!!John Hardy - Selected Publications
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h-index: 132 \\
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1. Van Broeckhoven C, Haan J, Bakker E, Hardy JA, Van Hul W, Wehnert A, Vegter-Van der Vlis M, Roos RAC. The beta-amyloid precursor protein gene is tightly linked to the locus causing Hereditary Cerebral Hemorrhage with Amyloidosis of Dutch Type. Science 248 (1990) 488-490. \\

2. Goate AM, Chartier-Harlin MC, Mullan MC, Brown J, Crawford F, Fidani L, Giuffra L, Haynes A, Irving N, James L, Mant R, Newton P, Rooke K, Roques P, Talbot C, Pericak-Vance M, Roses A, Williamson R, Rossor MN, Owen M, Hardy J. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer•s disease. Nature 349 (1991) 704-706. \\

3. Chartier-Harlin MC, Crawford F, Houlden H, Warren A, Hughes D, Fidani L, Goate A, Rossor M, Hardy J, Mullan M. Early onset Alzheimer's disease caused by mutations at codon 717 of the b-amyloid precursor protein gene. Nature 353 (1991) 844-846. \\

4. Hardy JA, Higgins GA. Alzheimer's disease: the amyloid cascade hypothesis. Science 286 (1992) 184-185. \\

5. Duff K, Eckman C, Zehr C, Yu X, Prada CM, Pérez-Tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S. Increased amyloid b42(43) in brains of mice expressing mutant presenilin 1. Nature 383 (1996) 710-713. \\

6. Hutton M et al. Coding and splice donor site mutations in tau cause autosomal dominant dementia (FTDP-17). Nature (1998) 393:702-5 \\

7. Lewis J, McGowan E, Rockwood J, Melrose H, Nacharaju P, Van Slegtenhorst M, Gwinn-Hardy K, Murphy MP, Baker M, Yu X, Duff K, Hardy J, Corrall A, Lin WL, Yen SH, Dickson DW, Davies DW, Hutton M. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nature Genet. 25 (2000) 402-405. \\

8. Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, Jones G, Yen SH, Sahara N, Skipper L, Yager D, Eckman C, Hardy J, Hutton M, McGowan E. Enhanced Neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 293 (2001) 1487-1491. \\

9. Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002 Jul 19;297(5580):353-6. \\

10. R. Guerreiro, A. Wojtas, J. Bras, M. Carrasquillo, E. Rogaeva, E. Majounie, C. Cruchaga, C. Sassi, J. S. Kauwe, S. Younkin, L. Hazrati, J. Collinge, J. Pocock, T. Lashley, J. Williams, J. C. Lambert, P. Amouyel, A. Goate, R. Rademakers, K. Morgan, J. Powell, P. St George-Hyslop, A. Singleton, J. Hardy, and Alzheimer Genetic Analysis Group. 2013. Trem2 variants in alzheimer's disease. N Engl J Med 368, no. 2: 117-27. \\
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[Full list of publications|http://www.researcherid.com/rid/C-2451-2009]