A, Schwab JM (2016) A functional Spinal Cord injury-induced immune deficiency Syndrome propagates the susceptibility for bacterial infection in a lesion level dependent manner – neurogenic implications. Brain. pii: awv375

6. Begley CG, Buchan AM, Dirnagl U (2015). Robust research: Institutions must do their part for reproducibility. Nature 525:25-7.

7. Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, Dirnagl U, Grittner U, Planas AM, Plesnila N, Vivien D, Liesz A. (2015) Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia. Sci Transl Med. 7:299ra121

8. Kimmelman J, Mogil JS, Dirnagl U (2014) Distinguishing between exploratory and confirmatory preclinical research will improve translation. Plos Biol PLoS Biol 12(5): e1001863.

9. Dirnagl U, Endres M (2014) Found in translation - Preclinical stroke research predicts human pathophysiology, clinical phenotypes, and therapeutic outcomes. Stroke 2014; 45: 1510-1518

10.Macleod MR, Michie S, Roberts I, Dirnagl U, Chalmers I, Ioannidis JP, Al-Shahi Salman R, Chan A and Glasziou P (2014) Biomedical research: Increasing value, reducing waste. Lancet. 383:101-4.

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