!!Sylvain Brisse
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__Biography__
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Our research focuses on the microbial population biology and emergence of pathogenic microbial strains, vaccine escape and antimicrobial resistance. We also develop applications in diagnostics and public health, including universal strain subtype genotyping systems and genomic taxonomy systems that facilitate international epidemiological tracking and micro-evolutionary studies. Main studied pathogens are (i) The multidrug resistant pathogen Klebsiella pneumoniae; (ii) Bordetella pertussis, the agent of whooping cough; and (iii) Corynebacterium diphtheriae. Our research combines epidemiological surveillance, experimental microbiology, genomics and bioinformatics approaches.\\
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__Current positions__\\
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Since 2016: Head, Research Unit “Biodiversity and Epidemiology of Bacterial Pathogens”, Institut Pasteur; Director, Natl. Ref. Center for Whooping cough and Other Bordetella infections; Director, Natl. Ref. Center for Corynebacteria of the diphtheriae complex; Coordinator, Pasteur genomic taxonomies of bacterial strains (https://bigsdb.pasteur.fr )\\
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__Education__
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*2005 Accreditation to Supervise Research (‘HDR’), Univ. René Descartes Paris V\\
*1997 PhD in Population Biology and Ecology, Univ. Montpellier II, France\\
*1992 MSc in Cellular and Molecular Biology, Ecole Normale Supérieure ‘rue d’Ulm’
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Example of ongoing research, teaching and surveillance projects - co-PI of the GEnEpi-BioTrain genomic epidemiology capacity building programme (ECDC funded, [https://tinyurl.com/GenEpiBioTrain]);  - co-PI of the KlebNET-Genomic Surveillance Platform project (BMGF funded; [https://klebnet.org]). - Coordinator of curator teams of genomic and multilocus sequence typing databases, [https://www.pasteur.fr/mlst] & [http://bigsdb.pasteur.fr]\\
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__Publications__
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S. Brisse co-authored over 321 peer-reviewed [publications|https://pubmed.ncbi.nlm.nih.gov/?term=brisse+S] (Nov. 2025) \\
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__Teaching – mentoring__
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*PhD and postdocs supervision: >18 since 2008\\
*Thesis defenses committees: >20 since 2005\\
*Teaching and Course organization: Bioinformatics in Clinical Microbiology & antimicrobial resistance (ECDC GenEpi-BioTrain programme; ICARe; SARA project)
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__Other professional activities__
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*Genomic taxonomy of bacterial strains: Coordinator, BIGSdb-Pasteur project ([http://bigsdb.pasteur.fr]); since 2007\\
*Section Head, French Society for Microbiology: Taxonomy, Genomics and Epidemiology, 2005 - present\\
*Executive committee (elected member) of the ESCMID study group on Epidemiological Markers (ESGEM), since 2023\\
*Scientific advisory boards and international conference committees including IP Cambodia, Wellcome Connecting Science Antimicrobial Resistance, IMMEM and KLEBS conferences\\ \\[{ALLOW view All}][{ALLOW edit sbrisse}][{ALLOW upload sbrisse}][{ALLOW comment All}]