Ingrid Grummt - Selected publications#

• Santoro, R., Li, J., Grummt, I.: The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. In: Nature Genetics 32, 2002. S. 393-396.
• Mayer, C. et al.: mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability. In: Genes Dev. 18, 2004. S. 423-434.
• Mayer, C., Bierhoff, H., Grummt, I.: The nucleolus as a stress sensor: JNK inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis. In: Genes Dev. 19, 2005. S. 933-941.
• Yuan, X. et al.: Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest and p53-mediated apoptosis. In: Mol. Cell 19, 2005. S. 77-89.
• Mayer, C. et al.: Intergenic transcripts regulate the epigenetic state of rRNA genes. In: Mol. Cell 22, 2006. S. 351-361.
• Yuan, X. et al.: Activation of RNA polymerase I transcription by Cockayne Syndrome group B (CSB) protein and histone methyltransferase G9a. In: Mol. Cell 27, 2007. S. 585-595.
• Ye, J. et al.: Nuclear myosin I and polymeric actin act as a molecular motor that drives RNA polymerase I transcription. In: Genes Dev. 22, 2008. S. 322-330.
• Schmitz, K.M. et al.: TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of active genes leading to DNA demethylation. In: Mol. Cell 33, 2009. S. 344-353.
• Zhou, Y. et al.: Acetylation by hMOF regulates NoRC-dependent heterochromatin formation, nucleosome positioning and transcriptional silencing. In: Nature Cell Biol. 11, 2009. S. 1010-1016.
• Feng, W. et al.: The Jumonji-C domain containing histone demethylase PHF8 activates transcription of rRNA genes. In: Nature Struct. Mol. Biol. 17, 2010. S. 445-450.