!!Pierre Paoletti - Publications

Total of 55 publications, including 41 as lead author, >7800 citations (Google Scholar)\\
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__Selected publications:__
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* Paoletti P and Ascher P (1994) Mechanosensitivity of NMDA receptors in cultured mouse central neurons. __Neuron__, 13, 645-55.

* Paoletti P, Neyton J and Ascher P (1995) A glycine-independent and subunit-specific potentiation of NMDA responses by extracellular Mg%%sup 2+/%. __Neuron__, 15, 1109-20.

* Paoletti P, Ascher P and Neyton J (1997) High-affinity zinc inhibition of NMDA NR1-NR2A receptors. __Journal of Neuroscience__, 17, 5711-25.

* Paoletti P, Young EC and Siegelbaum SA (1999) C-linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gating. __Journal of General Physiology__, 113, 17-33

* Paoletti P, Perin-Dureau F, Fayyazuddin A, Le Goff A, Callebaut I and Neyton J (2000) Molecular organization of a zinc  binding N-terminal modulatory domain in a NMDA receptor subunit. __Neuron__, 28, 911-25.

* Perin-Dureau F, Rachline J, Neyton J and Paoletti P (2002) Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors. __Journal of Neuroscience__, 22, 5955-65.

* Rachline J, Perin-Dureau F, Le Goff A, Neyton J and Paoletti P (2005) The micromolar zinc-binding domain on the NMDA receptor subunit NR2B. __Journal of Neuroscience__, 25, 308-17.

* Hatton CJ and Paoletti P (2005) Modulation of triheteromeric NMDA receptors by N-terminal domain ligands. __Neuron__, 46, 261-74.

* Neyton J and Paoletti P (2006) Relating NMDA receptor function to receptor subunit composition: limitations of the pharmacological approach. __Journal of Neuroscience__, 26, 1331-33.

* Paoletti P and Neyton J (2007) NMDA receptor subunits: function and pharmacology. __Current Opinion in Pharmacology__, 7, 39-47. (Review)

* Gielen M, Le Goff A, Stroebel D, Johnson JW, Neyton J and Paoletti P (2008) Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition. __Neuron__ 57, 80-93.

* Gielen M, Siegler Rechtless B, Mony L, Johnson JW and Paoletti P (2009) Mechanism of differential control of NMDA receptor activity by NR2 subunits. __Nature__, 459, 703-707.

* Paoletti P, Vergnano A, Barbour B and Casado M (2009) Zinc at glutamatergic synapses.  __Neuroscience__, 158, 126-136. (Review)

* Mony L, Kew JN, Gunthorpe MJ and Paoletti P (2009) Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential. __British Journal of Pharmacolog__y, 157, 1301-1317. (Review)

* Nozaki C, Vergnano A, Filliol D, Ouagazzal A, Le Goff A, Carvalho S, Reiss D, Gaveriaux-Ruff C, Neyton J, Paoletti P# and Kieffer B# (2011) Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit. __Nature Neuroscience__, 14, 1017-1082. #co-senior author

* Mony L, Zhu S, Carvalho S and Paoletti P (2011) Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines. __EMBO Journal__, 30, 3134-3146.

* Paoletti P (2011) Molecular basis of NMDA receptor functional diversity. __European Journal of Neuroscience__, 33(8):1351-65. (Review)

* Zhu S, Stroebel D, Yao CA, Taly A and Paoletti P (2013) Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain. __Nature Structural & Molecular Biology__, 20, 477-485.

* Paoletti P, Bellone C and Zhou Q (2013) NMDA receptor subunit diversity: impact of receptor properties, synaptic plasticity and disease. __Nature Reviews Neuroscience__, 14, 383-400. (Review)

* Zhu S, Riou M, Yao CA, Carvalho S, Rodriguez P, Bensaude O, Paoletti P# and Ye S# (2014) Genetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces. __Proc. Nat. Acad. Sci. (USA)__, 111, 6081-6. #co-senior author 

* Stroebel D, Carvalho S, Grand T, Zhu S and Paoletti P (2014) Controlling NMDA receptor subunit composition using ectopic retention signals. __Journal of Neuroscience__, 34, 16630-6. 

* Vergnano AM, Rebola N, Savtchenko LP, Pinheiro PS, Casado M, Kieffer BL, Rusakov DA, Mulle C and Paoletti P (2014) Zinc dynamics and action at excitatory synapses. __Neuron__, 82(5),1101-14.

* Zhu S and Paoletti P (2015) Allosteric modulators of NMDA receptors: multiple sites and mechanisms. __Current Opinion in Pharmacology__, 20, 14-23. (Review)

* Klippenstein V, Hoppmann C, Ye S, Wang L, Paoletti P (2017) Optocontrol of glutamate receptor gating and permeation by single side-chain photoisomerization. __eLife__, 6, e25808.

* Grand T, Abi Gerges S, David M, Diana MA, Paoletti P (2018) Unmasking GluN1/GluN3A excitatory glycine NMDA receptors. __Nature Communications__, 9(1):4769

* Stroebel D, Casado M, Paoletti P. (2018) Triheteromeric NMDA receptors: from structure to synaptic physiology. __Current Opinion in Physiology__, 2:1-12.

* Esmenjaud JB, Stroebel D, Chan K, Grand T, David M, Wollmuth LP, Taly A, Paoletti P (2019) An inter-dimer allosteric switch controls NMDA receptor activity. __EMBO Journal__, 15;38(2).

* Paoletti P, Ellis-Davies GCR, Mourot A (2019) Optical control of neuronal ion channels and receptors. __Nature Reviews Neuroscience__, Jul 9. doi: 10.1038