Michele Vendruscolo#
| Membership Number: | 4511 |
| Membership type: | ORDINARY |
| Section: | BIOCHEMISTRY & MOLECULAR BIOLOGY |
| Elected: | 2017 |
| Main Country of Residence: | UNITED KINGDOM |
| Homepage(s): | http://www-vendruscolo.ch.cam.ac.uk |
Present and Previous Positions
- 2010 - present Professor of Biophysics, University of Cambridge, UK
- 2008 - 2010 Reader in Theoretical Chemical Biology, University of Cambridge, UK
- 2006 - 2008 Lecturer in Theoretical Chemical Biology, University of Cambridge, UK
- 2001 - 2009 Royal Society University Research Fellow, University of Cambridge, UK
- 1999 - 2001 EMBO Long-Term Fellow, University of Oxford, UK
- 1996 - 1998 Sir Charles Clore Postdoctoral Fellow, Weizmann Institute, Israel
- 1993 - 1996 PhD in Condensed Matter Physics, International School for Advanced Studies, Trieste, Italy
- 1992 - 1993 MSc in Condensed Matter Physics, International School for Advanced Studies, Trieste, Italy
- 1992 Laurea (BSc) in Physics, University of Trieste, Italy
Fields of Scholarship
- Mechanisms of protein folding
- Mechanisms of protein misfolding, aggregation and disease
- Development of methods of using molecular dynamics simulations restrained with experimental data for the determination of the structures of non-native states of proteins
- Development of methods for protein structure determination using NMR chemical shifts and residual dipolar couplings
- Development of methods for the rational design of antibodies
- Development of computational and experimental methods to study protein homeostasis
- Elucidation of the molecular origins of Alzheimer's disease and Parkinson's disease
- Discovery of small molecules to prevent or treat Alzheimer's disease and Parkinson's disease
Honours and Awards
- 2016 Founder and Chief Scientific Officer, Wren Therapeutics, Cambridge, Uk
- 2015 Director, Centre for Protein Misfolding Diseases, Cambridge
- 2013 Soft Matter & Biophysical Chemistry Award, Royal Society of Chemistry
- 2013 Fellow of the Royal Society of Chemistry
- 2012 Giorgio Careri Memorial Lecture, Rome (Italy)
- 2011 European Research Council, PE3 Panel Member – Condensed Matter Physics
- 2010 – 2016 Faculty of 1000, Faculty Member, Protein Folding
- 2009 – 2015 European Physical Society, Division of Physics of Life Sciences, Executive Board
- 2007 – 2010 EMBO Young Investigator
- 2007 Jean-Francois Levefre Lecture, Strasbourg (France)
- 2003 – 2006 Research Fellow, Clare Hall, Cambridge
