Janet Thornton - Selected publications#

Macchiarulo, A., Nobeli, I. & Thornton, J.M. (2004) Ligand selectivity and competition between enzymes in silico. Nature Biotechnology. 22, 1039-1045

Porter, C., Bartlett, G. & Thornton, J.M. (2004) The Catalytic Site Atlas (CSA): A Resource of Catalytic Sites and Residues Identified in Enzymes Using Structural Data. Nucleic Acids Research, 32, D129-33

George, R.A., Spriggs, R.G., Bartlett, G.J., Gutteridge, A., MacArthur, M.W., Porter, C.T., Al-Lazikani, B., Thornton, J.M. & Swindells, M.B. (2005) Effective function annotation through residue conservation. PNAS, 102, 12299-12304.

Laskowski, R.A., Watson, J.D. & Thornton, J.M. (2005). ProFunc: a server for predicting protein function from 3D structure. Nucleic Acids Res., 33, W89-W93.

Nobeli, I., Favia, A.D., and Thornton, J.M. (2009). Protein promiscuity and its implications for biotechnology. Nat. Biotechnol. 27, 157-67.

Selman, C., Tullet, J.M., Wieser, D., Irvine, E., Lingard, S.J., Choudhury, A.I., Claret, M., Al-Qassab, H., Carmignac, D., Ramadani, F., Woods, A., Robinson, I.C., Schuster, E., Batterham, R.L., Kozma, S.C., Thomas, G., Carling, D., Okkenhaug, K., Thornton, J.M., Partridge, L., Gems, D., and Withers, D.J. (2009). Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science 326, 140-4.

Oliva, R., Calamita, G., Thornton, J.M., and Pellegrini-Calace, M. (2010). Electrostatics of aquaporin and aquaglyceroporin channels correlates with their transport selectivity. Proc. Natl. Acad. Sci. U. S. A. 107, 4135-40.

Furnham, N., Sillitoe, I., Holliday, G.L., Cuff, A.L., Rahman, S.A., Laskowski, R.A., Orengo, C.A., and Thornton, J.M. (2012). FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies. Nucleic Acids Res. 40, D776-82.

Furnham, Nicholas, Holliday Gemma L., de Beer Tjaart A. P., Jacobsen Julius O. B., Pearson William R., and Thornton Janet M. The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes. Nucleic Acids Res. Volume 42, (2014), p.D485-9 doi: 10.1093/nar/gkt1243

Rahman, Syed A., Cuesta Sergio M., Furnham Nicholas, Holliday Gemma L., and Thornton Janet M.
EC-BLAST: a tool to automatically search and compare enzyme reactions Nature methods. Volume 11, (2014), p.171-4 doi: 10.1038/nmeth.2803