Michael Trauner - Publications#


More than 380 Pubmed-listed papers, H-index 60, 10 most important scientific publications:

1. Trauner M, Arrese M, Soroka C, Ananthanarayanan M, Koeppel TA, Schlosser SF, Suchy FJ, Keppler D, Boyer JL. The rat canalicular conjugate export pump (Mrp 2) is down-regulated in intrahepatic and obstructive cholestasis. Gastroenterology 1997; 113: 255-264.

2. Trauner M, Meier PJ, Boyer JL. Molecular pathogenesis of cholestasis. N Engl J Med. 1998 Oct 22;339(17):1217-27. Review

3. Zollner G, Fickert P, Zenz R, Fuchsbichler A, Stumptner C, Kenner L, Ferenci P, Stauber RE, Krejs GJ. Denk H, Zatloukal, Trauner M. Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestasis. Hepatology 2001; 33: 633-646.

4. Wagner M, Fickert P, Zollner G, Fuchsbichler A, Silbert D, Tsybrovskyy O, Zatloukal K, Gonzalez FJ, Marschall HU, Denk H, Trauner M. Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice. Gastroenterology 2003; 125: 825-838.

5. Fickert P, Fuchsbichler A, Wagner M, Zollner G, Kaser A, Tilg H, Krause R, Langner C, Zatloukal K, Marschall HU, Denk H, Trauner M. Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology 2004; 127: 261-274.

6. Fickert P, Wagner M, Marschall HU, Fuchsbichler A, Zollner G, Zatloukal K, Lie J, Waalkes MP, Cover C, Denk H, Hofmann AF, Jaeschke H, Trauner M.. 24-nor-ursodeoxycholic acid as novel therapeutic approach to sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology 2006; 130: 465-481.

7. Baghdasaryan A, Claudel T, Gumhold J, Silbert D, Adorini L, Roda A, VecchiottiS, Gonzalez FJ, Schoonjans K, Strazzabosco M, Fickert P, Trauner M. Dualfarnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/-(Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO₃ output. Hepatology. 2011 Oct;54(4):1303-12.

8. Mueller M, Thorell A, Claudel T, Jha P, Koefeler H, Lackner C, Hoesel B, Fauler G, Stojakovic T, Einarsson C, Marschall HU, Trauner M. Ursodeoxycholic Acid Exerts Farnesoid X Receptor-antagonistic Effects on Bile Acid and Lipid Metabolism in Morbid Obesity. J Hepatol. 2015; 62: 1398-404

9 Baghdasaryan A, Fuchs CD, Österreicher CH, Lemberger UJ, Halilbasic E, Påhlman I, Graffner H, Krones E, Fickert P, Wahlström A, Ståhlman M, Paumgartner G, Marschall HU, Trauner M. Inhibition of Intestinal Bile Acid Absorption Improves Cholestatic Liver and Bile Duct Injury in a Mouse Model of Sclerosing Cholangitis. J Hepatol. 2016; 64: 674-81

10. Fuchs CD, Paumgartner G, Wahlström A, Schwabl P, Reiberger T, Leditznig N, Stojakovic T, Rohr-Udilova N, Chiba P, Marschall HU, Trauner M. Metabolic preconditioning protects BSEP/ABCB11-/- mice against cholestatic liver injury. J Hepatol.2017; 66(1):95-101

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