!!Nicholas Turner - Selected Publications
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h-index = 69 : total citations = 18325 (Google Scholar)\\
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RetroBioCat as a Computer-aided Synthesis Planning Tool for Biocatalytic Reactions and Cascades.\\
W. Finnigan, L.J. Hepworth, S.L. Flitsch, S.L. and N.J. Turner, Nature Catal., 2021. https://doi.org/10.1038/s41929-020-00556-z.\\
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Screening and Characterization of a Diverse Panel of Metagenomic Imine Reductases for Biocatalytic Reductive Amination.\\
J.R. Marshall, P. Yao, S.L. Montgomery, J.D. Finnigan, T.W. Thorpe, R.B. Palmer, J. Mangas-Sanchez, R.A.M. Duncan, R.S. Heath, K.M. Graham, D.J. Cook, S.J. Charnock & N.J. Turner, Nature Chem., 2020, DOI: https://doi.org/10.1038/s41557-020-00606-w.\\
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Characterization of Imine Reductases in Reductive Amination for the Exploration of Structure-Activity Relationships.\\
S.L. Montgomery, A. Pushpanath, R.S. Heath, J.R. Marshall, U. Klemstein, J.L. Galman, David Woodlock, S. Bisagni, C.J. Taylor, J. Mangas-Sanchez, J. . Ramsden, Beatriz Dominguez and N.J. Turner, Science Adv., 2020, 6, eaay9320: DOI: 10.1126/sciadv.aay9320.\\
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One-Pot Biocatalytic Cascade Reduction of Cyclic Enimines for the Preparation of Diastereomerically Enriched N-Heterocycles.\\
T.W. Thorpe, S.P. France, S. Hussain, J.R. Marshall, W. Zawodny, J. Mangas-Sanchez, S.L. Montgomery, R.M. Howard, D.S.B. Daniels, R. Kumar, F. Parmeggiani and N.J. Turner, J. Am. Chem. Soc. 2019, 141, 49, 19208–19213.\\
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Biocatalytic N-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades.\\
J.I. Ramsden, R.S. Heath, S.R. Derrington, S.L. Montgomery, J. Mangas-Sanchez, K.R. Mulholland, and NJ. Turner, J. Am. Chem. Soc. 2019, 141, 3, 1201–1206.\\
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Extending the Application of Biocatalysis to Meet the Challenges of Drug Development.\\
P.N. Devine, R.M. Howard, R. Kumar, M.P. Thompson, M.D. Truppo & N.J. Turner, Nature Reviews Chem., 2018, 2, 409–421.\\
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A Reductive Aminase Enzyme from Aspergillus oryzae.\\
G.A. Aleku, S.P. France, J. Mangas-Sanchez, F. Leipold, S. Hussain, S.L. Montgomery, H. Man, G. Grogan and N.J. Turner, Nature Chem., 2017, 9, 961-969.\\
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Structures of Carboxylic Acid Reductase Reveal Domain Dynamics Underlying Catalysis.\\
D. Gahloth, M.S. Dunstan, D. Quaglia, E. Klumbys, M.P. Lockhart-Cairns, A.M. Hill, S.R. Derrington, N. Scrutton, N.J. Turner and D. Leys, Nature Chem. Biol., 2017, 13, 975-981.\\
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One Pot Cascade Synthesis of Mono-and Di-Substituted Piperidines and Pyrrolidines using Carboxylic Acid Reductase (CAR), ω-Transaminase (ω-TA) and Imine Reductase (IRED) Biocatalysts.\\
S.P. France, S. Hussain, A.M. Hill, L.J. Hepworth, R.M. Howard, K.R. Mulholland, S.L. Flitsch and N.J. Turner, ACS Catalysis, 2016, 6, 3753-3759.\\
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Conversion of Alcohols to Enantiopure Amines Through Dual Enzyme Hydrogen-Borrowing Cascades.\\
F.G. Mutti, T. Knaus, N.S. Scrutton, M. Breuer and N.J. Turner, Science, 2015, 349, 1525-1529.