!!Jean-Pierre Mothet  - Selected Publications
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Mikou A, Cabayé A, Goupil A, Bertrand H-O, Mothet J-P & Acher FC (2020). Asc-1 transporter (SLC7A10): homology models and molecular dynamics insights into the first steps of the transport mechanism. Scientific Reports 2020 Feb 28;10(1):3731. doi: 10.1038/s41598-020-60617-y\\
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Petrelli F, Dallérac G, Pucci L, Calí C, Zhender T, Sultan S, Lecca S, Chicca A, Ivanov A, Asensio CS, Gundersen V, Toni N, Knott GW, Magara F, Gertsch J, Kirchhoff F, Déglon N, Giros B, Edwards RH, Mothet J-P* & Bezzi P*. (2018). Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments. Molecular Psychiatry doi: 10.1038/s41380-018-0226-y *share seniority, co-corresponding.\\
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Verkhratsky A*, Matteoli M*, Parpura V*, Mothet J-P* & Zorec R* (2016). Astrocytes as secretory cells of the central nervous system: Idiosyncrasies of vesicular secretion. EMBO J 35(3):239-257. *Share seniority, co-corresponding.\\
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Le Bail M, Martineau M, Sacchi S, Yatsenko N, Radzishevsky I, Conrod S, Ait Ouares K, Wolosker H, Pollegioni L, Billard JM & Mothet J-P. (2015). Identity of the NMDA receptor coagonist is synapse specific and developmentally regulated in the hippocampus. Proc Natl Acad Sci USA. 112(2):E204-13. \\
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Martineau M, Shi T, Puyal J, Knolhoff AM, Dulong J, Gasnier B, Klingauf J, Sweedler JV, Jahn R & Mothet J-P. (2013). Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. Journal of Neuroscience 33(8):3413-3423. \\
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Papouin T, Ladépêche L, Ruel J, Sacchi S, Hanini M, Labasque M, Groc L, Pollegioni L, Mothet J-P & Oliet SHR. (2012). Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists. Cell 150(3):630-646. \\
Fossat P, Turpin FR, Dulong J, Sacchi S, Rivet J-M, Pollegioni L, Millan MJ, Oliet SHR & Mothet J-P. (2012). Glial D-serine gates NMDA receptors at excitatory synapses in prefrontal cortex. Cereb Cortex 22(3):595-606. \\
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Martineau M, Baux G & Mothet J-P. (2006). D-Serine signalling in the brain: friend and foe. Trends Neurosci 29(8):481-491.\\
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Mothet J-P, Pollegioni L, Ouanounou G, Martineau M, Fossier P & Baux G. (2005). Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter D-serine. Proc Natl Acad Sci USA 102:5606-5611. \\
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Mothet J-P, Parent AT, Wolosker H, Brady Jr RO, Linden DJ, Ferris CD, Rogawski MA & Snyder SH. (2000). D-Serine is an endogenous ligand for the glycine site of the NMDA receptor. Proc Natl Acad Sci USA 97:4926-4931.