Lajos Kemeny - Publications#

MAJOR DISCOVERIES WITH HIGH IMPACT IN THE FIELD

BASIC RESEARCH. Description toll-like receptors in keratinocytes, their role in skin physiology and pathophysiology

1. Megyeri K, Orosz L, Bolla S, Erdei L, Razga Z, Seprenyi G, Urban E, Szabo K, Kemeny L: Propionibacterium acnes induces autophagy in keratinocytes: involvement of multiple mechanisms. JOURNAL OF INVESTIGATIVE DERMATOLOGY 138:(4) pp. 750-759. (2018) Discovery that P. acnes induces autophagy in keratinocytes. Cited by 8.

2. Szabó K , Erdei L , Bolla BS , Tax G , Biró T , Kemeny L: Factors shaping the composition of the cutaneous microbiota. Br J Dermatol 176: 344-351 (2017), A comprehensive review on the effect of microbiome in skin phisiology. Cited by 12.

3. Nagy I, Pivarcsi A, Kis K, Koreck A, Bodai L, McDowell A, Seltmann H, Patrick S, Zouboulis CC, Kemeny L: Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human sebocytes. MICROBES AND INFECTION 8:(8) pp. 2195-2205. (2006) Discovery that P. acnes modulates the functions of sebocytes. Cited by 231.

4. Nagy I, Pivarcsi A, Koreck A, Széll M, Urbán E, Kemény L: Distinct strains of Propionibacterium acnes induces selective human beta-defensin-2 and interleukin-8 expression in human keratinocytes through Toll-like receptors. JOURNAL OF INVESTIGATIVE DERMATOLOGY 124:(5) pp. 931-938. (2005) Discovery that different P.acnes strains have different effects on immune cells. Cited by 241.

5. Pivarcsi A, Nagy I, Koreck A, Kenderessy-Szabó A, Széll M, Dobozy A, Kemény L: Microbial compounds induce the expression of pro-inflammatory cytokines, chemokines and human beta-defensin-2 in vaginal epithelial cells. MICROBES AND INFECTION 7:(9-10) pp. 1117-1127. (2005) Discovery that microbial compounds affects the immune functions of vaginal epithelial cells. Cited by 110.

6. Pivarcsi A, Bodai L, Rethi B, Kenderessy Szabo A, Koreck A, Szell M, Beer Z, Bata Csorgo Z, Magocsi M, Rajnavolgyi E, Dobozy A, Kemeny L: Expression and function of Toll-like receptors 2 and 4 in human keratinocytes. INTERNATIONAL IMMUNOLOGY 15:(6) pp. 721-730. (2003) Discovery that human epithelial cells have functional toll-like receptors. Cited by 275.

TRANSLATIONAL RESEARCH. Identification of new treatment targets and development of new treatments for skin diseases

7. Manczinger M, Bodnar V, Papp BT, Bolla BS, Szabo K, Balazs B, Csanyi E, Szel E, Eros G, Kemeny L: Drug repurposing by simulating flow through protein-protein interaction networks. CLINICAL PHARMACOLOGY & THERAPEUTICS 103:(3) pp. 511-520. (2018) Development of a new method to find new treatment for skin diseases. Cited by 2.

8. Koreck AI, Csoma Z, Bodai L, Ignacz F, Kenderessy AS, Kadocsa E, Szabo G, Bor Z, Erdei A, Szony B, Homey B, Dobozy A, Kemeny L: Rhinophototherapy: A new therapeutic tool for the management of allergic rhinitis. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 115:(3) pp. 541-547. (2005) Development of a new, patented device and method for the treatment of allergic rhinitis. Cited by 56.

9. Baltás E, Csoma Zs, Ignacz F, Dobozy A, Kemény L: Treatment of vitiligo with the 308 nm xenon-chloride excimer laser. ARCHIVES OF DERMATOLOGY 138 (12) 1619-1921 (2004) Development of new treatment for vitiligo. Cited by 92.

10. Novák Z, Bónis B, Baltás E, Ocsovszki I, Ignácz F, Dobozy A, Kemény L: Xenon chloride ultraviolet B laser is more effective in treating psoriasis and inducing T cell apoptosis than narrow-band ultraviolet B. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY 67:(1) pp. 32-38. (2002) Development of a new treatment for psoriasis, and explanation for its high efficacy. Cited by 125.