!!Juleen Zierath - Publications
Juleen Zierath has published over 150 original research papers and review articles. She has an H-index of 50.
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__Major publications__
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1. Bouzakri, K., A. Zachrisson, L. Al-Khalili, B.B. Zhang, H. A. Koistinen,
A. Krook, and J. R. Zierath. siRNA Based gene silencing reveals specialized
roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human
skeletal muscle. Cell Metabolism, 4:89-96, 2006.
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2. Long, Y.C., S. Glund, P.M. Garcia-Roves, and J.R. Zierath. Calcineurin
regulates skeletal muscle metabolism via coordinated changes in gene expression.
J. Biol. Chem. 282:1607-1614, 2007.
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3. Bouzakri, K., and J.R. Zierath. MAP4K4 gene silencing in human skeletal
muscle prevents TNF-alpha-induced insulin resistance. J. Biol. Chem. 282:7783-7789,
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4. Deshmukh, A.S., J.T. Treebak, Y.C. Long, B. Viollet, J.F.P. Wojtaszewski,
and J.R. Zierath. Role of AMPK subunits in skeletal muscle mTOR signaling.
Mol Endo, 22:1105-1112. 2008.
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5. Chibalin, A.V., Y. Leng, E. Vieira, A. Krook, M. Björnholm, Y.C. Long,
O. Kotova, Z. Zhong, F. Sakane, T. Steiler, C. Nylén, J. Wang, M. Laakso,
M.K. Topham, M. Gilbert, H. Wallberg-Henriksson, and J.R. Zierath. Down-regulation
of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin
resistance. Cell, 132:375-386, 2008.
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6. Bouzakri, K., R. Austin, A. Rune, M.E. Lassman, P.M. Garcia-Roves, J.P.
Berger, A. Krook, A.V. Chibalin, B.B. Zhang, and J.R. Zierath. Malonyl
coenzyme a decarboxylase regulates lipid and glucose metabolism in human
skeletal muscle. Diabetes, 57:1508-1516, 2008.
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7. Cantó C., L.Q. Jiang, A.S. Deshmukh, C. Mataki, A. Coste, M. Lagouge,
J.R. Zierath, and J. Auwerx. Interdependence of AMPK and SIRT1 for metabolic
adaptation to fasting and exercise in skeletal muscle. Cell Metabolism
11:213-219, 2010.
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8. Garcia-Roves P.M., M.E. Osler, M.H. Holmström, J.R. Zierath. Gain-of-function
R225Q mutation in AMP-activated protein kinase gamma 3 subunit increases
mitochondrial biogenesis in glycolytic skeletal muscle. J Biol Chem 283:35724-35734,
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9. Chadt A., K. Leicht, A. Deshmukh, L. Q. Jiang, S. Scherneck, U. Bernhard,
T. Dreja, H. Vogel, K. Schmolz, R. Kluge, J.R. Zierath, C. Hultschig, R.C.
Hoeben, A. Schürmann, H.-G. Joost and H. Al-Hasani. A mutation in Tbc1d1
in the SJL mouse strain confers leanness and protects from high-fat diet
induced obesity. Nature Genetics, 40:1354-1359, 2008.
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10. Barrès, R. M.E. Osler, J. Yan, A. Rune, T. Fritz, K. Caidahl, A. Krook
and J.R. Zierath. Non-CpG methylation of the PGC-1? promoter through DNMT3B
controls mitochondrial density. Cell Metabolism 10:189–198, 2009.