!!Lajos Kemeny - Publications
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__MAJOR DISCOVERIES WITH HIGH IMPACT IN THE FIELD__ \\
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__BASIC RESEARCH. Description toll-like receptors in keratinocytes, their role in skin physiology and pathophysiology__\\
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1. Megyeri K, Orosz L, Bolla S, Erdei L, Razga Z, Seprenyi G, Urban E, Szabo K, Kemeny L: Propionibacterium acnes induces autophagy in keratinocytes: involvement of multiple mechanisms. JOURNAL OF INVESTIGATIVE DERMATOLOGY 138:(4) pp. 750-759. (2018)  Discovery that P. acnes induces autophagy in keratinocytes. Cited by 8.\\
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2. Szabó K , Erdei L , Bolla BS , Tax G , Biró T , Kemeny L: Factors shaping the composition of the cutaneous microbiota. Br J Dermatol 176: 344-351 (2017), A comprehensive review on the effect of microbiome in skin phisiology. Cited by 12.\\
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3.  Nagy I, Pivarcsi A, Kis K, Koreck A, Bodai L, McDowell A, Seltmann H, Patrick S, Zouboulis CC, Kemeny L: Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human sebocytes. MICROBES AND INFECTION 8:(8) pp. 2195-2205. (2006) Discovery that P. acnes modulates the functions of sebocytes. Cited by  231.\\
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4. Nagy I, Pivarcsi A, Koreck A, Széll M, Urbán E, Kemény L: Distinct strains of Propionibacterium acnes induces selective human beta-defensin-2 and interleukin-8 expression in human keratinocytes through Toll-like receptors. JOURNAL OF INVESTIGATIVE DERMATOLOGY 124:(5) pp. 931-938. (2005) Discovery that different P.acnes strains have different effects on immune cells. Cited by 241.\\
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5. Pivarcsi A, Nagy I, Koreck A, Kenderessy-Szabó A, Széll M, Dobozy A, Kemény L: Microbial compounds induce the expression of pro-inflammatory cytokines, chemokines and human beta-defensin-2 in vaginal epithelial cells. MICROBES AND INFECTION 7:(9-10) pp. 1117-1127. (2005) Discovery that microbial compounds affects the immune functions of vaginal epithelial cells. Cited by 110.\\
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6. Pivarcsi A, Bodai L, Rethi B, Kenderessy Szabo A, Koreck A, Szell M, Beer Z, Bata Csorgo Z, Magocsi M, Rajnavolgyi E, Dobozy A, Kemeny L: Expression and function of Toll-like receptors 2 and 4 in human keratinocytes. INTERNATIONAL IMMUNOLOGY 15:(6) pp. 721-730. (2003) Discovery that human epithelial cells have functional toll-like receptors. Cited by 275.\\
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__TRANSLATIONAL RESEARCH.  Identification of new treatment targets and development of new treatments for skin diseases__\\
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7. Manczinger M, Bodnar V, Papp BT, Bolla BS, Szabo K, Balazs B, Csanyi E, Szel E, Eros G, Kemeny L: Drug repurposing by simulating flow through protein-protein interaction networks. CLINICAL PHARMACOLOGY & THERAPEUTICS 103:(3) pp. 511-520. (2018) Development of a new method to find new treatment for skin diseases.  Cited by 2.\\
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8. Koreck AI, Csoma Z, Bodai L, Ignacz F, Kenderessy AS, Kadocsa E, Szabo G, Bor Z, Erdei A, Szony B, Homey B, Dobozy A, Kemeny L: Rhinophototherapy: A new therapeutic tool for the management of allergic rhinitis. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 115:(3) pp. 541-547. (2005) Development of a new, patented device and method for the treatment of allergic rhinitis. Cited by 56.\\
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9.  Baltás E, Csoma Zs, Ignacz F, Dobozy A, Kemény L: Treatment of vitiligo with the 308 nm xenon-chloride excimer laser. ARCHIVES OF  DERMATOLOGY  138 (12)  1619-1921 (2004)  Development of new treatment for vitiligo. Cited by 92.\\
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10. Novák Z, Bónis B, Baltás E, Ocsovszki I, Ignácz F, Dobozy A, Kemény L: Xenon chloride ultraviolet B laser is more effective in treating psoriasis and inducing T cell apoptosis than narrow-band ultraviolet B. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY 67:(1) pp. 32-38. (2002) Development of a new treatment for psoriasis, and explanation for its high efficacy. Cited by 125.