!!Hendrik Coenraad Hemker - Curriculum vitae
Born on July 21, 1934 in Amsterdam, the Netherlands
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__Main present positions__
*Professor and Senior Councillor Cardiovascular Research Institute Maastricht (CARIM)
*General director of “Synapse BV, Research, Development and Consultation in Haemostasis and Thrombosis”, a research company. 
* MD University of Amsterdam 1959
* Ph. D in Biochemistry,  Univ. of Amsterdam 1962 (Prof. Dr. E.C. Slater)
* Head of the research laboratory of the Division of Haemostasis and Thrombosis, Department of Internal Medicine, University of Leyden, 1962-1968.
* Professor of Internal Medicine, for the biochemistry of heart- and vessel diseases, University of Leyden, 1968-1975 continued on a part time basis until 1996.
* Professor of Biochemistry, Chairman of the Department, University of Maastricht 1975-1999.
* Rector Magnificus (~ Vice Chancellor) University of Maastricht 1982-1985.
* Professeur Étranger Université René Descartes (Paris V) Hôpital Necker -Enfants Malades and Université. Pierre et Marie Curie (Paris VI), Hôpital Lariboisière 1984-1987.
* Professeur Étranger Collège de France 1988 
* Affiliate professor of Internal Medicine, Mount Sinai Medical School, New York.1995-2005
__Main Distinctions and Awards:__
*Prix Européen Ganassini (Milano)		1967
*Boerhaave Medal (Leyden)		1974
*Ernst Jung Price (Hamburg)		1985
*Commandeur de l'Ordre des Palmes Académiques (France)	1987
*Member of the Royal Dutch Academy of Arts and Sciences	1987
*Career Award for contributions to Haemostasis and Thrombosis (ISTH)	1987
*Medal of Honor Dutch Federation of Thrombosis Services	1989
*Member of the Academia Europaea		1990
*Chevalier de la Légion d'Honneur (France)	1990
*Honorary member of the Royal Flemisch Academy	1991
*Christiaan Huygens Lecture, Académie des Sciences, Paris	1992
*Dutch Science Foundation, 8 year program grant 	1993
*Honorary Doctorate Xi’An Medical Faculty	1996
*Honorary member of the Dutch Society of Thrombosis and Haemostasis	1997
*Medal of the Medical Faculty Maastricht	1999
*Knight of the order of  "Nederlandse Leeuw" (Royal distinction, The Netherlands)		2000
*Foreign member of the “Académie Nationale de Médecine” (France)	     2001
*Author of over 400 scientific articles and several books.
*Supervisor of over 60 Ph.D. theses.
*Numerous editorial boards; among others1980–2002 Haemostasis (Editor in Chief)
__Main Scientific Achievements before 2000__
*Discovery of uncarboxylated clotting factors (PIVKAs) in vitamin K deficiency (Nature, 1963)
*Discovery of the prothrombin converting enzyme as a complex of factors Xa,Va and phospholipid (Nature 1968)
*Discovery of the role of the antihaemophilic factors A and B as constituents of the factor X activating enzyme complex (Nature 1968)
*With J.Rosing: Discovery of the enzyme mechanistic role of factor Va and phospholipid in prothrombinase (JBC 1980)
*With Chr.Reutelingsberger: Discovery of Annexin V (Vascular AntiCoagulant, Eur J Biochem.1985 )
*With W.Hermens: Development of ellipsometry as a tool in biochemistry of surface-bound reactions.(JBC, 1992-1999)
*With S.Béguin: Clarification of the mode of action of heparins in plasma, rationalisation of heparin determinations, development of standard-independent units for heparin activity. (Thrombosis and Haemostasis, 1987 - ongoing).
*With T.Lindhout and W.Hermens: Thrombin formation at macroscopic surfaces (JBC, 1992-1999)
*With S.Béguin: Discovery and development of the Endogenous Thrombin Potential (ETP) as a universal laboratory probe for hypercoagulability and the effect of anticoagulant drugs (European and USA Patents. Thrombosis and Haemostasis, 1987 - 1993).
*With S.Béguin: Development of methods to determine the Thrombin Generation Curve in defibrinated platelet poor plasma automatically by conversion of special chromogenic substrates. (Thrombosis and Haemostasis1993-1998) 
*With S.Béguin: Discovery that fibrin can activate and provokes procoagulant activity in platelets (Thrombosis and Haemostasis1995-ongoing)
*With S.Béguin: Discovery that von Willebrand factor plays a compulsory role in thrombin generation in platelet rich plasma, together with the receptors GPIIb/IIIa and GPIb (Thrombosis and Haemostasis1997-1999)
*With J.Rosing: Discovery the biological variable in the clotting system that correlates with pill thrombosis (British Journal of Haematology, 1997-ongoing).
*With S.Béguin and P.Giesen: Development of Calibrated Automated Thrombinography (CAT) a method to measure thrombin generation in real time in platelet poor or platelet rich plasma. (Thrombosis and Haemostasis 2000-ongoing) ( patents)