!!Manel Esteller - Selected Publications
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Wheeler DA, Takebe N, Hinoue T, Hoadley KA, Cardenas MF, Hamilton AM, Laird PW, Wang L, Johnson A, Dewal N, Miller V, Piñeyro D, Castro de Moura M, Esteller M, Shen H,  [[….]], Conley BA, S. Ivy P, Staudt LM, 2021, 'Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment', Cancer Cell, 39, 1, 38-53.e7.\\
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Mattesen TB, Rasmussen MH, Sandoval J, Ongen H, Árnadóttir SS, Gladov J, Martinez-Cardus A, Castro de Moura M, Madsen AH, Laurberg S, Dermitzakis ET, Esteller M, Andersen CL, Bramsen J, 2020, 'MethCORR Modelling of Methylomes From Formalin-Fixed Paraffin-Embedded Tissue Enables Characterization and Prognostication of Colorectal Cancer', Nat Commun, 11, 1, 2020.\\
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Rosselló-Tortella M, Llinàs-Arias P, Sakaguchi Y, Miyauchi K, Davalos V, Setien F, Calleja-Cervantes ME, Piñeyro D, Martínez-Gómez J, Guil S, Joshi R, Villanueva A, Suzuki T, Esteller M 2020, 'Epigenetic loss of the transfer RNA-modifying enzyme TYW2 induces ribosome frameshifts in colon cancer' Proc Natl Acad Sci USA, 17, 34, 20785-20793. \\
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Ramos-Rodríguez M, Raurell-Vila H, Colli ML, Alvelos MI, Subirana-Granés M, Juan-Mateu J, Norris R, Turatsinze JV, Nakayasu ES, Webb-Robertson BM, Inshaw JRJ, Marchetti P, Piemonti L, Esteller M, Todd JA, Metz TO, Eizirik DL, Pasquali L, 2019. 'The impact of proinflammatory cytokines on the beta-cell regulatory landscape provides insights into the genetics of type 1 diabetes', Nature Genetics, 51, 11, 1588. \\
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Llinàs-Arias P, Rosselló-Tortella M, López-Serra P, Pérez-Salvia M, Setién F, Marin S, Muñoz JP, Junza A, Capellades J, Calleja-Cervantes ME, Ferreira HJ, Castro de Moura M, Srbic M, Martínez-Cardús A, de la Torre C, Villanueva A, Cascante M, Yanes O, Zorzano A, Moutinho C & Esteller M 2019, 'Epigenetic loss of the endoplasmic reticulum-associated degradation inhibitor SVIP induces cancer cell metabolic reprogramming', JCI Insight, 4, 8, e125888.\\
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Berdasco M & Esteller M 2019, 'Clinical Epigenetics: Seizing Opportunities for Translation', Nature Reviews Genetics, 20, 109–127. \\
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Piqué L, Martinez de Paz A, Piñeyro D, Martínez-Cardús A, Castro de Moura M, Llinàs-Arias P, Setien F, Gomez-Miragaya J, Gonzalez-Suarez E, Sigurdsson S, Jonasson JG, Villanueva A, Vidal A, Davalos V & Esteller M 2019, 'Epigenetic Inactivation of the Splicing RNA Binding Protein CELF2 in Human Breast Cancer'. Oncogene, 38, 45, 7106-7112.\\
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Jorge-Torres OC, Szczesna K, Roa L, Casal C, Gonzalez-Somermeyer L, Soler M, Velasco CD, Martínez-San Segundo P, Petazzi P, Sáez MA, Delgado-Morales R, Fourcade S, Pujol A, Huertas D,  Llobet A, Guil S & Esteller M 2018, 'Inhibition of Gsk3b reduces NFk-B signaling and rescues synaptic activity to improve the Rett syndrome phenotype in Mecp2-knockout mice'. Cell Reports, 23, 6, 1665-1677.\\
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Duruisseaux M, Martínez-Cardús A,Calleja-Cervantes ME, Moran S, Castro de Moura M, Davalos V, Piñeyro D, Sanchez-Cespedes M, Girard N, BreveM, Giroux-Leprieur E, Dumenil C, Pradotto M, Bironzo P, Capelleto E, Novello S, Cortot A, Copin MC,..., Moran T, Perez L, Ramos I, Xiao Q, Fernandez AF, Fraga MF, Gut M, Gut I, Teixidó C, Vilariño N, Prat A, Reguart N, Benito A, Garrido P, Barragan I, Emile JF, Rosell R, Brambilla E & Esteller M 2018,  'Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicenter, retrospective analysis', The Lancet Respiratory Medicine, 6, 10, 771-781. \\
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Davalos V, Blanco S & Esteller M 2018, 'SnapShot: Messenger RNA modifications'. Cell, 174 (2):498-498.e1.\\
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Anadón C, Guil S, Simó-Riudalbas L, Moutinho C, Setien F, Martínez-Cardús A, Moran S, Villanueva A, Calaf M, Vidal A, Lazo PA, Zondervan I, Savola S, Kohno T, Yokota J, Ribas de Pouplana L & Esteller M 2016, 'Gene Amplification-Associated Overexpression of the RNA Editing Enzyme ADAR1 Enhances Human Lung Tumorigenesis', Oncogene, 35, 4407-4413. \\
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Moran S, Martínez-Cardús A, Sayols S, Musulén E, Balana C, Estival-Gonzalez A, Moutinho C, Heyn H, Diaz-Lagares A, Castro de Moura M, Stella GM, Comoglio PM, Ruiz-Miró M, Matias-Guiu X, Pazo-Cid R, Antón A, Lopez-Lopez R, Soler G, Longo F, Guerra I, Fernandez S, Assenov Y, Plass C, Morales R, Carles J, Bowtell D, Mileshkin L, Sia D, Tothill R, Tabernero J, Llovet JM & Esteller M 2016, 'Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis', The Lancet Oncology, 17, 1386–1395. \\
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Diaz-Lagares A, Crujeiras AB, Lopez-Serra P, Soler M, Setien F, Goyal A, Sandoval J, Hashimoto Y, Martinez-Cardús A, Gomez A, Heyn H, Moutinho C, Espada J, Vidal A, Paúles M, Galán M, Sala N, Akiyama Y, Martínez-Iniesta M, Farré L, Villanueva A, Gross M, Diederichs S, Guil S & Esteller M 2016, 'Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer', PNAS, 113, 7535-7544.\\
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Ferreira HJ, Heyn H, Vizoso M, Moutinho C, Vidal E, Gomez A, Martinez-Cardus A, Simo-Riudalbas L, Moran S, Jost E & Esteller M 2016, 'DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia', Oncogene, 35, 3079-3082.