!!Marc Delarue - Curriculum Vitae
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__Education__
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*Habilitation in Biological Sciences, University Louis Pasteur in Strasbourg (1993)\\
*Crystallography of Biological Macromolecules (advisor D. Moras), IBMC du CNRS, Univ. L.ouis Pasteur, Strasbourg (1989)\\
*These de 3eme cycle in Molecular Biophysics (advisor Cl. Hélène), University of Paris VI (1984)\\
*Masters in Physics (Maîtrise) and Chemistry (DEA) University of Paris VI (1981 - 1982)\\
*Ecole Normale Supérieure, Physics and Chemistry, Paris (1980-84)
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__Current Position__
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*2012 - now Head of UMR 3528 du CNRS (Institut Pasteur, Paris), DR1 CNRS\\
*2006 - now Head of Unit (PI) "Dynamique Structurale des Macromolecules", Institut Pasteur, Paris
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__Scientific activities__
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*Articles in peer-reviewed international Journals: 120 \\
*Cumulative number of citations > 12000 (Google Scholar)\\
*10 Recommended papers by F1000 in the past 10 years\\
*International Patents: 3\\
*Hirsch h-index: 48 ; i10-index: 94 (Google Scholar)\\
*Book chapters: 4 Articles without reviewing: 2 \\
*Invited Lectures: 45; Published Abstracts from Posters and Talks: 22
*Organization of Meetings or Workshops: 3\\
**France-Stanford Meeting (I.P., Paris, 2010), \\
**Normal Modes for Biological Macromolecules (IP, Paris, 2017)\\
**CECAM Meeting on Normal Modes with Y.H. Sanejouand and K. Hinsen (IHP, Paris, 2018)
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__Teaching activities__
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*Supervision of 7 PhD students, 10 Masters students, 15 post-doctoral fellows\\
*Regular teaching in EMBO workshop courses (Gif/Yvette, then I. Pasteur)\\
*Member of PhD defense committees (10). Tutor of external students (7)
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__Administrative responsibilities and Expertise__
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*Expert for the Marie Curie EC international exchange program (2005-2015), \\
*Expert for the evaluation of ERC Grants (2017-18)\\
*Expert for international grants: Welcome Trust (UK), NWO (NL), FWO (Belgium), AEI (Spain), NSC (Poland), NSF and NIH (USA)\\
*International evaluation of Institutes (Severo Ochoa Excellence Program, Spain)\\
*Reviewer for scientific journals (≈10 per year): Science, PNAS, Nat. Commun., EMBO Rep., eLife, NAR, Proteins, Bioinformatics\\
*Review Editor for Frontiers in Biological Sciences, section Biological Modeling and Simulations
*DB structures: 171 X-ray structures deposited in the PDB (+5 pending)\\
*Reviewer for Beam allocation in LCLS, SLAC, Stanford
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__Fields of Scholarship__
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*Experimental structural biology: crystallography of biological macromolecules; cryo-electron microscopy of large complexes
*Applied structural biology: structure-inspired drug design, homology modeling, prediction of side-chain conformations
*Structural bioinformatics: extracting structural and functional information from sequence databases
*Computational biology: normal mode analysis and exploration of transition paths
*Synthetic biology: incorporation of non-canonical nucleotides in DNA, both in vitro and in vivo
*Systems biology: reverse genetics of modified bases incorporation pathway in some phages
*Statistical physics: application to the study of electrostatic properties of macromolecules
*DNA polymerases: functional studies and engineering for biotechnological applications
*Ligand-gated ion channels: structural basis for gating and allosteric control\\ \\