Ernesto Carafoli - Selected publications#


  • Brini M, Carafoli E (2009) Calcium pumps in health and disease. Physiol. Rev. 89:1341-78.
  • Spiden SL, Bortolozzi M, Di Leva F, de Angelis MH, Fuchs H, Lim D, Ortolano S, Ingham NJ, Brini M, Carafoli E, Mammano F, Steel KP (2008) The novel mouse mutation Oblivion inactivates the PMCA2 pump and causes progressive hearing loss. PLoS Genet. 4:e1000238.
  • Lim D, Fedrizzi L, Tartari M, Zuccato C, Cattaneo E, Brini M, Carafoli E (2008) Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease. J. Biol. Chem. 283:5780-9.
  • Ficarella R, Di Leva F, Bortolozzi M, Ortolano S, Donaudy F, Petrillo M, Melchionda S, Lelli A, Domi T, Fedrizzi L, Lim D, Shull GE, Gasparini P, Brini M, Mammano F, Carafoli E (2007) A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness. Proc. Natl. Acad. Sci. U.S.A. 104:1516-21.
  • Bano D, Young KW, Guerin CJ, Lefeuvre R, Rothwell NJ, Naldini L, Rizzuto R, Carafoli E, Nicotera P (2005) Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity. Cell 120:275-85.
  • Bertipaglia I, Bourg N, Richard I, Pahlman AK, Andersson L, James P, Carafoli E (2009) A proteomic study of calpain-3 and its involvement in limb girdle muscular dystrophy type 2a. Cell Calcium 46:356-63.
  • Di Leva F, Domi T, Fedrizzi L, Lim D, Carafoli E (2008) The plasma membrane Ca2+ ATPase of animal cells: structure, function and regulation. Arch. Biochem. Biophys. 476:65-74.
  • Carafoli E, Klee CB (2008) A tribute to Dr. Setsuro Ebashi. Biochem. Biophys. Res. Commun. 369:28-9.
  • Linde CI, Di Leva F, Domi T, Tosatto SC, Brini M, Carafoli E (2008) Inhibitory interaction of the 14-3-3 proteins with ubiquitous (PMCA1) and tissue-specific (PMCA3) isoforms of the plasma membrane Ca2+ pump. Cell Calcium 43:550-61.
  • Brini M, Di Leva F, Domi T, Fedrizzi L, Lim D, Carafoli E (2007) Plasma-membrane calcium pumps and hereditary deafness. Biochem. Soc. Trans. 35:913-8.
  • Ficarella R, Di Leva F, Bortolozzi M, Ortolano S, Donaudy F, Petrillo M, Melchionda S, Lelli A, Domi T, Fedrizzi L, Lim D, Shull GE, Gasparini P, Brini M, Mammano F, Carafoli E (2007) A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness. Proc. Natl. Acad. Sci. U.S.A. 104:1516-21.
  • Rimessi A, Coletto L, Pinton P, Rizzuto R, Brini M, Carafoli E (2005) Inhibitory interaction of the 14-3-3{epsilon} protein with isoform 4 of the plasma membrane Ca(2+)-ATPase pump. J. Biol. Chem. 280:37195-203.
  • Saris NE, Carafoli E (2005) A historical review of cellular calcium handling, with emphasis on mitochondria. Biochemistry Mosc. 70:187-94.
  • Carafoli E (2005) The Symposia on Calcium Binding Proteins and Calcium Function in Health and Disease: an historical account, and an appraisal of their role in spreading the calcium message. Cell Calcium 37:279-81.
  • Carafoli E (2005) Calcium--a universal carrier of biological signals. Delivered on 3 July 2003 at the Special FEBS Meeting in Brussels. FEBS J. 272:1073-89.
  • Carafoli E (2004) Calcium signaling: a historical account. Biol. Res. 37:497-505.
  • Brini M, Manni S, Pierobon N, Du GG, Sharma P, MacLennan DH, Carafoli E (2005) Ca2+ signaling in HEK-293 and skeletal muscle cells expressing recombinant ryanodine receptors harboring malignant hyperthermia and central core disease mutations. J. Biol. Chem. 280:15380-9.
  • Carafoli E (2004) The ambivalent nature of the calcium signal. J. Endocrinol. Invest. 27:134-6.
  • Carafoli E (2004) Calcium-mediated cellular signals: a story of failures. Trends Biochem. Sci. 29:371-9.



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