David Baulcombe - Professional Interests#

My current research follows from the discovery in my Norwich laboratory of a novel type of regulatory RNA - siRNA. Current projects in the laboratory focus on the mechanisms of siRNA-mediated regulation and their influence on natural variation. In this respect, my work links with JS Henslow who was Professor of Botany in the nineteen century and who influenced Darwin. I am also interested in the influence of siRNA on heritable effects that do not involve changes to the sequence of the genome. Understanding these ‘epigenetic’ effects is central to any discussion about nurture and nature. Beyond the laboratory I promote the use of GM and other forms of plant biotechnology as part of a broad based strategy to improve agriculture.

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