Peter John Barnes - Selected publications#


Over 1,000 publications in peer reviewed journals; h-index = 133; most highly cited respiratory researcher in the world and 40th most cited scientist in the world over the last 20 years (ISA) and most highly cited respiratory researcher in Europe in last 10 years.
Author, editor/co-editor of >50 books on asthma, COPD, respiratory pharmacology and related topics.

1. Malhotra D, Thimmulappa RK, Mercado N, Ito K, Kombairaju P, Kumar S, Ma J, Feller-Kopman D, Wise R, Barnes P, Biswal S. Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients. J Clin Invest, 2011; 121:4289-4302
2. Barnes PJ. Pathophysiology of allergic inflammation. Immunol.Rev. 2011; 242:31-50.

3. To M, Ito K, Kizawa Y, Failla M, Ito M, Kusama T, Elliot M, Hogg JC, Adcock IM, Barnes PJ. Targeting phosphoinositide-3-kinase-δ with theophylline reverses corticosteroid insensitivity in COPD. Am J Resp Crit Care Med 2010; 182:897-904.

4. Salvi SS, Barnes PJ. Chronic obstructive pulmonary disease in non-smokers. Lancet 2009; 374: 733-743.

5. Maneechotesuwan K, Yao X, Ito K, Jazrawi E, Usmani OS, Adcock IM, Barnes PJ. Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease. PLoS Med. 2009; 6:e1000076.

6. Barnes PJ, Adcock IM. Glucocorticoid resistance in inflammatory diseases. Lancet 2009; 342:1905-1917.

7. Barnes PJ. Role of HDAC2 in the pathophysiology of COPD. Ann Rev Physiol, 2009; 71: 451-464.

8. Barnes PJ. Immunology of asthma and chronic obstructive pulmonary disease. Nat Immunol Rev 2008; 8:183-192.

9. Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ, Adcock IM. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression. J Exp Med 2006; 203:7-13.

10. Ito K, Ito M, Elliott WM, Cosio B, Caramori G, Kon OM, Barczyk A, Hayashi M, Adcock IM, Hogg JC, Barnes PJ. Decreased histone deacetylase activity and severity of chronic obstructive pulmonary disease. New Engl J Med, 2005; 352:1967-1976.
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